Zfp609 zinc finger protein 609 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Zfp609provided by RGD
Official Full Name: zinc finger protein 609provided by RGD
Primary source: RGD:1561651
See related: Ensembl:ENSRNOG00000015977 AllianceGenome:RGD:1561651
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Znf609; RGD1561651
Summary: Predicted to enable promoter-specific chromatin binding activity. Predicted to be involved in positive regulation of neuron migration; positive regulation of transcription by RNA polymerase II; and regulation of myoblast proliferation. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Orthologous to human ZNF609 (zinc finger protein 609). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Kidney (RPKM 43.4), Adrenal (RPKM 42.6) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 8q24

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	8	NC_086026.1 (75109676..75243045, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	8	NC_051343.1 (66214553..66349319, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	8	NC_005107.4 (71230830..71337746, complement)

Chromosome 8 - NC_086026.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Circular RNA-ZNF609 regulates corneal neovascularization by acting as a sponge of miR-184.
Title: Circular RNA-ZNF609 regulates corneal neovascularization by acting as a sponge of miR-184.
cZNF609 acted as an endogenous miR-615 sponge to sequester and inhibit miR-615 activity, which led to increased METRN.
Title: Circular RNA-ZNF609 regulates retinal neurodegeneration by acting as miR-615 sponge.

Submit: New GeneRIF Correction

General gene information

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Markers

RH127706 (e-PCR)
- UniSTS:211016

AI045538 (e-PCR)
- UniSTS:248400

D8Rat62 (e-PCR)
- UniSTS:119127

D8Rat93 (e-PCR)
- UniSTS:119140

RH133973 (e-PCR)
- UniSTS:217255

40.MHAa92d4.seq (e-PCR)
- UniSTS:124352

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables promoter-specific chromatin binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in positive regulation of neuron migration	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of transcription by RNA polymerase II	ISO Inferred from Sequence Orthology more info
involved_in regulation of myoblast proliferation	ISO Inferred from Sequence Orthology more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of transcription by RNA polymerase II	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: zinc finger protein 609

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001173371.1 → NP_001166842.1 zinc finger protein 609

See identical proteins and their annotated locations for NP_001166842.1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000008

UniProtKB/TrEMBL

D4ACN4

Related

ENSRNOP00000021554.5, ENSRNOT00000021554.7

Conserved Domains (2) summary

PTZ00449
Location:1007 → 1226

PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional

COG5189
Location:412 → 533

SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086026.1 Reference GRCr8

Range

75109676..75243045 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039081824.2 → XP_038937752.1 zinc finger protein 609 isoform X1

UniProtKB/TrEMBL

D4ACN4

Conserved Domains (2) summary

PTZ00449
Location:1007 → 1226

PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional

COG5189
Location:412 → 533

SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
XM_063265861.1 → XP_063121931.1 zinc finger protein 609 isoform X2

UniProtKB/TrEMBL

A6J5G3
XM_063265862.1 → XP_063121932.1 zinc finger protein 609 isoform X3