U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from MedGen

    • Showing Current items.

    AOPEP aminopeptidase O (putative) [ Homo sapiens (human) ]

    Gene ID: 84909, updated on 5-Mar-2024

    Summary

    Official Symbol
    AOPEPprovided by HGNC
    Official Full Name
    aminopeptidase O (putative)provided by HGNC
    Primary source
    HGNC:HGNC:1361
    See related
    Ensembl:ENSG00000148120 MIM:619600; AllianceGenome:HGNC:1361
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    APO; AP-O; DYT31; ONPEP; C90RF3; C9orf3
    Summary
    This gene encodes a member of the M1 zinc aminopeptidase family. The encoded protein is a zinc-dependent metallopeptidase that catalyzes the removal of an amino acid from the amino terminus of a protein or peptide. This protein may play a role in the generation of angiotensin IV. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010]
    Expression
    Ubiquitous expression in skin (RPKM 4.6), endometrium (RPKM 4.2) and 24 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See AOPEP in Genome Data Viewer
    Location:
    9q22.32
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (94726699..95150224)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (106896013..107317676)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (97488981..97849441)

    Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene NANOG hESC enhancer GRCh37_chr9:97370327-97370828 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:97372257-97372756 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20057 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28632 Neighboring gene Sharpr-MPRA regulatory region 4124 Neighboring gene uncharacterized LOC124902219 Neighboring gene fructose-bisphosphatase 1 Neighboring gene uncharacterized LOC107987101 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr9:97482699-97483898 Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:97488708-97489250 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:97506143-97506644 Neighboring gene uncharacterized LOC124902220 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28635 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr9:97587461-97588134 Neighboring gene microRNA 2278 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28636 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_110389 Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:97634019-97634518 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_110405 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_110431 Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:97678815-97679315 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:97680413-97680914 Neighboring gene uncharacterized LOC101928119 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:97689588-97690377 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:97690378-97691166 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:97691883-97692383 Neighboring gene ReSE screen-validated silencer GRCh37_chr9:97712716-97712894 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20058 Neighboring gene Sharpr-MPRA regulatory region 10357 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:97741836-97742834 Neighboring gene Sharpr-MPRA regulatory region 2222 Neighboring gene Sharpr-MPRA regulatory region 14176 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20061 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20060 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20059 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr9:97780096-97781295 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr9:97785561-97786760 Neighboring gene ReSE screen-validated silencer GRCh37_chr9:97791169-97791319 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:97794537-97795036 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:97807172-97807937 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20062 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:97825060-97825769 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:97852235-97852984 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:97853735-97854484 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:97852985-97853734 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:97863941-97864440 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:97865305-97865951 Neighboring gene uncharacterized LOC107987102 Neighboring gene microRNA 6081 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20063 Neighboring gene Sharpr-MPRA regulatory region 10736 Neighboring gene Sharpr-MPRA regulatory region 8238 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:97894463-97894965 Neighboring gene microRNA 3074 Neighboring gene microRNA 24-1 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:97900452-97901082 Neighboring gene microRNA 27b Neighboring gene microRNA 23b Neighboring gene ribosomal protein S26 pseudogene 37 Neighboring gene FA complementation group C Neighboring gene RNA, 5S ribosomal pseudogene 288 Neighboring gene small nucleolar RNA U13 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_110513 Neighboring gene Sharpr-MPRA regulatory region 1665 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_110548 Neighboring gene Sharpr-MPRA regulatory region 1693 Neighboring gene ATM interactor pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    Associated conditions

    Description Tests
    Dystonia 31
    MedGen: C5562001 OMIM: 619565 GeneReviews: Not available
    not available

    EBI GWAS Catalog

    Description
    Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome.
    EBI GWAS Catalog
    Genome-wide association study to identify single nucleotide polymorphisms (SNPs) associated with the development of erectile dysfunction in African-American men after radiotherapy for prostate cancer.
    EBI GWAS Catalog
    Meta-analysis identifies six new susceptibility loci for atrial fibrillation.
    EBI GWAS Catalog
    Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
    EBI GWAS Catalog

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ14675, FLJ40923, FLJ55832

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables metalloaminopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleolus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_027833.2 RefSeqGene

      Range
      5002..365462
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001193329.3NP_001180258.1  aminopeptidase O isoform 1

      See identical proteins and their annotated locations for NP_001180258.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1).
      Source sequence(s)
      AL157936, AL353768, AL354893
      Consensus CDS
      CCDS55328.1
      UniProtKB/Swiss-Prot
      Q5T9B1, Q5T9B3, Q5T9B4, Q8N6M6, Q8WUL6, Q96M23, Q96SS1
      Related
      ENSP00000364464.2, ENST00000375315.8
      Conserved Domains (2) summary
      pfam09127
      Location:721818
      Leuk-A4-hydro_C; Leukotriene A4 hydrolase, C-terminal
      cl14813
      Location:244652
      GluZincin; Gluzincin Peptidase family (thermolysin-like proteinases, TLPs) which includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins)
    2. NM_001193331.3NP_001180260.1  aminopeptidase O isoform 4

      See identical proteins and their annotated locations for NP_001180260.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) lacks multiple 3' exons, but has an alternate 3' exon, as compared to variant 1. The resulting isoform (4) is much shorter and has a different C-terminus, as compared to isoform 1.
      Source sequence(s)
      AK057450, AK098242, AL353768, BX099259, DA521148
      Consensus CDS
      CCDS55327.1
      UniProtKB/Swiss-Prot
      Q8N6M6
      Related
      ENSP00000277198.2, ENST00000277198.6
      Conserved Domains (1) summary
      cl14813
      Location:244509
      GluZincin; Gluzincin Peptidase family (thermolysin-like proteinases, TLPs) which includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins)
    3. NM_001386061.1NP_001372990.1  aminopeptidase O isoform 5

      Status: REVIEWED

      Source sequence(s)
      AL157936, AL353768, AL354893
      Conserved Domains (2) summary
      pfam09127
      Location:291341
      Leuk-A4-hydro_C; Leukotriene A4 hydrolase, C-terminal
      cl14813
      Location:141222
      GluZincin; Gluzincin Peptidase family (thermolysin-like proteinases, TLPs) which includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins)
    4. NM_001386062.2NP_001372991.1  aminopeptidase O isoform 6

      Status: REVIEWED

      Source sequence(s)
      AL157936, AL353768, AL354893
      Conserved Domains (2) summary
      pfam09127
      Location:614711
      Leuk-A4-hydro_C; Leukotriene A4 hydrolase, C-terminal
      cl14813
      Location:317545
      GluZincin; Gluzincin Peptidase family (thermolysin-like proteinases, TLPs) which includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins)
    5. NM_001386063.2NP_001372992.1  aminopeptidase O isoform 7

      Status: REVIEWED

      Source sequence(s)
      AL157936, AL353768, AL354893
      Conserved Domains (2) summary
      pfam09127
      Location:675772
      Leuk-A4-hydro_C; Leukotriene A4 hydrolase, C-terminal
      cl14813
      Location:244652
      GluZincin; Gluzincin Peptidase family (thermolysin-like proteinases, TLPs) which includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins)
    6. NM_001386066.1NP_001372995.1  aminopeptidase O isoform 3

      Status: REVIEWED

      Source sequence(s)
      AL157936, AL353768, AL354893
      Conserved Domains (2) summary
      pfam09127
      Location:721771
      Leuk-A4-hydro_C; Leukotriene A4 hydrolase, C-terminal
      cl14813
      Location:244652
      GluZincin; Gluzincin Peptidase family (thermolysin-like proteinases, TLPs) which includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins)
    7. NM_001386067.1NP_001372996.1  aminopeptidase O isoform 8

      Status: REVIEWED

      Source sequence(s)
      AL157936, AL353768, AL354893
      Conserved Domains (2) summary
      pfam09127
      Location:547597
      Leuk-A4-hydro_C; Leukotriene A4 hydrolase, C-terminal
      cl14813
      Location:244453
      GluZincin; Gluzincin Peptidase family (thermolysin-like proteinases, TLPs) which includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins)
    8. NM_001386068.1NP_001372997.1  aminopeptidase O isoform 3

      Status: REVIEWED

      Source sequence(s)
      AL157936, AL353768, AL354893
      Conserved Domains (2) summary
      pfam09127
      Location:721771
      Leuk-A4-hydro_C; Leukotriene A4 hydrolase, C-terminal
      cl14813
      Location:244652
      GluZincin; Gluzincin Peptidase family (thermolysin-like proteinases, TLPs) which includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins)
    9. NM_001386069.1NP_001372998.1  aminopeptidase O isoform 9

      Status: REVIEWED

      Source sequence(s)
      AL157936, AL353768, AL354893
      Conserved Domains (2) summary
      pfam09127
      Location:622672
      Leuk-A4-hydro_C; Leukotriene A4 hydrolase, C-terminal
      cl14813
      Location:244553
      GluZincin; Gluzincin Peptidase family (thermolysin-like proteinases, TLPs) which includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins)
    10. NM_001386070.1NP_001372999.1  aminopeptidase O isoform 10

      Status: REVIEWED

      Source sequence(s)
      AL157936, AL353768, AL354893
      Conserved Domains (2) summary
      pfam09127
      Location:706732
      Leuk-A4-hydro_C; Leukotriene A4 hydrolase, C-terminal
      cl14813
      Location:244652
      GluZincin; Gluzincin Peptidase family (thermolysin-like proteinases, TLPs) which includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins)
    11. NM_001386071.1NP_001373000.1  aminopeptidase O isoform 4

      Status: REVIEWED

      Source sequence(s)
      AL157936, AL353768
      Consensus CDS
      CCDS55327.1
      Conserved Domains (1) summary
      cl14813
      Location:244509
      GluZincin; Gluzincin Peptidase family (thermolysin-like proteinases, TLPs) which includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins)
    12. NM_001386072.1NP_001373001.1  aminopeptidase O isoform 11

      Status: REVIEWED

      Source sequence(s)
      AL157936, AL353768
      Conserved Domains (1) summary
      cl14813
      Location:244509
      GluZincin; Gluzincin Peptidase family (thermolysin-like proteinases, TLPs) which includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins)
    13. NM_001386073.1NP_001373002.1  aminopeptidase O isoform 12

      Status: REVIEWED

      Source sequence(s)
      AL157936, AL353768
      Conserved Domains (1) summary
      cl14813
      Location:2219
      GluZincin; Gluzincin Peptidase family (thermolysin-like proteinases, TLPs) which includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins)
    14. NM_001386074.1NP_001373003.1  aminopeptidase O isoform 13

      Status: REVIEWED

      Source sequence(s)
      AL157936, AL353768, AL354893
      Conserved Domains (2) summary
      pfam09127
      Location:721771
      Leuk-A4-hydro_C; Leukotriene A4 hydrolase, C-terminal
      cl14813
      Location:244652
      GluZincin; Gluzincin Peptidase family (thermolysin-like proteinases, TLPs) which includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins)
    15. NM_001386075.1NP_001373004.1  aminopeptidase O isoform 1

      Status: REVIEWED

      Source sequence(s)
      AL157936, AL353768, AL354893
      Consensus CDS
      CCDS55328.1
      UniProtKB/Swiss-Prot
      Q5T9B1, Q5T9B3, Q5T9B4, Q8N6M6, Q8WUL6, Q96M23, Q96SS1
      Conserved Domains (2) summary
      pfam09127
      Location:721818
      Leuk-A4-hydro_C; Leukotriene A4 hydrolase, C-terminal
      cl14813
      Location:244652
      GluZincin; Gluzincin Peptidase family (thermolysin-like proteinases, TLPs) which includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins)
    16. NM_001386076.1NP_001373005.1  aminopeptidase O isoform 14

      Status: REVIEWED

      Source sequence(s)
      AL157936, AL353768
      Conserved Domains (1) summary
      cl14813
      Location:244652
      GluZincin; Gluzincin Peptidase family (thermolysin-like proteinases, TLPs) which includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins)
    17. NM_032823.6NP_116212.3  aminopeptidase O isoform 2

      See identical proteins and their annotated locations for NP_116212.3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) lacks two consecutive in-frame exons in the CDS, as compared to variant 1. The resulting isoform (2) is shorter than isoform 1.
      Source sequence(s)
      AI982632, AL354893, BC029616, DA521148
      Consensus CDS
      CCDS6713.1
      UniProtKB/Swiss-Prot
      Q8N6M6
      Related
      ENSP00000297979.5, ENST00000297979.9
      Conserved Domains (2) summary
      pfam09127
      Location:617718
      Leuk-A4-hydro_C; Leukotriene A4 hydrolase, C-terminal
      cl14813
      Location:186533
      GluZincin; Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins)

    RNA

    1. NR_169862.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AL157936, AL353768, AL354893
    2. NR_169863.2 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AL157936, AL353768, AL354893
    3. NR_169864.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AL157936, AL353768, AL354893
    4. NR_169865.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AL157936, AL353768, AL354893
    5. NR_169866.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AL157936, AL353768, AL354893
    6. NR_169867.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AL353768, AL354893

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

      Range
      94726699..95150224
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011519121.4XP_011517423.1  aminopeptidase O isoform X2

      Conserved Domains (2) summary
      cd09595
      Location:186632
      M1; Peptidase M1 family contains aminopeptidase N and leukotriene A4 hydrolase
      pfam09127
      Location:716781
      Leuk-A4-hydro_C; Leukotriene A4 hydrolase, C-terminal
    2. XM_047423984.1XP_047279940.1  aminopeptidase O isoform X5

    3. XM_017015234.3XP_016870723.1  aminopeptidase O isoform X12

      Conserved Domains (2) summary
      pfam09127
      Location:419474
      Leuk-A4-hydro_C; Leukotriene A4 hydrolase, C-terminal
      cl14813
      Location:27335
      GluZincin; Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins)
    4. XM_017015236.3XP_016870725.1  aminopeptidase O isoform X15

    5. XM_047423978.1XP_047279934.1  aminopeptidase O isoform X1

      UniProtKB/Swiss-Prot
      Q5T9B1, Q5T9B3, Q5T9B4, Q8N6M6, Q8WUL6, Q96M23, Q96SS1
    6. XM_017015231.3XP_016870720.1  aminopeptidase O isoform X6

      UniProtKB/Swiss-Prot
      Q8N6M6
      Conserved Domains (2) summary
      pfam09127
      Location:617718
      Leuk-A4-hydro_C; Leukotriene A4 hydrolase, C-terminal
      cl14813
      Location:186533
      GluZincin; Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins)
    7. XM_047423987.1XP_047279943.1  aminopeptidase O isoform X13

    8. XM_017015237.3XP_016870726.1  aminopeptidase O isoform X17

    9. XM_047423983.1XP_047279939.1  aminopeptidase O isoform X4

    10. XM_047423981.1XP_047279937.1  aminopeptidase O isoform X4

    11. XM_047423980.1XP_047279936.1  aminopeptidase O isoform X4

    12. XM_017015232.3XP_016870721.1  aminopeptidase O isoform X8

    13. XM_047423985.1XP_047279941.1  aminopeptidase O isoform X11

    14. XM_047423988.1XP_047279944.1  aminopeptidase O isoform X18

    15. XM_047423982.1XP_047279938.1  aminopeptidase O isoform X4

    16. XM_011519123.4XP_011517425.1  aminopeptidase O isoform X9

      Conserved Domains (1) summary
      cd09595
      Location:186632
      M1; Peptidase M1 family contains aminopeptidase N and leukotriene A4 hydrolase
    17. XM_011519122.4XP_011517424.1  aminopeptidase O isoform X7

      Conserved Domains (1) summary
      cd09595
      Location:186632
      M1; Peptidase M1 family contains aminopeptidase N and leukotriene A4 hydrolase
    18. XM_011519127.3XP_011517429.1  aminopeptidase O isoform X10

      Conserved Domains (1) summary
      cd09595
      Location:186625
      M1; Peptidase M1 family contains aminopeptidase N and leukotriene A4 hydrolase
    19. XM_011519130.3XP_011517432.1  aminopeptidase O isoform X14

      Conserved Domains (1) summary
      cl14813
      Location:186456
      GluZincin; Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins)
    20. XM_011519134.4XP_011517436.1  aminopeptidase O isoform X16

      Conserved Domains (1) summary
      cl14813
      Location:186455
      GluZincin; Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins)
    21. XM_047423979.1XP_047279935.1  aminopeptidase O isoform X3

    22. XM_047423986.1XP_047279942.1  aminopeptidase O isoform X12

    23. XM_011519132.2XP_011517434.1  aminopeptidase O isoform X19

      Conserved Domains (2) summary
      pfam09127
      Location:336391
      Leuk-A4-hydro_C; Leukotriene A4 hydrolase, C-terminal
      cl14813
      Location:1252
      GluZincin; Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins)

    RNA

    1. XR_929854.3 RNA Sequence

    2. XR_929853.3 RNA Sequence

    3. XR_007061364.1 RNA Sequence

    4. XR_007061363.1 RNA Sequence

    5. XR_929855.3 RNA Sequence

    6. XR_929857.3 RNA Sequence

    7. XR_007061365.1 RNA Sequence

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060933.1 Alternate T2T-CHM13v2.0

      Range
      106896013..107317676
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054364031.1XP_054220006.1  aminopeptidase O isoform X2

    2. XM_054364037.1XP_054220012.1  aminopeptidase O isoform X5

    3. XM_054364044.1XP_054220019.1  aminopeptidase O isoform X12

    4. XM_054364048.1XP_054220023.1  aminopeptidase O isoform X15

    5. XM_054364030.1XP_054220005.1  aminopeptidase O isoform X1

      UniProtKB/Swiss-Prot
      Q5T9B1, Q5T9B3, Q5T9B4, Q8N6M6, Q8WUL6, Q96M23, Q96SS1
    6. XM_054364038.1XP_054220013.1  aminopeptidase O isoform X6

    7. XM_054364046.1XP_054220021.1  aminopeptidase O isoform X13

    8. XM_054364050.1XP_054220025.1  aminopeptidase O isoform X17

    9. XM_054364036.1XP_054220011.1  aminopeptidase O isoform X4

    10. XM_054364034.1XP_054220009.1  aminopeptidase O isoform X4

    11. XM_054364033.1XP_054220008.1  aminopeptidase O isoform X4

    12. XM_054364040.1XP_054220015.1  aminopeptidase O isoform X8

    13. XM_054364043.1XP_054220018.1  aminopeptidase O isoform X11

    14. XM_054364051.1XP_054220026.1  aminopeptidase O isoform X18

    15. XM_054364035.1XP_054220010.1  aminopeptidase O isoform X4

    16. XM_054364041.1XP_054220016.1  aminopeptidase O isoform X9

    17. XM_054364039.1XP_054220014.1  aminopeptidase O isoform X7

    18. XM_054364042.1XP_054220017.1  aminopeptidase O isoform X10

    19. XM_054364047.1XP_054220022.1  aminopeptidase O isoform X14

    20. XM_054364049.1XP_054220024.1  aminopeptidase O isoform X16

    21. XM_054364032.1XP_054220007.1  aminopeptidase O isoform X3

    22. XM_054364045.1XP_054220020.1  aminopeptidase O isoform X12

    RNA

    1. XR_008488088.1 RNA Sequence

    2. XR_008488087.1 RNA Sequence

    3. XR_008488091.1 RNA Sequence

    4. XR_008488090.1 RNA Sequence

    5. XR_008488089.1 RNA Sequence

    6. XR_008488092.1 RNA Sequence

    7. XR_008488093.1 RNA Sequence

    8. XR_008488094.1 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001193330.1: Suppressed sequence

      Description
      NM_001193330.1: This RefSeq was temporarily suppressed because currently there is not sufficient data to support this transcript.