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    Cxcl15 chemokine (C-X-C motif) ligand 15 [ Mus musculus (house mouse) ]

    Gene ID: 20309, updated on 31-Oct-2021

    Summary

    Official Symbol
    Cxcl15provided by MGI
    Official Full Name
    chemokine (C-X-C motif) ligand 15provided by MGI
    Primary source
    MGI:MGI:1339941
    See related
    Ensembl:ENSMUSG00000029375
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Il8; weche; Scyb15; lungkine
    Expression
    Restricted expression toward lung adult (RPKM 125.0) See more
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    Genomic context

    See Cxcl15 in Genome Data Viewer
    Location:
    5 E1; 5 44.78 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (90942393..90950926)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (90794534..90803067)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (91223560..91232093)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene platelet factor 4 Neighboring gene chemokine (C-X-C motif) ligand 3 Neighboring gene chemokine (C-X-C motif) ligand 1 Neighboring gene chemokine (C-X-C motif) ligand 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables CXCR chemokine receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables chemokine activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables chemokine activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables cytokine activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in antimicrobial humoral immune response mediated by antimicrobial peptide IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in cellular response to lipopolysaccharide IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in chemokine-mediated signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within chemotaxis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in defense response IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within hemopoiesis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in inflammatory response IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within inflammatory response IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in neutrophil chemotaxis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within neutrophil chemotaxis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    C-X-C motif chemokine 15
    Names
    interleukin 8
    small inducible cytokine subfamily B, member 15
    small-inducible cytokine B15

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011339.2NP_035469.1  C-X-C motif chemokine 15 precursor

      See identical proteins and their annotated locations for NP_035469.1

      Status: VALIDATED

      Source sequence(s)
      AK142955
      Consensus CDS
      CCDS19418.1
      UniProtKB/Swiss-Prot
      Q9WVL7
      Related
      ENSMUSP00000031322.7, ENSMUST00000031322.7
      Conserved Domains (1) summary
      cd00273
      Location:2790
      Chemokine_CXC; Chemokine_CXC: 1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; many members ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      90942393..90950926
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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