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    CG1677 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31662, updated on 10-May-2024

    Summary

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    Official Symbol
    CG1677provided by FlyBase
    Primary source
    FLYBASE:FBgn0029941
    Locus tag
    Dmel_CG1677
    See related
    AllianceGenome:FB:FBgn0029941
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG1677
    Summary
    Predicted to enable mRNA cap binding complex binding activity and protein-macromolecule adaptor activity. Predicted to be involved in RNA destabilization. Part of catalytic step 2 spliceosome and precatalytic spliceosome. Is expressed in embryonic brain; embryonic/larval midgut; larval ventral nerve cord; organism; and spermatozoon. Orthologous to human ZC3H18 (zinc finger CCCH-type containing 18). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG1677 in Genome Data Viewer
    Location:
    7A8-7B2; 1-20 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (7281089..7405797, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (7175122..7299830, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR32730 Neighboring gene long non-coding RNA:CR44357 Neighboring gene Chronophage Neighboring gene uncharacterized protein Neighboring gene unc-119 Neighboring gene uncharacterized protein Neighboring gene brinker Neighboring gene Autophagy-related 5 Neighboring gene uncharacterized protein Neighboring gene Acyl-CoA synthetase family member 3 Neighboring gene Downstream of kinase Neighboring gene uncharacterized protein Neighboring gene sarcoplasmic calcium-binding protein Neighboring gene uncharacterized protein Neighboring gene Chemosensory protein A 7a Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Fine-mapping and selective sweep analysis of QTL for cold tolerance in Drosophila melanogaster. Wilches R, et al. G3 (Bethesda), 2014 Jun 26. PMID 24970882, Free PMC Article
    2. Evidence of gene conversion associated with a selective sweep in Drosophila melanogaster. Glinka S, et al. Mol Biol Evol, 2006 Oct. PMID 16868022
    3. The genetic basis and adult reproductive consequences of developmental thermal plasticity. Rodrigues LR, et al. J Anim Ecol, 2022 Jun. PMID 35060127, Free PMC Article
    4. The BET protein FSH functionally interacts with ASH1 to orchestrate global gene activity in Drosophila. Kockmann T, et al. Genome Biol, 2013 Feb 25. PMID 23442797, Free PMC Article
    5. Expression profiling of glial genes during Drosophila embryogenesis. Altenhein B, et al. Dev Biol, 2006 Aug 15. PMID 16762338

    See all (47) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables mRNA cap binding complex binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-macromolecule adaptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA destabilization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in mRNA splicing, via spliceosome IC
    Inferred by Curator
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of catalytic step 2 spliceosome HDA PubMed 
    part_of precatalytic spliceosome HDA PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG1677-PA
    CG1677-PB
    CG1677-PC
    CG1677-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      7281089..7405797 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_167124.3 → NP_727178.1  uncharacterized protein Dmel_CG1677, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_727178.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E5N2, Q9W3R9
      Conserved Domains (1) summary
      smart00356
      Location:419 → 440
      ZnF_C3H1; zinc finger

    2. NM_132159.3 → NP_572387.1  uncharacterized protein Dmel_CG1677, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572387.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E5N2, Q9W3R9
      Related
      FBpp0088653
      Conserved Domains (1) summary
      smart00356
      Location:419 → 440
      ZnF_C3H1; zinc finger

    3. NM_001298048.1 → NP_001284977.1  uncharacterized protein Dmel_CG1677, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284977.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E5N2, X2JE07
      Conserved Domains (1) summary
      smart00356
      Location:419 → 440
      ZnF_C3H1; zinc finger

    4. NM_001298047.1 → NP_001284976.1  uncharacterized protein Dmel_CG1677, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284976.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E5N2, Q9W3R9
      Conserved Domains (1) summary
      smart00356
      Location:419 → 440
      ZnF_C3H1; zinc finger
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MYV4 Q8MYV4
    Q9W3R9 Q9W3R9
    X2JE07 X2JE07

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