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    Syde1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans) [ Mus musculus (house mouse) ]

    Gene ID: 71709, updated on 16-Oct-2021

    Summary

    Official Symbol
    Syde1provided by MGI
    Official Full Name
    synapse defective 1, Rho GTPase, homolog 1 (C. elegans)provided by MGI
    Primary source
    MGI:MGI:1918959
    See related
    Ensembl:ENSMUSG00000032714
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mSYD1A; BB043000; 1200008N06Rik
    Expression
    Broad expression in lung adult (RPKM 28.5), adrenal adult (RPKM 26.5) and 24 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Syde1 in Genome Data Viewer
    Location:
    10; 10 C1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (78420336..78427798, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (78584502..78591964, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (78047248..78054709, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene vomeronasal 2, receptor, pseudogene 92 Neighboring gene ilvB (bacterial acetolactate synthase)-like Neighboring gene predicted gene, 30346 Neighboring gene olfactory receptor 1357

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GTPase activator activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables GTPase activator activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    enables GTPase regulator activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein-containing complex binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cerebellar mossy fiber IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in synaptic membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    rho GTPase-activating protein SYDE1
    Names
    protein syd-1 homolog 1
    synapse defective protein 1 homolog 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027875.1NP_082151.1  rho GTPase-activating protein SYDE1

      See identical proteins and their annotated locations for NP_082151.1

      Status: VALIDATED

      Source sequence(s)
      AC153887
      Consensus CDS
      CCDS48613.1
      UniProtKB/TrEMBL
      G3X960
      Related
      ENSMUSP00000043085.7, ENSMUST00000040580.7
      Conserved Domains (2) summary
      pfam16885
      Location:73250
      CAC1F_C; Voltage-gated calcium channel subunit alpha, C-term
      cl02570
      Location:396601
      RhoGAP; RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      78420336..78427798 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006514148.1XP_006514211.1  rho GTPase-activating protein SYDE1 isoform X1

      Conserved Domains (2) summary
      PHA03247
      Location:57263
      PHA03247; large tegument protein UL36; Provisional
      cl02570
      Location:396529
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

    RNA

    1. XR_001779604.2 RNA Sequence

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