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    Sec61a1 Sec61 alpha 1 subunit (S. cerevisiae) [ Mus musculus (house mouse) ]

    Gene ID: 53421, updated on 16-Oct-2021

    Summary

    Official Symbol
    Sec61a1provided by MGI
    Official Full Name
    Sec61 alpha 1 subunit (S. cerevisiae)provided by MGI
    Primary source
    MGI:MGI:1858417
    See related
    Ensembl:ENSMUSG00000030082
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Sec61a; AA408394; AA410007
    Expression
    Ubiquitous expression in ovary adult (RPKM 174.0), large intestine adult (RPKM 157.8) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Sec61a1 in Genome Data Viewer
    Location:
    6; 6 D1
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (88480589..88495782, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (88503607..88518800, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (88453601..88468794, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene eukaryotic elongation factor, selenocysteine-tRNA-specific Neighboring gene predicted gene, 44264 Neighboring gene RuvB-like protein 1 Neighboring gene predicted gene, 46965 Neighboring gene kelch repeat and BTB (POZ) domain containing 12 Neighboring gene predicted gene, 26588 Neighboring gene monoglyceride lipase

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables calcium channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables ribosome binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables ribosome binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables ribosome binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables signal sequence binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables transmembrane transporter activity EXP
    Inferred from Experiment
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of Sec61 translocon complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in phagocytic vesicle membrane TAS
    Traceable Author Statement
    more info
     
    located_in rough endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    protein transport protein Sec61 subunit alpha isoform 1
    Names
    SEC61, alpha subunit
    protein transport protein Sec61 subunit alpha
    sec61 alpha-1
    transport protein sec61 alpha subunit

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_016906.4NP_058602.1  protein transport protein Sec61 subunit alpha isoform 1

      See identical proteins and their annotated locations for NP_058602.1

      Status: PROVISIONAL

      Source sequence(s)
      AC154038
      Consensus CDS
      CCDS39553.1
      UniProtKB/Swiss-Prot
      P61620
      Related
      ENSMUSP00000032168.6, ENSMUST00000032168.7
      Conserved Domains (1) summary
      PTZ00219
      Location:1471
      PTZ00219; Sec61 alpha subunit; Provisional

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      88480589..88495782 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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