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    Extl3 exostosin-like glycosyltransferase 3 [ Mus musculus (house mouse) ]

    Gene ID: 54616, updated on 16-Aug-2021

    Summary

    Official Symbol
    Extl3provided by MGI
    Official Full Name
    exostosin-like glycosyltransferase 3provided by MGI
    Primary source
    MGI:MGI:1860765
    See related
    Ensembl:ENSMUSG00000021978
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ext1l; AU040105; mKIAA0519; 2900009G18Rik
    Expression
    Ubiquitous expression in subcutaneous fat pad adult (RPKM 31.2), mammary gland adult (RPKM 19.2) and 27 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Extl3 in Genome Data Viewer
    Location:
    14; 14 D1
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (65289508..65387349, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (65052059..65149899, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (65670896..65716943, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene homeobox containing 1 Neighboring gene high mobility group nucleosomal binding domain 2, pseudogene Neighboring gene integrator complex subunit 9 Neighboring gene predicted gene, 52118 Neighboring gene predicted gene, 52119 Neighboring gene predicted gene, 30008 Neighboring gene predicted gene, 41177 Neighboring gene frizzled class receptor 3 Neighboring gene predicted gene 9086

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (2)  1 citation
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • KIAA0519

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables glycosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables glycosyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in heparan sulfate proteoglycan biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of cell growth ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    exostosin-like 3
    Names
    exostoses (multiple)-like 3
    exostoses-like 3
    exostosin
    glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase
    multiple exostosis-like protein 3
    NP_001347314.1
    NP_061258.2
    XP_006519347.1
    XP_006519349.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001360385.1NP_001347314.1  exostosin-like 3

      Status: VALIDATED

      Source sequence(s)
      AC155172, BC065073, CJ129577, CO044892
      Consensus CDS
      CCDS27211.1
      Conserved Domains (3) summary
      pfam03016
      Location:190500
      Exostosin; Exostosin family
      pfam07926
      Location:76150
      TPR_MLP1_2; TPR/MLP1/MLP2-like protein
      pfam09258
      Location:663900
      Glyco_transf_64; Glycosyl transferase family 64 domain
    2. NM_018788.3NP_061258.2  exostosin-like 3

      See identical proteins and their annotated locations for NP_061258.2

      Status: VALIDATED

      Source sequence(s)
      AC155172, BC065073, CJ129577, CO044892
      Consensus CDS
      CCDS27211.1
      UniProtKB/TrEMBL
      Q6P1H4
      Related
      ENSMUSP00000022550.8, ENSMUST00000022550.8
      Conserved Domains (3) summary
      pfam03016
      Location:190500
      Exostosin; Exostosin family
      pfam07926
      Location:76150
      TPR_MLP1_2; TPR/MLP1/MLP2-like protein
      pfam09258
      Location:663900
      Glyco_transf_64; Glycosyl transferase family 64 domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      65289508..65387349 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006519284.3XP_006519347.1  exostosin-like 3 isoform X1

      See identical proteins and their annotated locations for XP_006519347.1

      UniProtKB/TrEMBL
      Q6P1H4
      Conserved Domains (3) summary
      pfam03016
      Location:190500
      Exostosin; Exostosin family
      pfam07926
      Location:76150
      TPR_MLP1_2; TPR/MLP1/MLP2-like protein
      pfam09258
      Location:663900
      Glyco_transf_64; Glycosyl transferase family 64 domain
    2. XM_006519286.4XP_006519349.1  exostosin-like 3 isoform X1

      See identical proteins and their annotated locations for XP_006519349.1

      UniProtKB/TrEMBL
      Q6P1H4
      Conserved Domains (3) summary
      pfam03016
      Location:190500
      Exostosin; Exostosin family
      pfam07926
      Location:76150
      TPR_MLP1_2; TPR/MLP1/MLP2-like protein
      pfam09258
      Location:663900
      Glyco_transf_64; Glycosyl transferase family 64 domain
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