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    MYH11 myosin heavy chain 11 [ Bos taurus (cattle) ]

    Gene ID: 530050, updated on 5-Mar-2024

    Summary

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    Official Symbol
    MYH11provided by VGNC
    Official Full Name
    myosin heavy chain 11provided by VGNC
    Primary source
    VGNC:VGNC:31795
    See related
    Ensembl:ENSBTAG00000015988
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 25
    Exon count:
    43
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 25 NC_037352.1 (14124960..14252429, complement)

    Chromosome 25 - NC_037352.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112444307 Neighboring gene meiosis regulator and mRNA stability factor 1 Neighboring gene microRNA mir-484 Neighboring gene nudE neurodevelopment protein 1 Neighboring gene centrosomal protein 20 Neighboring gene rho-related GTP-binding protein RhoA-B-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037352.1 Chromosome 25 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sinusoidal length oscillation- and receptor-mediated mRNA expression of myosin isoforms and alpha-SM actin in airway smooth muscle. Wahl M, et al. Am J Physiol Cell Physiol, 2004 Dec. PMID 15317664
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC137876

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cytoskeletal motor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of myosin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    myosin-11
    Names
    myosin heavy chain SMA
    myosin, heavy chain 11, smooth muscle

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001102127.1 → NP_001095597.1  myosin-11

      See identical proteins and their annotated locations for NP_001095597.1

      Status: PROVISIONAL

      Source sequence(s)
      BC148029
      UniProtKB/TrEMBL
      A6QLN6, F1MYM9
      Related
      ENSBTAP00000066629.1, ENSBTAT00000081607.2
      Conserved Domains (10) summary
      cl14654
      Location:1020 → 1292
      V_Alix_like; Protein-interacting V-domain of mammalian Alix and related domains
      cd14921
      Location:99 → 771
      MYSc_Myh11; class II myosin heavy chain 11, motor domain
      pfam00063
      Location:87 → 771
      Myosin_head; Myosin head (motor domain)
      pfam01576
      Location:848 → 1928
      Myosin_tail_1; Myosin tail
      pfam02736
      Location:34 → 71
      Myosin_N; Myosin N-terminal SH3-like domain
      pfam08286
      Location:1525 → 1580
      Spc24; Spc24 subunit of Ndc80
      pfam16046
      Location:990 → 1082
      FAM76; FAM76 protein
      cd16269
      Location:1896 → 1907
      GBP_C; coiled coil [structural motif]
      cl20817
      Location:1831 → 1925
      GBP_C; Guanylate-binding protein, C-terminal domain
      cl24005
      Location:1779 → 1867
      DUF2570; Protein of unknown function (DUF2570)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037352.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      14124960..14252429 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024984962.2 → XP_024840730.1  myosin-11 isoform X1

      UniProtKB/TrEMBL
      F1MYM9
      Related
      ENSBTAP00000059861.2, ENSBTAT00000067717.2
      Conserved Domains (3) summary
      cd01377
      Location:99 → 778
      MYSc_class_II; class II myosins, motor domain
      pfam01576
      Location:855 → 1935
      Myosin_tail_1; Myosin tail
      pfam02736
      Location:33 → 71
      Myosin_N; Myosin N-terminal SH3-like domain

    2. XM_024984963.2 → XP_024840731.1  myosin-11 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1MG42
      Related
      ENSBTAP00000073213.2, ENSBTAT00000086021.2
      Conserved Domains (3) summary
      cd01377
      Location:99 → 778
      MYSc_class_II; class II myosins, motor domain
      pfam01576
      Location:855 → 1935
      Myosin_tail_1; Myosin tail
      pfam02736
      Location:33 → 71
      Myosin_N; Myosin N-terminal SH3-like domain
    Nucleotide Protein Strain
    Heading Accession and Version

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