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    TOMM7 translocase of outer mitochondrial membrane 7 [ Homo sapiens (human) ]

    Gene ID: 54543, updated on 7-Aug-2021

    Summary

    Official Symbol
    TOMM7provided by HGNC
    Official Full Name
    translocase of outer mitochondrial membrane 7provided by HGNC
    Primary source
    HGNC:HGNC:21648
    See related
    Ensembl:ENSG00000196683 MIM:607980
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    TOM7
    Summary
    This gene encodes a subunit of the translocase of the outer mitochondrial membrane. The encoded protein regulates the assembly and stability of the translocase complex. [provided by RefSeq, Oct 2012]
    Expression
    Ubiquitous expression in ovary (RPKM 141.3), fat (RPKM 120.2) and 25 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See TOMM7 in Genome Data Viewer
    Location:
    7p15.3
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    109.20210514 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (22812974..22822849, complement)
    105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (22852593..22862468, complement)

    Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene MT-CYB pseudogene 42 Neighboring gene ribosomal protein S26 pseudogene 32 Neighboring gene uncharacterized LOC112267993 Neighboring gene small nucleolar RNA host gene 26 Neighboring gene small nucleolar RNA, C/D box 93

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    Associated conditions

    Description Tests
    Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.
    GeneReviews: Not available

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    General protein information

    Preferred Names
    mitochondrial import receptor subunit TOM7 homolog
    Names
    translocase of outer membrane 7 kDa subunit homolog
    translocase of outer mitochondrial membrane 7 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019059.5NP_061932.1  mitochondrial import receptor subunit TOM7 homolog

      See identical proteins and their annotated locations for NP_061932.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and is the protein-coding variant.
      Source sequence(s)
      AC005682
      Consensus CDS
      CCDS5376.1
      UniProtKB/Swiss-Prot
      Q9P0U1
      UniProtKB/TrEMBL
      Q75MR5
      Related
      ENSP00000351214.4, ENST00000358435.9
      Conserved Domains (1) summary
      pfam08038
      Location:953
      Tom7; TOM7 family

    RNA

    1. NR_168014.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC005682
    2. NR_168015.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC005682

    RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

      Range
      22812974..22822849 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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