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    Pyroxd1 pyridine nucleotide-disulphide oxidoreductase domain 1 [ Mus musculus (house mouse) ]

    Gene ID: 232491, updated on 23-Jun-2021

    Summary

    Official Symbol
    Pyroxd1provided by MGI
    Official Full Name
    pyridine nucleotide-disulphide oxidoreductase domain 1provided by MGI
    Primary source
    MGI:MGI:2676395
    See related
    Ensembl:ENSMUSG00000041671
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 5.3), CNS E14 (RPKM 4.4) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Pyroxd1 in Genome Data Viewer
    Location:
    6; 6 G2
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (142291353..142311527)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (142345627..142362729)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (142294217..142311144)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene solute carrier organic anion transporter family, member 1a5 Neighboring gene islet amyloid polypeptide Neighboring gene 60S ribosomal protein L18 pseudogene Neighboring gene RecQ protein-like Neighboring gene golgi transport 1B Neighboring gene spexin hormone

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (3) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cellular response to oxidative stress ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in sarcomere ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1
    NP_898988.2
    XP_006507017.1
    XP_017177048.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_183165.3NP_898988.2  pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1

      See identical proteins and their annotated locations for NP_898988.2

      Status: PROVISIONAL

      Source sequence(s)
      AK165677
      Consensus CDS
      CCDS20681.1
      UniProtKB/Swiss-Prot
      Q3TMV7
      Related
      ENSMUSP00000036394.8, ENSMUST00000041852.8
      Conserved Domains (1) summary
      pfam07992
      Location:76381
      Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      142291353..142311527
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017321559.3XP_017177048.1  pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 isoform X2

      Conserved Domains (2) summary
      COG1251
      Location:104298
      NirB; NAD(P)H-nitrite reductase, large subunit [Energy production and conversion]
      cl39093
      Location:91187
      Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase
    2. XM_006506954.5XP_006507017.1  pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006507017.1

      Conserved Domains (2) summary
      COG1251
      Location:230424
      NirB; NAD(P)H-nitrite reductase, large subunit [Energy production and conversion]
      cl39093
      Location:28313
      Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase

    RNA

    1. XR_003956192.2 RNA Sequence

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