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    RUFY3 RUN and FYVE domain containing 3 [ Canis lupus familiaris (dog) ]

    Gene ID: 475168, updated on 5-Mar-2024

    Summary

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    Official Symbol
    RUFY3provided by VGNC
    Official Full Name
    RUN and FYVE domain containing 3provided by VGNC
    Primary source
    VGNC:VGNC:45805
    See related
    Ensembl:ENSCAFG00845010948
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 13
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 13 NC_051817.1 (60813185..60885065)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 13 NC_006595.4 (59741413..59813528)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 13 NC_049234.1 (61067046..61138949)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 13 NC_049273.1 (60427868..60499800)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 13 NC_049754.1 (59919548..59991670)

    Chromosome 13 - NC_051817.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119874469 Neighboring gene UTP3 small subunit processome component Neighboring gene uncharacterized LOC106559653 Neighboring gene G-rich RNA sequence binding factor 1 Neighboring gene small nucleolar RNA SNORA62/SNORA6 family

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of axonogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein RUFY3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051817.1 Reference ROS_Cfam_1.0

      Range
      60813185..60885065
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038685848.1 → XP_038541776.1  protein RUFY3 isoform X7

      UniProtKB/TrEMBL
      A0A8C0NQ18
      Conserved Domains (2) summary
      TIGR02168
      Location:302 → 503
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam02759
      Location:162 → 283
      RUN; RUN domain

    2. XM_038685849.1 → XP_038541777.1  protein RUFY3 isoform X8

      UniProtKB/TrEMBL
      A0A8C0QCG3, A0A8I3RYG5
      Related
      ENSCAFP00845015562.1, ENSCAFT00845019869.1
      Conserved Domains (2) summary
      COG1196
      Location:276 → 482
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam02759
      Location:121 → 242
      RUN; RUN domain

    3. XM_038685843.1 → XP_038541771.1  protein RUFY3 isoform X2

      UniProtKB/TrEMBL
      A0A8C0RYB9
      Conserved Domains (3) summary
      COG1196
      Location:297 → 514
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd15744
      Location:568 → 615
      FYVE_RUFY3; FYVE-related domain found in RUN and FYVE domain-containing protein 3 (RUFY3) and similar proteins
      pfam02759
      Location:121 → 242
      RUN; RUN domain

    4. XM_038685845.1 → XP_038541773.1  protein RUFY3 isoform X4

      UniProtKB/TrEMBL
      A0A8P0T5E7
      Conserved Domains (2) summary
      TIGR02168
      Location:261 → 523
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam02759
      Location:121 → 242
      RUN; RUN domain

    5. XM_038685847.1 → XP_038541775.1  protein RUFY3 isoform X6

      UniProtKB/TrEMBL
      A0A8P0T5E7
      Conserved Domains (2) summary
      COG1196
      Location:271 → 570
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam02759
      Location:121 → 242
      RUN; RUN domain

    6. XM_038685842.1 → XP_038541770.1  protein RUFY3 isoform X1

      UniProtKB/TrEMBL
      A0A8C0RYB9, A0A8P0PAR5
      Conserved Domains (3) summary
      TIGR02168
      Location:261 → 523
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd15744
      Location:579 → 626
      FYVE_RUFY3; FYVE-related domain found in RUN and FYVE domain-containing protein 3 (RUFY3) and similar proteins
      pfam02759
      Location:121 → 242
      RUN; RUN domain

    7. XM_038685850.1 → XP_038541778.1  protein RUFY3 isoform X9

      UniProtKB/TrEMBL
      A0A8C0LP27, A0A8C0QCG3, A0A8C0RMF9, A0A8P0T293
      Related
      ENSCAFP00845015529.1, ENSCAFT00845019835.1
      Conserved Domains (2) summary
      COG1196
      Location:258 → 464
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam02759
      Location:103 → 224
      RUN; RUN domain

    8. XM_038685844.1 → XP_038541772.1  protein RUFY3 isoform X3

      UniProtKB/TrEMBL
      A0A8C0LNC3, A0A8C0NS86, A0A8I3NHR9, A0A8P0P4G3
      Related
      ENSCAFP00845015459.1, ENSCAFT00845019754.1
      Conserved Domains (3) summary
      TIGR02168
      Location:243 → 505
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd15744
      Location:561 → 608
      FYVE_RUFY3; FYVE-related domain found in RUN and FYVE domain-containing protein 3 (RUFY3) and similar proteins
      pfam02759
      Location:103 → 224
      RUN; RUN domain

    9. XM_038685846.1 → XP_038541774.1  protein RUFY3 isoform X5

      UniProtKB/TrEMBL
      A0A8C0QL97, A0A8I3NTY5
      Related
      ENSCAFP00845015608.1, ENSCAFT00845019925.1
      Conserved Domains (3) summary
      TIGR02168
      Location:213 → 475
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd15744
      Location:531 → 578
      FYVE_RUFY3; FYVE-related domain found in RUN and FYVE domain-containing protein 3 (RUFY3) and similar proteins
      pfam02759
      Location:73 → 194
      RUN; RUN domain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049273.1 Alternate UMICH_Zoey_3.1

      Range
      60427868..60499800
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038493989.1 → XP_038349917.1  protein RUFY3 isoform X7

    2. XM_038493988.1 → XP_038349916.1  protein RUFY3 isoform X15

    3. XM_038493982.1 → XP_038349910.1  protein RUFY3 isoform X11

    4. XM_038493981.1 → XP_038349909.1  protein RUFY3 isoform X10

    5. XM_038493990.1 → XP_038349918.1  protein RUFY3 isoform X8

    6. XM_038493983.1 → XP_038349911.1  protein RUFY3 isoform X12

    7. XM_038493984.1 → XP_038349912.1  protein RUFY3 isoform X13

    8. XM_038493985.1 → XP_038349913.1  protein RUFY3 isoform X1

    9. XM_038493991.1 → XP_038349919.1  protein RUFY3 isoform X9

    10. XM_038493986.1 → XP_038349914.1  protein RUFY3 isoform X3

    11. XM_038493987.1 → XP_038349915.1  protein RUFY3 isoform X14

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049754.1 Alternate UNSW_CanFamBas_1.0

      Range
      59919548..59991670
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038620217.1 → XP_038476145.1  protein RUFY3 isoform X7

    2. XM_038620216.1 → XP_038476144.1  protein RUFY3 isoform X21

    3. XM_038620211.1 → XP_038476139.1  protein RUFY3 isoform X17

    4. XM_038620215.1 → XP_038476143.1  protein RUFY3 isoform X20

    5. XM_038620218.1 → XP_038476146.1  protein RUFY3 isoform X8

      Conserved Domains (2) summary
      COG1196
      Location:276 → 482
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam02759
      Location:121 → 242
      RUN; RUN domain

    6. XM_038620209.1 → XP_038476137.1  protein RUFY3 isoform X16

    7. XM_038620210.1 → XP_038476138.1  protein RUFY3 isoform X1

    8. XM_038620212.1 → XP_038476140.1  protein RUFY3 isoform X18

    9. XM_038620219.1 → XP_038476147.1  protein RUFY3 isoform X9

      Conserved Domains (2) summary
      COG1196
      Location:258 → 464
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam02759
      Location:103 → 224
      RUN; RUN domain

    10. XM_038620213.1 → XP_038476141.1  protein RUFY3 isoform X3

    11. XM_038620214.1 → XP_038476142.1  protein RUFY3 isoform X19

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049234.1 Alternate UU_Cfam_GSD_1.0

      Range
      61067046..61138949
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038556280.1 → XP_038412208.1  protein RUFY3 isoform X7

      UniProtKB/TrEMBL
      A0A8C0NQ18
      Conserved Domains (2) summary
      TIGR02168
      Location:299 → 500
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam02759
      Location:159 → 280
      RUN; RUN domain

    2. XM_038556279.1 → XP_038412207.1  protein RUFY3 isoform X27

      UniProtKB/TrEMBL
      A0A8C0NPZ6
      Conserved Domains (3) summary
      TIGR02168
      Location:179 → 441
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd15744
      Location:502 → 549
      FYVE_RUFY3; FYVE-related domain found in RUN and FYVE domain-containing protein 3 (RUFY3) and similar proteins
      pfam02759
      Location:39 → 160
      RUN; RUN domain

    3. XM_038556274.1 → XP_038412202.1  protein RUFY3 isoform X23

      UniProtKB/TrEMBL
      A0A8C0RYB9
      Conserved Domains (3) summary
      COG1196
      Location:297 → 514
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd15744
      Location:573 → 620
      FYVE_RUFY3; FYVE-related domain found in RUN and FYVE domain-containing protein 3 (RUFY3) and similar proteins
      pfam02759
      Location:121 → 242
      RUN; RUN domain

    4. XM_038556278.1 → XP_038412206.1  protein RUFY3 isoform X26

      UniProtKB/TrEMBL
      A0A8P0T5E7

    5. XM_038556281.1 → XP_038412209.1  protein RUFY3 isoform X8

      UniProtKB/TrEMBL
      A0A8C0QCG3, A0A8I3RYG5
      Conserved Domains (2) summary
      COG1196
      Location:276 → 482
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam02759
      Location:121 → 242
      RUN; RUN domain

    6. XM_038556272.1 → XP_038412200.1  protein RUFY3 isoform X22

      UniProtKB/TrEMBL
      A0A8C0RYB9

    7. XM_038556273.1 → XP_038412201.1  protein RUFY3 isoform X1

      UniProtKB/TrEMBL
      A0A8C0RYB9, A0A8P0PAR5
      Conserved Domains (3) summary
      TIGR02168
      Location:261 → 523
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd15744
      Location:579 → 626
      FYVE_RUFY3; FYVE-related domain found in RUN and FYVE domain-containing protein 3 (RUFY3) and similar proteins
      pfam02759
      Location:121 → 242
      RUN; RUN domain

    8. XM_038556275.1 → XP_038412203.1  protein RUFY3 isoform X24

      UniProtKB/TrEMBL
      A0A8C0NS86

    9. XM_038556282.1 → XP_038412210.1  protein RUFY3 isoform X9

      UniProtKB/TrEMBL
      A0A8C0LP27, A0A8C0QCG3, A0A8C0RMF9, A0A8P0T293
      Conserved Domains (2) summary
      COG1196
      Location:258 → 464
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam02759
      Location:103 → 224
      RUN; RUN domain

    10. XM_038556276.1 → XP_038412204.1  protein RUFY3 isoform X3

      UniProtKB/TrEMBL
      A0A8C0LNC3, A0A8C0NS86, A0A8I3NHR9, A0A8P0P4G3
      Conserved Domains (3) summary
      TIGR02168
      Location:243 → 505
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd15744
      Location:561 → 608
      FYVE_RUFY3; FYVE-related domain found in RUN and FYVE domain-containing protein 3 (RUFY3) and similar proteins
      pfam02759
      Location:103 → 224
      RUN; RUN domain

    11. XM_038556277.1 → XP_038412205.1  protein RUFY3 isoform X25

      UniProtKB/TrEMBL
      A0A8C0QL97

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006595.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      59741413..59813528
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003431831.5 → XP_003431879.3  protein RUFY3 isoform X7

      UniProtKB/TrEMBL
      A0A8C0NQ18
      Conserved Domains (2) summary
      TIGR02168
      Location:301 → 502
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam02759
      Location:161 → 282
      RUN; RUN domain

    2. XM_022427080.2 → XP_022282788.2  protein RUFY3 isoform X28

      UniProtKB/TrEMBL
      A0A8C0NPZ6
      Conserved Domains (3) summary
      TIGR02168
      Location:179 → 441
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd15744
      Location:497 → 544
      FYVE_RUFY3; FYVE-related domain found in RUN and FYVE domain-containing protein 3 (RUFY3) and similar proteins
      pfam02759
      Location:39 → 160
      RUN; RUN domain

    3. XM_038430801.1 → XP_038286729.1  protein RUFY3 isoform X2

      UniProtKB/TrEMBL
      A0A8C0RYB9
      Conserved Domains (3) summary
      COG1196
      Location:297 → 514
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd15744
      Location:568 → 615
      FYVE_RUFY3; FYVE-related domain found in RUN and FYVE domain-containing protein 3 (RUFY3) and similar proteins
      pfam02759
      Location:121 → 242
      RUN; RUN domain

    4. XM_014118842.3 → XP_013974317.1  protein RUFY3 isoform X8

      UniProtKB/TrEMBL
      A0A8C0QCG3, A0A8I3RYG5
      Conserved Domains (2) summary
      COG1196
      Location:276 → 482
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam02759
      Location:121 → 242
      RUN; RUN domain

    5. XM_038430802.1 → XP_038286730.1  protein RUFY3 isoform X4

      UniProtKB/TrEMBL
      A0A8P0T5E7
      Conserved Domains (2) summary
      TIGR02168
      Location:261 → 523
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam02759
      Location:121 → 242
      RUN; RUN domain

    6. XM_038430804.1 → XP_038286732.1  protein RUFY3 isoform X6

      UniProtKB/TrEMBL
      A0A8P0T5E7
      Conserved Domains (2) summary
      COG1196
      Location:271 → 570
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam02759
      Location:121 → 242
      RUN; RUN domain

    7. XM_005628273.4 → XP_005628330.1  protein RUFY3 isoform X1

      UniProtKB/TrEMBL
      A0A8C0RYB9, A0A8P0PAR5
      Conserved Domains (3) summary
      TIGR02168
      Location:261 → 523
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd15744
      Location:579 → 626
      FYVE_RUFY3; FYVE-related domain found in RUN and FYVE domain-containing protein 3 (RUFY3) and similar proteins
      pfam02759
      Location:121 → 242
      RUN; RUN domain

    8. XM_532400.7 → XP_532400.3  protein RUFY3 isoform X9

      See identical proteins and their annotated locations for XP_532400.3

      UniProtKB/TrEMBL
      A0A8C0LP27, A0A8C0QCG3, A0A8C0RMF9, A0A8P0T293
      Conserved Domains (2) summary
      COG1196
      Location:258 → 464
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam02759
      Location:103 → 224
      RUN; RUN domain

    9. XM_857342.6 → XP_862435.1  protein RUFY3 isoform X3

      UniProtKB/TrEMBL
      A0A8C0LNC3, A0A8C0NS86, A0A8I3NHR9, A0A8P0P4G3
      Conserved Domains (3) summary
      TIGR02168
      Location:243 → 505
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd15744
      Location:561 → 608
      FYVE_RUFY3; FYVE-related domain found in RUN and FYVE domain-containing protein 3 (RUFY3) and similar proteins
      pfam02759
      Location:103 → 224
      RUN; RUN domain

    10. XM_022427084.1 → XP_022282792.1  protein RUFY3 isoform X5

      UniProtKB/TrEMBL
      A0A8C0QL97, A0A8P0T020
      Conserved Domains (3) summary
      cd15744
      Location:531 → 578
      FYVE_RUFY3; FYVE-related domain found in RUN and FYVE domain-containing protein 3 (RUFY3) and similar proteins
      pfam02759
      Location:73 → 194
      RUN; RUN domain
      cl25732
      Location:213 → 470
      SMC_N; RecF/RecN/SMC N terminal domain
    Nucleotide Protein
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