Format

Send to:

Choose Destination

Links from Nucleotide

    • Showing Current items.

    Rpia ribose 5-phosphate isomerase A [ Mus musculus (house mouse) ]

    Gene ID: 19895, updated on 23-Jun-2021

    Summary

    Official Symbol
    Rpiaprovided by MGI
    Official Full Name
    ribose 5-phosphate isomerase Aprovided by MGI
    Primary source
    MGI:MGI:103254
    See related
    Ensembl:ENSMUSG00000053604
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    RPI
    Expression
    Ubiquitous expression in liver E14 (RPKM 26.2), liver E14.5 (RPKM 22.8) and 27 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Rpia in Genome Data Viewer
    Location:
    6 C1; 6 32.06 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (70742704..70769159, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (70765720..70792175, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (70715714..70742169, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene immunoglobulin kappa chain complex Neighboring gene predicted gene, 30211 Neighboring gene predicted gene, 30331 Neighboring gene eukaryotic translation initiation factor 2 alpha kinase 3 Neighboring gene predicted gene, 23346 Neighboring gene immunoglobulin kappa constant

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables carbohydrate binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables monosaccharide binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables ribose-5-phosphate isomerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables ribose-5-phosphate isomerase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables ribose-5-phosphate isomerase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in D-ribose metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in pentose-phosphate shunt ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in pentose-phosphate shunt, non-oxidative branch IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in pentose-phosphate shunt, non-oxidative branch ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in ribose phosphate metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ribose-5-phosphate isomerase
    Names
    phosphoriboisomerase
    NP_033101.2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009075.2NP_033101.2  ribose-5-phosphate isomerase

      See identical proteins and their annotated locations for NP_033101.2

      Status: VALIDATED

      Source sequence(s)
      AC156398, AK137235, CO043650
      Consensus CDS
      CCDS39504.1
      UniProtKB/Swiss-Prot
      P47968
      Related
      ENSMUSP00000064158.6, ENSMUST00000066134.6
      Conserved Domains (1) summary
      cd01398
      Location:74291
      RPI_A; RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      70742704..70769159 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center