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    mt:CoI mitochondrial Cytochrome c oxidase subunit I [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 19893533, updated on 26-Apr-2024

    Summary

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    Official Symbol
    mt:CoIprovided by FlyBase
    Official Full Name
    mitochondrial Cytochrome c oxidase subunit Iprovided by FlyBase
    Primary source
    FLYBASE:FBgn0013674
    Locus tag
    Dmel_CG34067
    See related
    AllianceGenome:FB:FBgn0013674
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    mt:CoI; COX1
    Summary
    Enables cytochrome-c oxidase activity. Involved in mitochondrial electron transport, cytochrome c to oxygen. Part of respiratory chain complex IV. Is expressed in adult head. Orthologous to human MT-CO1 (mitochondrially encoded cytochrome c oxidase I). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See mt:CoI in Genome Data Viewer
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) MT (non-nuclear) NC_024511.2 (1474..3009)

    Chromosome MT - NC_024511.2Genomic Context describing neighboring genes Neighboring gene mitochondrial transfer RNA:Tryptophan-TCA Neighboring gene mitochondrial transfer RNA:Cysteine-GCA Neighboring gene mitochondrial transfer RNA:Tyrosine-GTA Neighboring gene mitochondrial transfer RNA:Leucine-TAA Neighboring gene mitochondrial Cytochrome c oxidase subunit II

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_024511.2 Chromosome MT Reference Release 6 plus ISO1 MT non-nuclear

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The gender-specific impact of starvation on mitotypes diversity in adults of Drosophila melanogaster. Wang T, et al. Open Biol, 2022 Sep. PMID 36167086, Free PMC Article
    2. Drosophila melanogaster microbiome is shaped by strict filtering and neutrality along a latitudinal cline. Henry LP, et al. Mol Ecol, 2022 Nov. PMID 36094780, Free PMC Article
    3. Development of a PCR-RFLP assay to identify Drosophila melanogaster among field-collected larvae. Raquin V, et al. Ecol Evol, 2018 Oct. PMID 30397448, Free PMC Article
    4. MITOCHONDRIAL DNA PHYLOGENIES FOR THE DROSOPHILA OBSCURA GROUP. Gleason JM, et al. Evolution, 1997 Apr. PMID 28565356
    5. The genus Leucophenga (Diptera, Drosophilidae), part V: the mutabilis species group from East Asia, with morphological and molecular evidence. Zhou L, et al. Zootaxa, 2015 Aug 21. PMID 26623757

    See all (140) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables cytochrome-c oxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cytochrome-c oxidase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in aerobic respiration IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in electron transport coupled proton transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial electron transport, cytochrome c to oxygen IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial electron transport, cytochrome c to oxygen IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of mitochondrial respiratory chain complex IV IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of respiratory chain complex IV IC
    Inferred by Curator
    more info
    		 PubMed 
    part_of respiratory chain complex IV IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of respiratory chain complex IV IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cytochrome c oxidase subunit I
    YP_009047267.1
    • start codon not determined

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_024511.2 Reference assembly

      Range
      1474..3009
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_009047267.1 Peptide Sequence

      See identical proteins and their annotated locations for YP_009047267.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      B6E0P3, O21461, P00399, Q34349, Q6TXT7, Q7GFY7, Q7GHI7, Q9MGN6
      UniProtKB/TrEMBL
      A0A075E6K7, A0A0M4F7F6, A0A1S6KXC1, A0A1W6LRB8, J3T435, J7FKZ4
      Related
      FBpp0100176
      Conserved Domains (1) summary
      MTH00153
      Location:1 → 511
      COX1; cytochrome c oxidase subunit I; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P00399.2 P00399

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