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    Tagln transgelin [ Rattus norvegicus (Norway rat) ]

    Gene ID: 25123, updated on 30-Sep-2021

    Summary

    Official Symbol
    Taglnprovided by RGD
    Official Full Name
    transgelinprovided by RGD
    Primary source
    RGD:3723
    See related
    EnsemblRapid:ENSRNOG00000017628
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Sm22
    Summary
    acts as an actin cross-linking protein [RGD, Feb 2006]
    Expression
    Biased expression in Uterus (RPKM 5700.2), Lung (RPKM 1185.4) and 6 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Tagln in Genome Data Viewer
    Location:
    8q22
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    108 current mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (46224939..46230413, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (50222895..50228369, complement)

    Chromosome 8 - NC_051343.1Genomic Context describing neighboring genes Neighboring gene ring finger protein 214 Neighboring gene proprotein convertase subtilisin/kexin type 7 Neighboring gene uncharacterized LOC120094332 Neighboring gene SID1 transmembrane family, member 2 Neighboring gene platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 Neighboring gene 40S ribosomal protein S26-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables actin filament binding TAS
    Traceable Author Statement
    more info
    PubMed 
    enables protein-macromolecule adaptor activity TAS
    Traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    NOT acts_upstream_of_or_within cytoskeleton organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in epithelial cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in epithelial cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    transgelin
    Names
    SM22-alpha
    smooth muscle 22 protein
    smooth muscle protein 22-alpha

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_031549.2NP_113737.1  transgelin

      See identical proteins and their annotated locations for NP_113737.1

      Status: PROVISIONAL

      Source sequence(s)
      BC061770
      UniProtKB/Swiss-Prot
      P31232
      Related
      ENSRNOP00000069919.2, ENSRNOT00000081737.2
      Conserved Domains (2) summary
      pfam00402
      Location:175199
      Calponin; Calponin family repeat
      cd21279
      Location:23143
      CH_TAGLN; calponin homology (CH) domain found in transgelin

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mRatBN7.2 Primary Assembly

    Genomic

    1. NC_051343.1 Reference mRatBN7.2 Primary Assembly

      Range
      46224939..46230413 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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