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    GZMA granzyme A [ Pan troglodytes (chimpanzee) ]

    Gene ID: 461873, updated on 29-Mar-2024

    Summary

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    Official Symbol
    GZMAprovided by VGNC
    Official Full Name
    granzyme Aprovided by VGNC
    Primary source
    VGNC:VGNC:4023
    Locus tag
    CK820_G0045954
    See related
    Ensembl:ENSPTRG00000016871
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    See GZMA in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 4 NC_072402.2 (59551222..59558517, complement)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 5 NC_072403.1 (59980016..59987316, complement)

    Chromosome 4 - NC_072402.2Genomic Context describing neighboring genes Neighboring gene cell division cycle 20B Neighboring gene microRNA mir-449a Neighboring gene glutathione peroxidase 8 (putative) Neighboring gene uncharacterized LOC104006447 Neighboring gene granzyme K

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    granzyme A
    Names
    granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
    XP_001148261.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072402.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      59551222..59558517 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001148261.5 → XP_001148261.1  granzyme A

      See identical proteins and their annotated locations for XP_001148261.1

      UniProtKB/TrEMBL
      A0A2J8JMP1, A0A6D2X7L3, H2QQW5
      Related
      ENSPTRP00000028899.4
      Conserved Domains (1) summary
      cd00190
      Location:29 → 254
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    Nucleotide Protein
    Heading Accession and Version

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