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    185/333 Sp185/333 [ Strongylocentrotus purpuratus (purple sea urchin) ]

    Gene ID: 585345, updated on 18-Aug-2023

    Summary

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    Gene symbol
    185/333
    Gene description
    Sp185/333
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Strongylocentrotus purpuratus
    Lineage
    Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea; Euechinoidea; Echinacea; Camarodonta; Echinidea; Strongylocentrotidae; Strongylocentrotus
    Also known as
    Trf
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    Genomic context

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    Location:
    chromosome: Un
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    102 current Spur_5.0 (GCF_000002235.5) Unplaced Scaffold NW_022145545.1 (759692..761104)
    Build 3.1 previous assembly Spur_3.1 (GCF_000002235.3) Unplaced Scaffold NW_003577086.1 (507850..509262)

    NW_022145545.1Genomic Context describing neighboring genes Neighboring gene serine/threonine-protein phosphatase 1 regulatory subunit 10-like Neighboring gene serine/threonine-protein phosphatase 1 regulatory subunit 10-like Neighboring gene translation initiation factor IF-2-like Neighboring gene cubilin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Highly variable immune-response proteins (185/333) from the sea urchin, Strongylocentrotus purpuratus: proteomic analysis identifies diversity within and between individuals. Dheilly NM, et al. J Immunol, 2009 Feb 15. PMID 19201874
    2. Single sea urchin phagocytes express messages of a single sequence from the diverse Sp185/333 gene family in response to bacterial challenge. Majeske AJ, et al. J Immunol, 2014 Dec 1. PMID 25355922
    3. Distinctive expression patterns of 185/333 genes in the purple sea urchin, Strongylocentrotus purpuratus: an unexpectedly diverse family of transcripts in response to LPS, beta-1,3-glucan, and dsRNA. Terwilliger DP, et al. BMC Mol Biol, 2007 Mar 1. PMID 17331248, Free PMC Article
    4. Unexpected diversity displayed in cDNAs expressed by the immune cells of the purple sea urchin, Strongylocentrotus purpuratus. Terwilliger DP, et al. Physiol Genomics, 2006 Jul 12. PMID 16837652
    5. Gene structure in the sea urchin Strongylocentrotus purpuratus based on transcriptome analysis. Tu Q, et al. Genome Res, 2012 Oct. PMID 22709795, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. 185/333 proteins exhibit high levels of molecular diversity within and between individual sea urchins.
      Title: Highly variable immune-response proteins (185/333) from the sea urchin, Strongylocentrotus purpuratus: proteomic analysis identifies diversity within and between individuals.
    Submit: New GeneRIF Correction

    General protein information

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    Preferred Names
    185/333 family member
    Names
    185/333 E2
    DD185 protein, upregulated upon bacterial challenge and trauma

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001079548.1 → NP_001073016.1  185/333 family member precursor

      See identical proteins and their annotated locations for NP_001073016.1

      Status: PROVISIONAL

      Source sequence(s)
      DQ183181
      UniProtKB/TrEMBL
      Q3LS80, Q3LSA1, Q3LSA2
      Conserved Domains (1) summary
      pfam12782
      Location:1 → 290
      Innate_immun; Invertebrate innate immunity transcript family

    RefSeqs of Annotated Genomes: Strongylocentrotus purpuratus Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Spur_5.0 Primary Assembly

    Genomic

    1. NW_022145545.1 Reference Spur_5.0 Primary Assembly

      Range
      759692..761104
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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