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    arap2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 [ Acanthochromis polyacanthus (spiny chromis) ]

    Gene ID: 110955483, updated on 3-Apr-2024

    Summary

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    Gene symbol
    arap2
    Gene description
    ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
    See related
    Ensembl:ENSAPOG00000020105
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Acanthochromis polyacanthus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Pomacentridae; Acanthochromis
    Also known as
    zmp:0000000660
    Orthologs
    zebrafish all
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    Genomic context

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    Location:
    chromosome: 23
    Exon count:
    34
    Annotation release Status Assembly Chr Location
    RS_2023_02 current KAUST_Apoly_ChrSc (GCF_021347895.1) 23 NC_067135.1 (16891636..17112984, complement)

    Chromosome 23 - NC_067135.1Genomic Context describing neighboring genes Neighboring gene protocadherin 7b Neighboring gene uncharacterized LOC127532445 Neighboring gene death domain containing 1 Neighboring gene NACHT and WD repeat domain-containing protein 2 Neighboring gene uncharacterized LOC110962997

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_067135.1 Chromosome 23 Reference KAUST_Apoly_ChrSc

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol-3,4,5-trisphosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_021347895.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference KAUST_Apoly_ChrSc

    Genomic

    1. NC_067135.1 Reference KAUST_Apoly_ChrSc

      Range
      16891636..17112984 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_051944258.1 → XP_051800218.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2

    2. XM_022200496.2 → XP_022056188.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2

      UniProtKB/TrEMBL
      A0A3Q1GRQ0
      Related
      ENSAPOP00000032289.1
      Conserved Domains (6) summary
      cd04385
      Location:1089 → 1268
      RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
      pfam01412
      Location:664 → 768
      ArfGap; Putative GTPase activating protein for Arf
      cl15755
      Location:6 → 66
      SAM_superfamily; SAM (Sterile alpha motif )
      cl17171
      Location:1412 → 1517
      PH-like; Pleckstrin homology-like domain
      cl25424
      Location:1304 → 1395
      TGS; The TGS domain, named after the ThrRS, GTPase, and SpoT/RelA proteins where it occurs, is structurally similar to ubiquitin. TGS is a small domain of about 50 amino acid residues with a predominantly beta-sheet structure. There is no direct information ...
      cl26464
      Location:128 → 413
      Atrophin-1; Atrophin-1 family
    Nucleotide Protein
    Heading Accession and Version

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