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    LOC5576966 trypsin-1 [ Aedes aegypti (yellow fever mosquito) ]

    Gene ID: 5576966, updated on 23-Mar-2024

    Summary

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    Gene symbol
    LOC5576966
    Gene description
    trypsin-1
    See related
    VectorBase:AAEL003060
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Aedes aegypti
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae; Culicinae; Aedini; Aedes; Stegomyia
    Also known as
    CHYM; CHYM1; CHYM2; AAEL014188; AAEL801121
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    Genomic context

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    See LOC5576966 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    101 current AaegL5.0 (GCF_002204515.2) 2 NC_035108.1 (355319721..355320790)

    Chromosome 2 - NC_035108.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110676869 Neighboring gene uncharacterized LOC5563773 Neighboring gene nucleoporin nup124 Neighboring gene tyrosine-protein kinase Btk29A Neighboring gene uncharacterized LOC110676870 Neighboring gene dolichyl-phosphate beta-glucosyltransferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_035108.1 Chromosome 2 Reference AaegL5.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. cDNA cloning and pattern of expression of an adult, female-specific chymotrypsin from Aedes aegypti midgut. Jiang Q, et al. Insect Biochem Mol Biol, 1997 Apr. PMID 9134710
    2. Description of the transcriptomes of immune response-activated hemocytes from the mosquito vectors Aedes aegypti and Armigeres subalbatus. Bartholomay LC, et al. Infect Immun, 2004 Jul. PMID 15213157, Free PMC Article
    3. The neurotranscriptome of the Aedes aegypti mosquito. Matthews BJ, et al. BMC Genomics, 2016 Jan 6. PMID 26738925, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    trypsin-1
    Names
    chymotrypsin-like protease
    chymotrypsin-like protein
    female-specific chymotrypsin
    putative chymotrypsin-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Aedes aegypti Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference AaegL5.0 Primary Assembly

    Genomic

    1. NC_035108.1 Reference AaegL5.0 Primary Assembly

      Range
      355319721..355320790
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001663011.2 → XP_001663061.2  trypsin-1

      UniProtKB/TrEMBL
      A0A1S4F3L7, Q16H18, Q9BIG0
      Conserved Domains (1) summary
      cd00190
      Location:26 → 265
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    Nucleotide Protein Strain
    Heading Accession and Version

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