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    Fam107b family with sequence similarity 107, member B [ Mus musculus (house mouse) ]

    Gene ID: 66540, updated on 3-Apr-2024

    Summary

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    Official Symbol
    Fam107bprovided by MGI
    Official Full Name
    family with sequence similarity 107, member Bprovided by MGI
    Primary source
    MGI:MGI:1913790
    See related
    Ensembl:ENSMUSG00000026655 AllianceGenome:MGI:1913790
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    3110001A13Rik
    Summary
    Acts upstream of or within sensory perception of sound. Is expressed in renal interstitium; renal vasculature; and thymus primordium. Orthologous to human FAM107B (family with sequence similarity 107 member B). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in thymus adult (RPKM 16.4), testis adult (RPKM 14.5) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Fam107b in Genome Data Viewer
    Location:
    2 A1; 2 2.05 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (3705049..3783179)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (3704812..3782142)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 50615 Neighboring gene STARR-positive B cell enhancer ABC_E11701 Neighboring gene STARR-positive B cell enhancer ABC_E10078 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:3575227-3575425 Neighboring gene STARR-seq mESC enhancer starr_03517 Neighboring gene STARR-seq mESC enhancer starr_03518 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:3644924-3645077 Neighboring gene STARR-positive B cell enhancer ABC_E9192 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:3673208-3673317 Neighboring gene presenilin associated, rhomboid-like pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:3717012-3717165 Neighboring gene STARR-positive B cell enhancer ABC_E5881 Neighboring gene STARR-seq mESC enhancer starr_03521 Neighboring gene STARR-seq mESC enhancer starr_03522 Neighboring gene predicted gene, 36031 Neighboring gene STARR-seq mESC enhancer starr_03523 Neighboring gene FERM domain containing 4A Neighboring gene polypyrimidine tract-binding protein 1 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Deciphering the spatio-temporal expression and stress regulation of Fam107B, the paralog of the resilience-promoting protein DRR1 in the mouse brain. Masana M, et al. Neuroscience, 2015 Apr 2. PMID 25637808
    2. Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes. White JK, et al. Cell, 2013 Jul 18. PMID 23870131, Free PMC Article
    3. Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes. Bulfone A, et al. J Neurosci, 2005 Aug 17. PMID 16107646, Free PMC Article
    4. Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives. Tamplin OJ, et al. BMC Genomics, 2008 Oct 30. PMID 18973680, Free PMC Article
    5. Systematic analysis of human protein complexes identifies chromosome segregation proteins. Hutchins JR, et al. Science, 2010 Apr 30. PMID 20360068, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within sensory perception of sound IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    protein FAM107B
    Names
    novel DUF1151 domain containing protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001418244.1 → NP_001405173.1  protein FAM107B isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL732328, AL844530
      UniProtKB/Swiss-Prot
      Q3TGF2, Q9CR82
      Related
      ENSMUSP00000110705.3, ENSMUST00000115053.9

    2. NM_001418245.1 → NP_001405174.1  protein FAM107B isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL732328, AL844530

    3. NM_001418247.1 → NP_001405176.1  protein FAM107B isoform 3

      Status: VALIDATED

      Source sequence(s)
      AL844530

    4. NM_001418248.1 → NP_001405177.1  protein FAM107B isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL844530

    5. NM_001418250.1 → NP_001405179.1  protein FAM107B isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL732328, AL844530

    6. NM_001418252.1 → NP_001405181.1  protein FAM107B isoform 6

      Status: VALIDATED

      Source sequence(s)
      AL732328, AL844530
      Related
      ENSMUSP00000110704.3, ENSMUST00000115052.9

    7. NM_001418253.1 → NP_001405182.1  protein FAM107B isoform 7

      Status: VALIDATED

      Source sequence(s)
      AL732328, AL844530

    8. NM_025626.5 → NP_079902.1  protein FAM107B isoform 1

      See identical proteins and their annotated locations for NP_079902.1

      Status: VALIDATED

      Source sequence(s)
      AL732328, AL844530
      Consensus CDS
      CCDS15655.1
      UniProtKB/Swiss-Prot
      Q3TGF2, Q9CR82
      UniProtKB/TrEMBL
      H9H9T1
      Related
      ENSMUSP00000027965.5, ENSMUST00000027965.11
      Conserved Domains (1) summary
      pfam06625
      Location:8 → 120
      DUF1151; Protein of unknown function (DUF1151)

    RNA

    1. NR_184701.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL844530

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      3705049..3783179
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006497520.4 → XP_006497583.1  protein FAM107B isoform X3

      UniProtKB/TrEMBL
      H9H9T1
      Conserved Domains (1) summary
      pfam06625
      Location:37 → 148
      DUF1151; Protein of unknown function (DUF1151)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3TGF2.2 GenPept UniProtKB/Swiss-Prot:Q3TGF2

    Gene LinkOut

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