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    hpt hypoxanthine phosphoribosyltransferase [ Enterococcus faecium ]

    Gene ID: 66455492, updated on 3-Apr-2024

    Summary

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    Gene symbol
    hpt
    Gene description
    hypoxanthine phosphoribosyltransferase
    Locus tag
    E6A31_RS12460
    Gene type
    protein coding
    Organism
    Enterococcus faecium (strain: SRR24, nat-host: Homo sapiens)
    Lineage
    Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
    Old locus tag
    E6A31_13205
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    Genomic context

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    NZ_CP038996.1Genomic Context describing neighboring genes Neighboring gene Hsp33 family molecular chaperone HslO Neighboring gene ATP-dependent zinc metalloprotease FtsH Neighboring gene tRNA lysidine(34) synthetase TilS Neighboring gene S1 domain-containing RNA-binding protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NZ_CP038996.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Tigecycline resistance in clinical isolates of Enterococcus faecium is mediated by an upregulation of plasmid-encoded tetracycline determinants tet(L) and tet(M). Fiedler S, et al. J Antimicrob Chemother, 2016 Apr. PMID 26682961
    2. A single amino acid substitution in the human and a bacterial hypoxanthine phosphoribosyltransferase modulates specificity for the binding of guanine. Lee CC, et al. Biochemistry, 1998 Mar 10. PMID 9521670

    GeneRIFs: Gene References Into Functions

    General protein information

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    Preferred Names
    hypoxanthine phosphoribosyltransferase
    WP_002287415.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NZ_CP038996.1 Reference assembly

      Range
      2547542..2548087 complement
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      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_002287415.1 MULTISPECIES: hypoxanthine phosphoribosyltransferase [Enterococcus]

      See identical proteins and their annotated locations for WP_002287415.1

      UniProtKB/TrEMBL
      A0A132P685, A0A1E9VI32, A0A242DL96, A0A4Y3JPY0, A0A7W1XFH6, A0A829A2R6, A0A829F2T1, A0A829FGI5, A0A9P2S395, J7CVF9, Q3Y176, R2PDY6, U2NUT8
      Conserved Domains (1) summary
      COG0634
      Location:4 → 177
      HptA; Hypoxanthine-guanine phosphoribosyltransferase [Nucleotide transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version