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    Plbd2 phospholipase B domain containing 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 246120, updated on 2-Oct-2021

    Summary

    Official Symbol
    Plbd2provided by RGD
    Official Full Name
    phospholipase B domain containing 2provided by RGD
    Primary source
    RGD:708461
    See related
    EnsemblRapid:ENSRNOG00000001385
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    P76
    Summary
    human homolog is a nucleolar RNA-binding protein [RGD, Feb 2006]
    Expression
    Biased expression in Kidney (RPKM 242.2), Liver (RPKM 201.4) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Plbd2 in Genome Data Viewer
    Location:
    12q16
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    108 current mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (36062802..36081984)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (41600005..41619779)

    Chromosome 12 - NC_051347.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120095848 Neighboring gene two pore segment channel 1 Neighboring gene solute carrier family 8 member B1 Neighboring gene serine dehydratase Neighboring gene serine dehydratase-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables phospholipase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in phospholipid catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in extracellular region IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in lysosomal lumen IEA
    Inferred from Electronic Annotation
    more info
     
    located_in lysosome ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    putative phospholipase B-like 2
    Names
    LAMA-like protein 2
    RDCR-0918-3 protein
    lamina ancestor homolog 2
    mannose-6-phosphate protein p76
    phospholipase B domain-containing protein 2
    NP_640348.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_139255.3NP_640348.2  putative phospholipase B-like 2 precursor

      See identical proteins and their annotated locations for NP_640348.2

      Status: VALIDATED

      Source sequence(s)
      BC126078, DN935663, DY309487
      UniProtKB/Swiss-Prot
      Q4QQW8
      Related
      ENSRNOP00000001872.5, ENSRNOT00000001872.6
      Conserved Domains (1) summary
      pfam04916
      Location:77580
      Phospholip_B; Phospholipase B

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mRatBN7.2 Primary Assembly

    Genomic

    1. NC_051347.1 Reference mRatBN7.2 Primary Assembly

      Range
      36062802..36081984
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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