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    LOC1269914 pre-mRNA-processing factor 19 [ Anopheles gambiae (African malaria mosquito) ]

    Gene ID: 1269914, updated on 31-Jan-2024

    Summary

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    Gene symbol
    LOC1269914
    Gene description
    pre-mRNA-processing factor 19
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Anopheles gambiae
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae; Anophelinae; Anopheles
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2023_12 current idAnoGambNW_F1_1 (GCF_943734735.2) 2 NC_064601.1 (113146398..113154712)

    Chromosome 2 - NC_064601.1Genomic Context describing neighboring genes Neighboring gene ragulator complex protein LAMTOR2 homolog Neighboring gene dynein axonemal assembly factor 3 homolog Neighboring gene phosphoacetylglucosamine mutase Neighboring gene DE-cadherin Neighboring gene eukaryotic translation initiation factor 2 subunit 2 Neighboring gene uncharacterized LOC3290327 Neighboring gene uncharacterized LOC133395084

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_064601.1 Chromosome 2 Reference idAnoGambNW_F1_1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Anopheles gambiae genome: an update. Mongin E, et al. Trends Parasitol, 2004 Feb. PMID 14747013
    2. The genome sequence of the malaria mosquito Anopheles gambiae. Holt RA, et al. Science, 2002 Oct 4. PMID 12364791

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Prp19 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of U2-type catalytic step 1 spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pre-mRNA-processing factor 19

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_943734735.2-RS_2023_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference idAnoGambNW_F1_1 Primary Assembly

    Genomic

    1. NC_064601.1 Reference idAnoGambNW_F1_1 Primary Assembly

      Range
      113146398..113154712
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_061663682.1 → XP_061519666.1  pre-mRNA-processing factor 19

      UniProtKB/TrEMBL
      Q7PTA2

    2. XM_061663680.1 → XP_061519664.1  pre-mRNA-processing factor 19

      UniProtKB/TrEMBL
      Q7PTA2

    3. XM_308568.5 → XP_308568.4  pre-mRNA-processing factor 19

      See identical proteins and their annotated locations for XP_308568.4

      UniProtKB/TrEMBL
      Q7PTA2
      Conserved Domains (4) summary
      cd00200
      Location:209 → 501
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:224 → 262
      7WD40; WD40 repeat [structural motif]
      cd16656
      Location:4 → 56
      RING-Ubox_PRP19; U-box domain, a modified RING finger, found in pre-mRNA-processing factor 19 (Prp19) and similar proteins
      pfam08606
      Location:69 → 133
      Prp19; Prp19/Pso4-like
    Nucleotide Protein Strain
    Heading Accession and Version

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