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    Zeb1 zinc finger E-box binding homeobox 1 [ Mus musculus (house mouse) ]

    Gene ID: 21417, updated on 10-Mar-2024

    Summary

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    Official Symbol
    Zeb1provided by MGI
    Official Full Name
    zinc finger E-box binding homeobox 1provided by MGI
    Primary source
    MGI:MGI:1344313
    See related
    Ensembl:ENSMUSG00000024238 AllianceGenome:MGI:1344313
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tw; BZP; ZEB; MEB1; Nil2; Tcf8; AREB6; TCF-8; Tcf18; Zfhep; Zfx1a; Zfhx1a; Zfx1ha; [delta]EF1; 3110032K11Rik
    Summary
    Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; E-box binding activity; and chromatin binding activity. Involved in negative regulation of transcription, DNA-templated and positive regulation of neuron differentiation. Acts upstream of or within several processes, including embryonic organ morphogenesis; regulation of T cell differentiation in thymus; and regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; embryo mesoderm; and genitourinary system. Used to study tropical spastic paraparesis. Human ortholog(s) of this gene implicated in Fuchs' endothelial dystrophy and posterior polymorphous corneal dystrophy 3. Orthologous to human ZEB1 (zinc finger E-box binding homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 9.2), limb E14.5 (RPKM 8.6) and 26 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Zeb1 in Genome Data Viewer
    Location:
    18 4.42 cM; 18 A1
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (5591330..5775468)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (5591327..5775468)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_43695 Neighboring gene predicted gene, 34630 Neighboring gene STARR-seq mESC enhancer starr_43697 Neighboring gene zinc finger E-box binding homeobox 1, opposite strand 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr18:5591157-5591340 Neighboring gene STARR-positive B cell enhancer mm9_chr18:5591593-5591893 Neighboring gene predicted gene, 52340 Neighboring gene predicted gene 2238 Neighboring gene STARR-seq mESC enhancer starr_43699 Neighboring gene predicted gene, 34740 Neighboring gene predicted gene, 34804

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Ploidy-stratified single cardiomyocyte transcriptomics map Zinc Finger E-Box Binding Homeobox 1 to underly cardiomyocyte proliferation before birth. Bak ST, et al. Basic Res Cardiol, 2023 Mar 2. PMID 36862248, Free PMC Article
    2. Zeb1 sustains hematopoietic stem cell functions by suppressing mitofusin-2-mediated mitochondrial fusion. Zhang K, et al. Cell Death Dis, 2022 Aug 25. PMID 36008379, Free PMC Article
    3. Pro-angiogenic role of ZEB1 in skin wound healing by upregulating VEGFA via microRNA-206 suppression. Lan H, et al. Exp Dermatol, 2022 Sep. PMID 35570385
    4. Zeb1 regulation of wound-healing-induced inflammation in alkali-damaged corneas. Liang W, et al. iScience, 2022 Apr 15. PMID 35340433, Free PMC Article
    5. Zeb1 modulates hematopoietic stem cell fates required for suppressing acute myeloid leukemia. Almotiri A, et al. J Clin Invest, 2021 Jan 4. PMID 33108352, Free PMC Article

    See all (208) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. ZEB1 shapes AML immunological niches, suppressing CD8 T cell activity while fostering Th17 cell expansion.
      Title: ZEB1 shapes AML immunological niches, suppressing CD8 T cell activity while fostering Th17 cell expansion.
    2. Atherosclerotic plaque development in mice is enhanced by myeloid ZEB1 downregulation.
      Title: Atherosclerotic plaque development in mice is enhanced by myeloid ZEB1 downregulation.
    3. The adaptive antioxidant response during fasting-induced muscle atrophy is oppositely regulated by ZEB1 and ZEB2.
      Title: The adaptive antioxidant response during fasting-induced muscle atrophy is oppositely regulated by ZEB1 and ZEB2.
    4. PRMT1 accelerates cell proliferation, migration, and tumor growth by upregulating ZEB1/H4R3me2as in thyroid carcinoma.
      Title: PRMT1 accelerates cell proliferation, migration, and tumor growth by upregulating ZEB1/H4R3me2as in thyroid carcinoma.
    5. The transcription factor Zeb1 controls homeostasis and function of type 1 conventional dendritic cells.
      Title: The transcription factor Zeb1 controls homeostasis and function of type 1 conventional dendritic cells.
    6. LncRNA LINC00667 gets involved in clear cell renal cell carcinoma development and chemoresistance by regulating the miR-143-3p/ZEB1 axis.
      Title: LncRNA LINC00667 gets involved in clear cell renal cell carcinoma development and chemoresistance by regulating the miR-143-3p/ZEB1 axis.
    7. ZEB1 Transcriptionally Activates PHGDH to Facilitate Carcinogenesis and Progression of HCC.
      Title: ZEB1 Transcriptionally Activates PHGDH to Facilitate Carcinogenesis and Progression of HCC.
    8. Metabolic stress-induced reciprocal loop of long noncoding RNA ZFAS1 and ZEB1 promotes epithelial-mesenchymal transition and metastasis of pancreatic cancer cells.
      Title: Metabolic stress-induced reciprocal loop of long noncoding RNA ZFAS1 and ZEB1 promotes epithelial-mesenchymal transition and metastasis of pancreatic cancer cells.
    9. CUL4A-mediated ZEB1/microRNA-340-5p/HMGB1 axis promotes the development of osteoporosis.
      Title: CUL4A-mediated ZEB1/microRNA-340-5p/HMGB1 axis promotes the development of osteoporosis.
    10. A Zeb1/MtCK1 metabolic axis controls osteoclast activation and skeletal remodeling.
      Title: A Zeb1/MtCK1 metabolic axis controls osteoclast activation and skeletal remodeling.
    Submit: New GeneRIF Correction See all GeneRIFs (113)

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription repressor activity, RNA polymerase II-specific ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables E-box binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables chromatin binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables chromatin binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in anatomical structure development IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within animal organ development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cartilage development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of cell population proliferation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cellular response to amino acid stimulus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within central nervous system development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within cochlea morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within embryonic camera-type eye morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within embryonic morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within embryonic skeletal system morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of epithelial cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of keratinocyte proliferation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in negative regulation of DNA-templated transcription ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of endothelial cell differentiation ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within negative regulation of epithelial cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of epithelial cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of keratinocyte proliferation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within pattern specification process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of neuron differentiation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within regulation of T cell differentiation in thymus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of mesenchymal cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of smooth muscle cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within regulation of transforming growth factor beta receptor signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within semicircular canal morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger E-box-binding homeobox 1
    Names
    transcription factor 8
    twirler
    zinc finger homeobox protein 1a

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001360981.1 → NP_001347910.1  zinc finger E-box-binding homeobox 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC127028, AC138619
      UniProtKB/TrEMBL
      A4QPD1
      Conserved Domains (4) summary
      smart00389
      Location:554 → 590
      HOX; Homeodomain
      sd00017
      Location:867 → 887
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:203 → 225
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:907 → 932
      zf-H2C2_2; Zinc-finger double domain

    2. NM_001360982.1 → NP_001347911.1  zinc finger E-box-binding homeobox 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC127028, AC138619
      UniProtKB/TrEMBL
      A4QPD1
      Conserved Domains (3) summary
      sd00017
      Location:828 → 848
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:164 → 186
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:868 → 893
      zf-H2C2_2; Zinc-finger double domain

    3. NM_011546.3 → NP_035676.1  zinc finger E-box-binding homeobox 1 isoform 1

      See identical proteins and their annotated locations for NP_035676.1

      Status: VALIDATED

      Source sequence(s)
      AC127028, AK034821, BC139769, BE852657
      Consensus CDS
      CCDS29039.1
      UniProtKB/Swiss-Prot
      A4QPD2, Q62519, Q64318
      UniProtKB/TrEMBL
      A4QPD1
      Related
      ENSMUSP00000025081.6, ENSMUST00000025081.13
      Conserved Domains (4) summary
      smart00389
      Location:571 → 607
      HOX; Homeodomain
      sd00017
      Location:884 → 904
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:220 → 242
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:924 → 949
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      5591330..5775468
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030250410.2 → XP_030106270.1  zinc finger E-box-binding homeobox 1 isoform X3

      UniProtKB/TrEMBL
      A4QPD1
      Conserved Domains (3) summary
      sd00017
      Location:828 → 848
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:164 → 186
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:868 → 893
      zf-H2C2_2; Zinc-finger double domain

    2. XM_030250409.2 → XP_030106269.1  zinc finger E-box-binding homeobox 1 isoform X3

      UniProtKB/TrEMBL
      A4QPD1
      Conserved Domains (3) summary
      sd00017
      Location:828 → 848
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:164 → 186
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:868 → 893
      zf-H2C2_2; Zinc-finger double domain

    3. XM_030250411.2 → XP_030106271.1  zinc finger E-box-binding homeobox 1 isoform X4

      UniProtKB/TrEMBL
      A4QPD1
      Conserved Domains (4) summary
      smart00389
      Location:504 → 540
      HOX; Homeodomain
      sd00017
      Location:817 → 837
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:153 → 175
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:857 → 882
      zf-H2C2_2; Zinc-finger double domain

    4. XM_036161065.1 → XP_036016958.1  zinc finger E-box-binding homeobox 1 isoform X3

      UniProtKB/TrEMBL
      A4QPD1
      Conserved Domains (3) summary
      sd00017
      Location:828 → 848
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:164 → 186
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:868 → 893
      zf-H2C2_2; Zinc-finger double domain

    5. XM_030250401.1 → XP_030106261.1  zinc finger E-box-binding homeobox 1 isoform X1

      UniProtKB/TrEMBL
      A4QPD1
      Conserved Domains (3) summary
      sd00017
      Location:877 → 897
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:213 → 235
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:917 → 942
      zf-H2C2_2; Zinc-finger double domain

    6. XM_030250405.2 → XP_030106265.1  zinc finger E-box-binding homeobox 1 isoform X3

      UniProtKB/TrEMBL
      A4QPD1
      Conserved Domains (3) summary
      sd00017
      Location:828 → 848
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:164 → 186
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:868 → 893
      zf-H2C2_2; Zinc-finger double domain

    7. XM_030250400.2 → XP_030106260.1  zinc finger E-box-binding homeobox 1 isoform X1

      UniProtKB/TrEMBL
      A4QPD1
      Conserved Domains (3) summary
      sd00017
      Location:877 → 897
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:213 → 235
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:917 → 942
      zf-H2C2_2; Zinc-finger double domain

    8. XM_030250406.2 → XP_030106266.1  zinc finger E-box-binding homeobox 1 isoform X3

      UniProtKB/TrEMBL
      A4QPD1
      Conserved Domains (3) summary
      sd00017
      Location:828 → 848
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:164 → 186
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:868 → 893
      zf-H2C2_2; Zinc-finger double domain

    9. XM_036161061.1 → XP_036016954.1  zinc finger E-box-binding homeobox 1 isoform X1

      UniProtKB/TrEMBL
      A4QPD1
      Conserved Domains (3) summary
      sd00017
      Location:877 → 897
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:213 → 235
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:917 → 942
      zf-H2C2_2; Zinc-finger double domain

    10. XM_006525769.4 → XP_006525832.1  zinc finger E-box-binding homeobox 1 isoform X1

      See identical proteins and their annotated locations for XP_006525832.1

      UniProtKB/TrEMBL
      A4QPD1
      Conserved Domains (3) summary
      sd00017
      Location:877 → 897
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:213 → 235
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:917 → 942
      zf-H2C2_2; Zinc-finger double domain

    11. XM_036161062.1 → XP_036016955.1  zinc finger E-box-binding homeobox 1 isoform X3

      UniProtKB/TrEMBL
      A4QPD1
      Conserved Domains (3) summary
      sd00017
      Location:828 → 848
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:164 → 186
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:868 → 893
      zf-H2C2_2; Zinc-finger double domain

    12. XM_036161059.1 → XP_036016952.1  zinc finger E-box-binding homeobox 1 isoform X1

      UniProtKB/TrEMBL
      A4QPD1
      Conserved Domains (3) summary
      sd00017
      Location:877 → 897
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:213 → 235
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:917 → 942
      zf-H2C2_2; Zinc-finger double domain

    13. XM_030250407.2 → XP_030106267.1  zinc finger E-box-binding homeobox 1 isoform X3

      UniProtKB/TrEMBL
      A4QPD1
      Conserved Domains (3) summary
      sd00017
      Location:828 → 848
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:164 → 186
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:868 → 893
      zf-H2C2_2; Zinc-finger double domain

    14. XM_030250404.2 → XP_030106264.1  zinc finger E-box-binding homeobox 1 isoform X3

      UniProtKB/TrEMBL
      A4QPD1
      Conserved Domains (3) summary
      sd00017
      Location:828 → 848
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:164 → 186
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:868 → 893
      zf-H2C2_2; Zinc-finger double domain

    15. XM_036161068.1 → XP_036016961.1  zinc finger E-box-binding homeobox 1 isoform X3

      UniProtKB/TrEMBL
      A4QPD1
      Conserved Domains (3) summary
      sd00017
      Location:828 → 848
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:164 → 186
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:868 → 893
      zf-H2C2_2; Zinc-finger double domain

    16. XM_036161067.1 → XP_036016960.1  zinc finger E-box-binding homeobox 1 isoform X3

      UniProtKB/TrEMBL
      A4QPD1
      Conserved Domains (3) summary
      sd00017
      Location:828 → 848
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:164 → 186
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:868 → 893
      zf-H2C2_2; Zinc-finger double domain

    17. XM_030250402.2 → XP_030106262.1  zinc finger E-box-binding homeobox 1 isoform X2

      UniProtKB/TrEMBL
      A4QPD1
      Conserved Domains (4) summary
      smart00389
      Location:557 → 593
      HOX; Homeodomain
      sd00017
      Location:870 → 890
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:206 → 228
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:910 → 935
      zf-H2C2_2; Zinc-finger double domain

    18. XM_030250399.2 → XP_030106259.1  zinc finger E-box-binding homeobox 1 isoform X1

      UniProtKB/TrEMBL
      A4QPD1
      Conserved Domains (3) summary
      sd00017
      Location:877 → 897
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:213 → 235
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:917 → 942
      zf-H2C2_2; Zinc-finger double domain

    19. XM_036161066.1 → XP_036016959.1  zinc finger E-box-binding homeobox 1 isoform X3

      UniProtKB/TrEMBL
      A4QPD1
      Conserved Domains (3) summary
      sd00017
      Location:828 → 848
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:164 → 186
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:868 → 893
      zf-H2C2_2; Zinc-finger double domain

    20. XM_036161069.1 → XP_036016962.1  zinc finger E-box-binding homeobox 1 isoform X3

      UniProtKB/TrEMBL
      A4QPD1
      Conserved Domains (3) summary
      sd00017
      Location:828 → 848
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:164 → 186
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:868 → 893
      zf-H2C2_2; Zinc-finger double domain

    21. XM_036161063.1 → XP_036016956.1  zinc finger E-box-binding homeobox 1 isoform X3

      UniProtKB/TrEMBL
      A4QPD1
      Conserved Domains (3) summary
      sd00017
      Location:828 → 848
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:164 → 186
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:868 → 893
      zf-H2C2_2; Zinc-finger double domain

    22. XM_036161064.1 → XP_036016957.1  zinc finger E-box-binding homeobox 1 isoform X3

      UniProtKB/TrEMBL
      A4QPD1
      Conserved Domains (3) summary
      sd00017
      Location:828 → 848
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:164 → 186
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:868 → 893
      zf-H2C2_2; Zinc-finger double domain

    23. XM_036161070.1 → XP_036016963.1  zinc finger E-box-binding homeobox 1 isoform X3

      UniProtKB/TrEMBL
      A4QPD1
      Conserved Domains (3) summary
      sd00017
      Location:828 → 848
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:164 → 186
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:868 → 893
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q64318.1 GenPept UniProtKB/Swiss-Prot:Q64318

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