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    Lmnb1 lamin B1 [ Mus musculus (house mouse) ]

    Gene ID: 16906, updated on 25-Nov-2021

    Summary

    Official Symbol
    Lmnb1provided by MGI
    Official Full Name
    lamin B1provided by MGI
    Primary source
    MGI:MGI:96795
    See related
    Ensembl:ENSMUSG00000024590
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Expression
    Broad expression in CNS E11.5 (RPKM 89.9), thymus adult (RPKM 41.9) and 17 other tissues See more
    Orthologs
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    Genomic context

    See Lmnb1 in Genome Data Viewer
    Location:
    18 D3; 18 30.84 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (56840885..56886496)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (56707813..56753424)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (56867467..56913078)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 50288 Neighboring gene predicted gene, 41738 Neighboring gene membrane associated ring-CH-type finger 3 Neighboring gene predicted gene 15345 Neighboring gene VISTA enhancer mm109

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables JUN kinase binding NAS
    Non-traceable Author Statement
    more info
    PubMed 
    enables double-stranded DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables phospholipase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables sequence-specific double-stranded DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in intermediate filament IEA
    Inferred from Electronic Annotation
    more info
     
    located_in lamin filament IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nuclear envelope IDA
    Inferred from Direct Assay
    more info
    PubMed 
    colocalizes_with nuclear envelope ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear envelope ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear envelope TAS
    Traceable Author Statement
    more info
     
    located_in nuclear inner membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nuclear lamina ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear matrix IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nuclear matrix ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010721.2NP_034851.2  lamin-B1

      See identical proteins and their annotated locations for NP_034851.2

      Status: VALIDATED

      Source sequence(s)
      AK132252, BC052729
      Consensus CDS
      CCDS29261.1
      UniProtKB/Swiss-Prot
      P14733
      Related
      ENSMUSP00000025486.9, ENSMUST00000025486.9
      Conserved Domains (2) summary
      pfam00038
      Location:32388
      Filament; Intermediate filament protein
      pfam00932
      Location:440544
      LTD; Lamin Tail Domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      56840885..56886496
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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