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    Snx16 Sorting nexin 16 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37015, updated on 10-May-2024

    Summary

    Official Symbol
    Snx16provided by FlyBase
    Official Full Name
    Sorting nexin 16provided by FlyBase
    Primary source
    FLYBASE:FBgn0034265
    Locus tag
    Dmel_CG6410
    See related
    AllianceGenome:FB:FBgn0034265
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG6410; Dmel\CG6410; DmSNX16; dSnx16; snx16; SNX16
    Summary
    Predicted to enable phosphatidylinositol binding activity. Involved in positive regulation of synaptic assembly at neuromuscular junction and receptor recycling. Located in early endosome; multivesicular body; and neuromuscular junction. Is expressed in adult head and organism. Orthologous to human SNX16 (sorting nexin 16). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See Snx16 in Genome Data Viewer
    Location:
    54E2-54E2; 2-84 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (17725030..17726847, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (13612535..13614352, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene U snoRNA host gene 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Dachs ligand with SH3s Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene hyccin

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables phosphatidylinositol binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables phosphatidylinositol binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphatidylinositol binding ISM
    Inferred from Sequence Model
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in early endosome to late endosome transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in endosome to lysosome transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of synaptic assembly at neuromuscular junction IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in protein targeting to lysosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in receptor recycling IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in early endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in early endosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in late endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in multivesicular body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in neuromuscular junction IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in presynaptic endosome IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    sorting nexin 16
    Names
    CG6410-PA
    Snx16-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      17725030..17726847 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137408.4NP_611252.1  sorting nexin 16 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611252.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7JR96
      Related
      FBpp0086045
      Conserved Domains (1) summary
      cd07276
      Location:219329
      PX_SNX16; The phosphoinositide binding Phox Homology domain of Sorting Nexin 16