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    Obp19b Odorant-binding protein 19b [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33038, updated on 10-May-2024

    Summary

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    Official Symbol
    Obp19bprovided by FlyBase
    Official Full Name
    Odorant-binding protein 19bprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031110
    Locus tag
    Dmel_CG1670
    See related
    AllianceGenome:FB:FBgn0031110
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    19b; anon-WO0140519.23; CG1670; DmelObp19b; Dmel\CG1670; o19b; OBP19b
    Summary
    Enables amino acid binding activity. Involved in sensory perception of taste. Predicted to be located in extracellular region. Is expressed in anterior wing margin; labellum; and leg taste bristle. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See Obp19b in Genome Data Viewer
    Location:
    19D1-19D1; 1-64 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (20416733..20417812)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (20287760..20288839)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Odorant-binding protein 19a Neighboring gene Odorant-binding protein 19c Neighboring gene Odorant-binding protein 19d

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Y not a dead end: epistatic interactions between Y-linked regulatory polymorphisms and genetic background affect global gene expression in Drosophila melanogaster. Jiang PP, et al. Genetics, 2010 Sep. PMID 20551438, Free PMC Article
    2. Novel odorant-binding proteins expressed in the taste tissue of the fly. Koganezawa M, et al. Chem Senses, 2002 May. PMID 12006372
    3. Natural variation, functional pleiotropy and transcriptional contexts of odorant binding protein genes in Drosophila melanogaster. Arya GH, et al. Genetics, 2010 Dec. PMID 20870963, Free PMC Article
    4. A conserved odorant binding protein is required for essential amino acid detection in Drosophila. Rihani K, et al. Commun Biol, 2019. PMID 31799428, Free PMC Article
    5. An odorant-binding protein required for suppression of sweet taste by bitter chemicals. Jeong YT, et al. Neuron, 2013 Aug 21. PMID 23972598, Free PMC Article

    See all (41) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables amino acid binding IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables odorant binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables odorant binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in sensory perception of chemical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in sensory perception of smell IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sensory perception of taste IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Odorant-binding protein 19b
    Names
    CG1670-PA
    Obp19b-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      20416733..20417812
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_134547.3 → NP_608391.2  Odorant-binding protein 19b [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608391.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      E2DB82, E2DBB0, E2DBD7, E2DBD8, E2DBF4, Q8SY63, Q9VR95
      Related
      FBpp0076994
      Conserved Domains (1) summary
      pfam01395
      Location:38 → 150
      PBP_GOBP; PBP/GOBP family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VR95 Q9VR95

    Gene LinkOut

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