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    CXCL2 chemokine (C-X-C motif) ligand 2 [ Bos taurus (cattle) ]

    Gene ID: 281214, updated on 16-Jan-2024

    Summary

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    Gene symbol
    CXCL2
    Gene description
    chemokine (C-X-C motif) ligand 2
    See related
    BGD:BT10740; Ensembl:ENSBTAG00000027513
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    GRO3
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    Genomic context

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    Location:
    chromosome: 6
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 6 NC_037333.1 (88946394..88948465)

    Chromosome 6 - NC_037333.1Genomic Context describing neighboring genes Neighboring gene pro-platelet basic protein Neighboring gene platelet factor 4 Neighboring gene uncharacterized LOC100847175 Neighboring gene uncharacterized LOC101906736

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037333.1 Chromosome 6 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Single nucleotide polymorphism (SNP) discovery and linkage mapping of bovine cytokine genes. Grosse WM, et al. Mamm Genome, 1999 Nov. PMID 10556424
    2. Isolation of novel GRO genes and a phylogenetic analysis of the CXC chemokine subfamily in mammals. Modi WS, et al. Mol Biol Evol, 1999 Feb. PMID 10028286
    3. Assignment of the mouse and cow CXC chemokine genes. Modi WS, et al. Cytogenet Cell Genet, 1998. PMID 9730606

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables CXCR chemokine receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables chemokine activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in antimicrobial humoral immune response mediated by antimicrobial peptide IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to lipopolysaccharide IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in chemokine-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neutrophil chemotaxis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    growth-regulated protein homolog gamma
    Names
    GRO-gamma
    GRO3 oncogene
    GRO3, growth related gene 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174299.3 → NP_776724.1  growth-regulated protein homolog gamma precursor

      See identical proteins and their annotated locations for NP_776724.1

      Status: PROVISIONAL

      Source sequence(s)
      U95811
      UniProtKB/Swiss-Prot
      O46675
      Related
      ENSBTAP00000039327.3, ENSBTAT00000039536.4
      Conserved Domains (1) summary
      cd00273
      Location:36 → 98
      Chemokine_CXC; Chemokine_CXC: 1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; many members ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037333.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      88946394..88948465
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005208062.5 → XP_005208119.1  growth-regulated protein homolog gamma isoform X1

      See identical proteins and their annotated locations for XP_005208119.1

      UniProtKB/Swiss-Prot
      O46675
      Conserved Domains (1) summary
      cd00273
      Location:36 → 98
      Chemokine_CXC; Chemokine_CXC: 1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; many members ...
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O46675.1 GenPept UniProtKB/Swiss-Prot:O46675

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