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    LBRM_27_2690 conserved hypothetical protein [ Leishmania braziliensis MHOM/BR/75/M2904 ]

    Gene ID: 5416889, updated on 28-Dec-2023

    Summary

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    Gene symbol
    LBRM_27_2690
    Gene description
    conserved hypothetical protein
    Locus tag
    LBRM_27_2690
    Gene type
    protein coding
    RNA name
    conserved hypothetical protein
    RefSeq status
    PROVISIONAL
    Organism
    Leishmania braziliensis MHOM/BR/75/M2904 (strain: MHOM/BR/75/M2904)
    Lineage
    Eukaryota; Euglenozoa; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania braziliensis species complex
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    Genomic context

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    Location:
    chromosome: 27
    Exon count:
    1
    Sequence:
    Chromosome: 27; NC_009319.2 (1043909..1045459)

    Chromosome 27 - NC_009319.2Genomic Context describing neighboring genes Neighboring gene putative protein kinase Neighboring gene putative protein kinase Neighboring gene tubulin-tyrosine ligase-like protein Neighboring gene putative dynein heavy chain

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009319.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Comparative genomic analysis of three Leishmania species that cause diverse human disease. Peacock CS, et al. Nat Genet, 2007 Jul. PMID 17572675, Free PMC Article
    2. Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania. Rogers MB, et al. Genome Res, 2011 Dec. PMID 22038252, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Prp19 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of U2-type catalytic step 1 spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Names
    conserved hypothetical protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_009319.2 Reference assembly

      Range
      1043909..1045459
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001565972.2 → XP_001566022.2  conserved hypothetical protein [Leishmania braziliensis MHOM/BR/75/M2904]

      See identical proteins and their annotated locations for XP_001566022.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A3P3ZAA2, A4HG28
      Conserved Domains (5) summary
      COG2319
      Location:226 → 515
      WD40; WD40 repeat [General function prediction only]
      pfam08606
      Location:72 → 131
      Prp19; Prp19/Pso4-like
      sd00039
      Location:258 → 293
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:247 → 510
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cl17238
      Location:1 → 52
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    Nucleotide Protein
    Heading Accession and Version

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