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    CSN1S1 casein alpha s1 [ Ovis aries (sheep) ]

    Gene ID: 443382, updated on 5-Mar-2024

    Summary

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    Gene symbol
    CSN1S1
    Gene description
    casein alpha s1
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Ovis aries
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 6
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 6 NC_056059.1 (86175191..86191920)

    Chromosome 6 - NC_056059.1Genomic Context describing neighboring genes Neighboring gene sulfotransferase 1E1 Neighboring gene transfer RNA histidin (anticodon GUG) Neighboring gene casein beta Neighboring gene uncharacterized LOC114115417

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056059.1 Chromosome 6 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Short communication: molecular genetic characterization of ovine alpha(S1)-casein allele H caused by alternative splicing. Giambra IJ, et al. J Dairy Sci, 2010 Feb. PMID 20105551
    2. Primary structure of ovine alpha s1-caseins: localization of phosphorylation sites and characterization of genetic variants A, C and D. Ferranti P, et al. J Dairy Res, 1995 May. PMID 7601973
    3. Construction and identification of recombinant plasmids carrying cDNAs coding for ovine alpha S1-, alpha S2-, beta-, kappa-casein and beta-lactoglobulin. Nucleotide sequence of alpha S1-casein cDNA. Mercier JC, et al. Biochimie, 1985 Sep. PMID 3002501
    4. Single nucleotide polymorphisms in the ovine casein genes detected by polymerase chain reaction-single strand conformation polymorphism. Ceriotti G, et al. J Dairy Sci, 2004 Aug. PMID 15328285

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in response to 11-deoxycorticosterone IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to dehydroepiandrosterone IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to estradiol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to progesterone IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    alpha-S1-casein
    Names
    alfas1-casein
    alpha s1 casein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001009795.1 → NP_001009795.1  alpha-S1-casein precursor

      See identical proteins and their annotated locations for NP_001009795.1

      Status: PROVISIONAL

      Source sequence(s)
      X03237
      UniProtKB/TrEMBL
      D2D3I8
      Conserved Domains (1) summary
      pfam00363
      Location:114 → 179
      Casein; Casein

    RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Genomic

    1. NC_056059.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

      Range
      86175191..86191920
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012179357.5 → XP_012034747.1  alpha-S1-casein isoform X1

      See identical proteins and their annotated locations for XP_012034747.1

      UniProtKB/TrEMBL
      A0A6P3TSW7, D2D3I8, G3LUQ4
      Conserved Domains (1) summary
      pfam00363
      Location:114 → 187
      Casein; Casein
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P04653.3 GenPept UniProtKB/Swiss-Prot:P04653

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