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    CPE carboxypeptidase E [ Gallus gallus (chicken) ]

    Gene ID: 422424, updated on 5-Mar-2024

    Summary

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    Symbol
    CPEprovided by CGNC
    Full Name
    carboxypeptidase Eprovided by CGNC
    Primary source
    CGNC:66432
    See related
    Ensembl:ENSGALG00010007882
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See CPE in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 4 NC_052535.1 (23337542..23384245)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 4 NC_052576.1 (23403746..23450530)

    Chromosome 4 - NC_052535.1Genomic Context describing neighboring genes Neighboring gene kelch like family member 2 Neighboring gene uncharacterized LOC121110790 Neighboring gene methylsterol monooxygenase 1 Neighboring gene uncharacterized LOC107052719 Neighboring gene serine/arginine repetitive matrix protein 3-like Neighboring gene tolloid like 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Carboxypeptidase E, an essential element of the regulated secretory pathway, is expressed and partially co-localized with chromogranin A in chicken thymus. Zhang X, et al. Cell Tissue Res, 2009 Sep. PMID 19603184, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. co-existence of CgA and CpE in identical neuroendocrine cells in the transition zone between the cortex and medulla of the thymus
      Title: Carboxypeptidase E, an essential element of the regulated secretory pathway, is expressed and partially co-localized with chromogranin A in chicken thymus.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metallocarboxypeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    carboxypeptidase E
    XP_040527749.1
    XP_046772890.1
    XP_046796521.1
    XP_420392.3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      23337542..23384245
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_420392.8 → XP_420392.3  carboxypeptidase E isoform X1

      UniProtKB/TrEMBL
      R4GFJ0
      Related
      ENSGALP00010010303.1, ENSGALT00010018753.1
      Conserved Domains (2) summary
      cd11308
      Location:368 → 442
      Peptidase_M14NE-CP-C_like; Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain
      cd03865
      Location:46 → 364
      M14_CPE; Peptidase M14 carboxypeptidase subfamily N/E-like; Carboxypeptidase E subgroup

    2. XM_046940565.1 → XP_046796521.1  carboxypeptidase E isoform X2

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052576.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      23403746..23450530
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040671815.2 → XP_040527749.1  carboxypeptidase E isoform X1

      UniProtKB/TrEMBL
      R4GFJ0
      Conserved Domains (2) summary
      cd11308
      Location:368 → 442
      Peptidase_M14NE-CP-C_like; Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain
      cd03865
      Location:46 → 364
      M14_CPE; Peptidase M14 carboxypeptidase subfamily N/E-like; Carboxypeptidase E subgroup

    2. XM_046916934.1 → XP_046772890.1  carboxypeptidase E isoform X2

    Nucleotide Protein
    Heading Accession and Version

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