Obp83a Odorant-binding protein 83a [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Obp83aprovided by FlyBase
Official Full Name: Odorant-binding protein 83aprovided by FlyBase
Primary source: FLYBASE:FBgn0011281
Locus tag: Dmel_CG11421
See related: AllianceGenome:FB:FBgn0011281
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: 83a; CG11421; DmelObp83a; Dmel\CG11421; Obp33a; obp83a; OBP83a; Os-F; OS-F; OS-F/PBP3; PB-PRP3; PBP-H2; pbprp-3; PBPRP-3; pbprp3; Pbprp3; PBPRP3; pbprp3(OS-F)
Summary: Predicted to enable pheromone binding activity. Predicted to be involved in sensory perception of smell. Predicted to be located in extracellular region. Is expressed in antenna; antennal sense organ; and eo support cell. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (5972155..5975245, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (1797877..1800967, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Odorant activation kinetics is not altered in null mutants. Unexpected phenotype associated with the null mutation implicates Obp83a in the deactivation of odorant responses. Obp83a is functionally redundant.
Title: Odor-Specific Deactivation Defects in a Drosophila Odorant-Binding Protein Mutant.
Positive selection was likely involved in the functional diversification of the OS-E and OS-F genes after the gene duplication event.
Title: Divergent evolution and molecular adaptation in the Drosophila odorant-binding protein family: inferences from sequence variation at the OS-E and OS-F genes.
determination of presence in variety of drosophila species
Title: Patterns of nucleotide polymorphism and divergence in the odorant-binding protein genes OS-E and OS-F: analysis in the melanogaster species subgroup of Drosophila.

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables odorant binding	IEA Inferred from Electronic Annotation more info
enables odorant binding	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables pheromone binding	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
involved_in sensory perception of chemical stimulus	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in sensory perception of smell	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in extracellular region	ISM Inferred from Sequence Model more info	PubMed

Names: CG11421-PA; CG11421-PB; CG11421-PC; Obp83a-PA; Obp83a-PB; Obp83a-PC; Olfactory-specific-F; Pbprp3; Pheromone-binding protein homolog 2; Pheromone-binding protein-related protein 3

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The following sections contain reference sequences that belong to a specific genome build. Explain