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    MYH10 myosin, heavy chain 10, non-muscle [ Gallus gallus (chicken) ]

    Gene ID: 396465, updated on 3-Apr-2024

    Summary

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    Official Symbol
    MYH10provided by CGNC
    Official Full Name
    myosin, heavy chain 10, non-muscleprovided by CGNC
    Primary source
    CGNC:49817
    See related
    Ensembl:ENSGALG00010029349
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    myosin; myosin-10; non-muscle
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 18
    Exon count:
    44
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 18 NC_052549.1 (2345560..2438788, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 18 NC_052590.1 (1915014..2008104, complement)

    Chromosome 18 - NC_052549.1Genomic Context describing neighboring genes Neighboring gene ring finger protein 222 Neighboring gene nudE neurodevelopment protein 1 like 1 Neighboring gene uncharacterized LOC101749287 Neighboring gene uncharacterized LOC107054732 Neighboring gene coiled-coil domain containing 42

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Developmental relationship of myosin binding proteins (myomesin, connectin and C-protein) to myosin in chicken somites as studied by immunofluorescence microscopy. Yang YG, et al. Cell Struct Funct, 2000 Jun. PMID 10984101
    2. Evidence for inserted sequences in the head region of nonmuscle myosin specific to the nervous system. Cloning of the cDNA encoding the myosin heavy chain-B isoform of vertebrate nonmuscle myosin. Takahashi M, et al. J Biol Chem, 1992 Sep 5. PMID 1355479
    3. Two distinct nonmuscle myosin-heavy-chain mRNAs are differentially expressed in various chicken tissues. Identification of a novel gene family of vertebrate non-sarcomeric myosin heavy chains. Katsuragawa Y, et al. Eur J Biochem, 1989 Oct 1. PMID 2806244

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cytoskeletal motor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of myosin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    myosin-10
    Names
    heavy polypeptide 10
    myosin, heavy polypeptide 10, non-muscle
    nonmuscle myosin II heavy chain-B
    nonmuscle myosin heavy chain

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_205474.2 → NP_990805.1  myosin-10

      See identical proteins and their annotated locations for NP_990805.1

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000315
      UniProtKB/TrEMBL
      A0A8V1AJQ0, Q789A4
      Related
      ENSGALP00010043669.1, ENSGALT00010070978.1
      Conserved Domains (10) summary
      cd14920
      Location:99 → 802
      MYSc_Myh10; class II myosin heavy chain 10, motor domain
      pfam00063
      Location:87 → 802
      Myosin_head; Myosin head (motor domain)
      pfam01576
      Location:879 → 1959
      Myosin_tail_1; Myosin tail
      pfam02736
      Location:34 → 72
      Myosin_N; Myosin N-terminal SH3-like domain
      cd16269
      Location:1624 → 1635
      GBP_C; coiled coil [structural motif]
      cl19219
      Location:1075 → 1164
      DUF342; Protein of unknown function (DUF342)
      cl19511
      Location:1142 → 1253
      DUF2317; Uncharacterized protein conserved in bacteria (DUF2317)
      cl19818
      Location:1676 → 1727
      DUF106; Integral membrane protein DUF106
      cl20817
      Location:1535 → 1644
      GBP_C; Guanylate-binding protein, C-terminal domain
      cl24005
      Location:1804 → 1898
      DUF2570; Protein of unknown function (DUF2570)

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052549.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      2345560..2438788 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040649469.2 → XP_040505403.1  myosin-10 isoform X4

      UniProtKB/TrEMBL
      A0A8V1AHP5, F1NGG0, Q789A6
      Conserved Domains (3) summary
      cd14920
      Location:99 → 771
      MYSc_Myh10; class II myosin heavy chain 10, motor domain
      pfam01576
      Location:848 → 1928
      Myosin_tail_1; Myosin tail
      pfam02736
      Location:33 → 68
      Myosin_N; Myosin N-terminal SH3-like domain

    2. XM_015295125.4 → XP_015150611.1  myosin-10 isoform X2

      UniProtKB/TrEMBL
      A0A8V1ANB1, Q02015
      Related
      ENSGALP00010043670.1, ENSGALT00010070979.1
      Conserved Domains (3) summary
      cd14920
      Location:99 → 792
      MYSc_Myh10; class II myosin heavy chain 10, motor domain
      pfam01576
      Location:869 → 1949
      Myosin_tail_1; Myosin tail
      pfam02736
      Location:33 → 68
      Myosin_N; Myosin N-terminal SH3-like domain

    3. XM_046901984.1 → XP_046757940.1  myosin-10 isoform X3

      UniProtKB/TrEMBL
      Q789A5
      Related
      ENSGALP00010043671.1, ENSGALT00010070980.1

    4. XM_015295124.3 → XP_015150610.1  myosin-10 isoform X1

      UniProtKB/TrEMBL
      A0A8V1AJQ0, Q789A4
      Conserved Domains (10) summary
      cd14920
      Location:99 → 802
      MYSc_Myh10; class II myosin heavy chain 10, motor domain
      pfam00063
      Location:87 → 802
      Myosin_head; Myosin head (motor domain)
      pfam01576
      Location:879 → 1959
      Myosin_tail_1; Myosin tail
      pfam02736
      Location:34 → 72
      Myosin_N; Myosin N-terminal SH3-like domain
      cd16269
      Location:1624 → 1635
      GBP_C; coiled coil [structural motif]
      cl19219
      Location:1075 → 1164
      DUF342; Protein of unknown function (DUF342)
      cl19511
      Location:1142 → 1253
      DUF2317; Uncharacterized protein conserved in bacteria (DUF2317)
      cl19818
      Location:1676 → 1727
      DUF106; Integral membrane protein DUF106
      cl20817
      Location:1535 → 1644
      GBP_C; Guanylate-binding protein, C-terminal domain
      cl24005
      Location:1804 → 1898
      DUF2570; Protein of unknown function (DUF2570)

    5. XM_040649470.2 → XP_040505404.1  myosin-10 isoform X5

      UniProtKB/TrEMBL
      A0A8V1ANB1
      Conserved Domains (4) summary
      COG1196
      Location:829 → 1669
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      COG5022
      Location:1 → 1159
      COG5022; Myosin heavy chain [General function prediction only]
      cl30717
      Location:1600 → 1766
      InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
      cl22853
      Location:2 → 582
      Motor_domain; Myosin and Kinesin motor domain

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052590.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      1915014..2008104 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046929274.1 → XP_046785230.1  myosin-10 isoform X4

      UniProtKB/TrEMBL
      F1NGG0, Q789A6

    2. XM_046929271.1 → XP_046785227.1  myosin-10 isoform X2

      UniProtKB/TrEMBL
      Q02015

    3. XM_046929272.1 → XP_046785228.1  myosin-10 isoform X3

      UniProtKB/TrEMBL
      Q789A5

    4. XM_046929270.1 → XP_046785226.1  myosin-10 isoform X1

      UniProtKB/TrEMBL
      Q789A4

    5. XM_046929275.1 → XP_046785231.1  myosin-10 isoform X5

    Nucleotide Protein
    Heading Accession and Version

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