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    rad50 DNA double-strand break repair ATPase Rad50 [ Archaeoglobus profundus DSM 5631 ]

    Gene ID: 8738706, updated on 3-May-2023

    Summary

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    Gene symbol
    rad50
    Gene description
    DNA double-strand break repair ATPase Rad50
    Locus tag
    ARCPR_RS00295
    Gene type
    protein coding
    Organism
    Archaeoglobus profundus DSM 5631 (strain: DSM 5631, type-material: type strain of Archaeoglobus profundus)
    Lineage
    Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae; Archaeoglobus
    Old locus tag
    Arcpr_0060
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    Genomic context

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    Sequence:
    NC_013741.1 (49262..51868)

    NC_013741.1Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene TATA-box-binding protein Neighboring gene exonuclease SbcCD subunit D Neighboring gene DNA double-strand break repair nuclease NurA Neighboring gene hypothetical protein Neighboring gene tyrosine--tRNA ligase Neighboring gene translation initiation factor eIF-1A

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_013741.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mre11 and Rad50 from Pyrococcus furiosus: cloning and biochemical characterization reveal an evolutionarily conserved multiprotein machine. Hopfner KP, et al. J Bacteriol, 2000 Nov. PMID 11029422, Free PMC Article
    2. Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase. Hopfner KP, et al. Cell, 2001 May 18. PMID 11371344
    3. Complete genome sequence of Archaeoglobus profundus type strain (AV18). von Jan M, et al. Stand Genomic Sci, 2010 Jun 15. PMID 21304717, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    General protein information

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    Preferred Names
    DNA double-strand break repair ATPase Rad50

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_013741.1 Reference assembly

      Range
      49262..51868
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_012939472.1 DNA double-strand break repair ATPase Rad50 [Archaeoglobus profundus]

      See identical proteins and their annotated locations for WP_012939472.1

      UniProtKB/TrEMBL
      D2RFR1
      Conserved Domains (6) summary
      cd03240
      Location:770 → 855
      ABC_Rad50; ATP-binding cassette domain of Rad50
      PRK03918
      Location:1 → 868
      PRK03918; chromosome segregation protein; Provisional
      pfam04423
      Location:415 → 463
      Rad50_zn_hook; Rad50 zinc hook motif
      pfam07851
      Location:269 → 377
      TMPIT; TMPIT-like protein
      cl09111
      Location:601 → 692
      Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
      cl21455
      Location:3 → 140
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    Nucleotide Protein
    Heading Accession and Version

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