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    ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 [ Camelus ferus (Wild Bactrian camel) ]

    Gene ID: 102519349, updated on 10-Mar-2024

    Summary

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    Gene symbol
    ARAP2
    Gene description
    ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
    Locus tag
    CB1_001456001
    See related
    EnsemblRapid:ENSCFEG00005007775
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Camelus ferus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus
    Orthologs
    human mouse all
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    Genomic context

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    See ARAP2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    33
    Annotation release Status Assembly Chr Location
    102 current BCGSAC_Cfer_1.0 (GCF_009834535.1) 2 NC_045697.1 (25911459..26073707, complement)
    101 previous assembly CB1 (GCF_000311805.1) Unplaced Scaffold NW_006211631.1 (1234208..1397052, complement)

    Chromosome 2 - NC_045697.1Genomic Context describing neighboring genes Neighboring gene elongation factor 1-alpha 1-like Neighboring gene elongation factor 1-alpha 1-like Neighboring gene death domain containing 1 Neighboring gene uncharacterized LOC116667126

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol-3,4,5-trisphosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Camelus ferus Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference BCGSAC_Cfer_1.0 Primary Assembly

    Genomic

    1. NC_045697.1 Reference BCGSAC_Cfer_1.0 Primary Assembly

      Range
      25911459..26073707 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_032495553.1 → XP_032351444.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8B8UA35
      Related
      ENSCFEP00005013002.1, ENSCFET00005014521.1
      Conserved Domains (9) summary
      cd09490
      Location:6 → 68
      SAM_Arap1,2,3; SAM domain of Arap1,2,3 (angiotensin receptor-associated protein)
      cd04385
      Location:1109 → 1288
      RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
      cd13253
      Location:481 → 573
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:584 → 672
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13256
      Location:889 → 999
      PH3_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 3
      cd13259
      Location:1405 → 1515
      PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
      cd17227
      Location:1297 → 1394
      RA_ARAP2; Ras-associating (RA) domain found in Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 (ARAP2)
      cd08856
      Location:677 → 797
      ArfGap_ARAP2; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing protein 2
      cl17171
      Location:1012 → 1105
      PH-like; Pleckstrin homology-like domain

    2. XM_032495548.1 → XP_032351439.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8B8UA30
      Related
      ENSCFEP00005012926.1, ENSCFET00005014437.1
      Conserved Domains (9) summary
      cd09490
      Location:6 → 68
      SAM_Arap1,2,3; SAM domain of Arap1,2,3 (angiotensin receptor-associated protein)
      cd04385
      Location:1109 → 1288
      RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
      cd13253
      Location:481 → 573
      PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
      cd13254
      Location:584 → 672
      PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
      cd13256
      Location:889 → 999
      PH3_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 3
      cd13259
      Location:1428 → 1538
      PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
      cd17227
      Location:1320 → 1417
      RA_ARAP2; Ras-associating (RA) domain found in Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 (ARAP2)
      cd08856
      Location:677 → 797
      ArfGap_ARAP2; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing protein 2
      cl17171
      Location:1012 → 1105
      PH-like; Pleckstrin homology-like domain
    Nucleotide Protein
    Heading Accession and Version

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