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    zeb1 zinc finger E-box binding homeobox 1 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 548525, updated on 5-Mar-2024

    Summary

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    Official Symbol
    zeb1provided by Xenbase
    Official Full Name
    zinc finger E-box binding homeobox 1provided by Xenbase
    Primary source
    Xenbase:XB-GENE-484655
    See related
    Ensembl:ENSXETG00000011655
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    bzp; zeb; tcf8; areb6; fecd6; nil2a; zfhep; zfhx1; nil-2a; zfhx1a; nil-2-a; deltaef1
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 6
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 6 NC_030682.2 (23150775..23213344, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 6 NC_030682.1 (14906463..14967919, complement)

    Chromosome 6 - NC_030682.2Genomic Context describing neighboring genes Neighboring gene kinesin family member 5B Neighboring gene Rho GTPase activating protein 12 Neighboring gene zinc finger protein 438 Neighboring gene supervillin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC97552

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger E-box-binding homeobox 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001015808.1 → NP_001015808.1  zinc finger E-box-binding homeobox 1

      See identical proteins and their annotated locations for NP_001015808.1

      Status: PROVISIONAL

      Source sequence(s)
      BC090088
      UniProtKB/TrEMBL
      A0A6I8RPK4, Q5EB46
      Conserved Domains (6) summary
      smart00389
      Location:558 → 606
      HOX; Homeodomain
      COG5048
      Location:898 → 951
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:875 → 895
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:221 → 243
      zf-C2H2; Zinc finger, C2H2 type
      pfam08690
      Location:9 → 151
      GET2; GET complex subunit GET2
      pfam13465
      Location:915 → 940
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030682.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      23150775..23213344 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012964650.3 → XP_012820104.1  zinc finger E-box-binding homeobox 1 isoform X1

      UniProtKB/TrEMBL
      A0A6I8RPK4, A0A8J0SN60
      Conserved Domains (6) summary
      smart00355
      Location:203 → 225
      ZnF_C2H2; zinc finger
      smart00389
      Location:580 → 633
      HOX; Homeodomain
      sd00017
      Location:897 → 917
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:243 → 265
      zf-C2H2; Zinc finger, C2H2 type
      pfam08690
      Location:120 → 173
      GET2; GET complex subunit GET2
      pfam13465
      Location:937 → 962
      zf-H2C2_2; Zinc-finger double domain

    2. XM_031903368.1 → XP_031759228.1  zinc finger E-box-binding homeobox 1 isoform X3

      UniProtKB/TrEMBL
      A0A6I8RPK4, A0A8J0SG78
      Conserved Domains (4) summary
      sd00017
      Location:691 → 711
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:37 → 59
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:731 → 756
      zf-H2C2_2; Zinc-finger double domain
      cl00084
      Location:374 → 427
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.

    3. XM_031903367.1 → XP_031759227.1  zinc finger E-box-binding homeobox 1 isoform X2

      UniProtKB/TrEMBL
      A0A6I8RPK4, F7ES16
      Related
      ENSXETP00000025489.5, ENSXETT00000025489.5
      Conserved Domains (6) summary
      smart00355
      Location:189 → 211
      ZnF_C2H2; zinc finger
      sd00017
      Location:883 → 903
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:229 → 251
      zf-C2H2; Zinc finger, C2H2 type
      pfam08690
      Location:47 → 159
      GET2; GET complex subunit GET2
      pfam13465
      Location:923 → 948
      zf-H2C2_2; Zinc-finger double domain
      cl00084
      Location:566 → 619
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.

    4. XM_012964653.3 → XP_012820107.1  zinc finger E-box-binding homeobox 1 isoform X3

      UniProtKB/TrEMBL
      A0A6I8RPK4, A0A8J0SG78
      Conserved Domains (4) summary
      sd00017
      Location:691 → 711
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:37 → 59
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:731 → 756
      zf-H2C2_2; Zinc-finger double domain
      cl00084
      Location:374 → 427
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    Nucleotide Protein Strain
    Heading Accession and Version

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