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    Smr2 submaxillary gland androgen regulated protein 2 [ Mus musculus (house mouse) ]

    Gene ID: 20600, updated on 23-Jun-2021

    Summary

    Official Symbol
    Smr2provided by MGI
    Official Full Name
    submaxillary gland androgen regulated protein 2provided by MGI
    Primary source
    MGI:MGI:102762
    See related
    Ensembl:ENSMUSG00000029281
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    MSG; MSG2; Vcs2
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

    See Smr2 in Genome Data Viewer
    Location:
    5; 5 E1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (88234415..88256912)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (88086556..88109053)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (88515581..88538078)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene submaxillary gland androgen regulated protein 3A Neighboring gene heat shock protein 5 pseudogene Neighboring gene predicted gene 42622 Neighboring gene heat shock protein 8 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Clone Names

    • MGC130573

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables endopeptidase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables endopeptidase inhibitor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables peptidase inhibitor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in cellular response to lipopolysaccharide ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of peptidase activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of sensory perception of pain IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in regulation of sensory perception of pain ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within response to toxic substance IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in extracellular region ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    submaxillary gland androgen regulated protein 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001252679.1NP_001239608.1  submaxillary gland androgen regulated protein 2 isoform 2 precursor

      See identical proteins and their annotated locations for NP_001239608.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains two alternate internal exons and initiates translation at an alternate start codon, compared to variant 1. Variants 2, 3 and 4 encode the same isoform (2) which has a distinct N-terminus, compared to isoform 1.
      Source sequence(s)
      AC154123, AC163331
      Consensus CDS
      CCDS80321.1
      UniProtKB/Swiss-Prot
      O35979
      Related
      ENSMUSP00000143443.2, ENSMUST00000196070.2
      Conserved Domains (1) summary
      pfam15621
      Location:1111
      PROL5-SMR; Proline-rich submaxillary gland androgen-regulated family
    2. NM_001252680.1NP_001239609.1  submaxillary gland androgen regulated protein 2 isoform 2 precursor

      See identical proteins and their annotated locations for NP_001239609.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) contains an alternate internal exon and initiates translation at an alternate start codon, compared to variant 1. Variants 2, 3 and 4 encode the same isoform (2) which has a distinct N-terminus, compared to isoform 1.
      Source sequence(s)
      AC154123, AC163331
      Consensus CDS
      CCDS80321.1
      UniProtKB/Swiss-Prot
      O35979
      Conserved Domains (1) summary
      pfam15621
      Location:1111
      PROL5-SMR; Proline-rich submaxillary gland androgen-regulated family
    3. NM_001252681.1NP_001239610.1  submaxillary gland androgen regulated protein 2 isoform 2 precursor

      See identical proteins and their annotated locations for NP_001239610.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks an internal exon, contains an alternate internal exon and initiates translation at an alternate start codon, compared to variant 1. Variants 2, 3 and 4 encode the same isoform (2) which has a distinct N-terminus, compared to isoform 1.
      Source sequence(s)
      AC154123, AC163331
      Consensus CDS
      CCDS80321.1
      UniProtKB/Swiss-Prot
      O35979
      Related
      ENSMUSP00000142688.2, ENSMUST00000196477.5
      Conserved Domains (1) summary
      pfam15621
      Location:1111
      PROL5-SMR; Proline-rich submaxillary gland androgen-regulated family
    4. NM_021289.2NP_067264.2  submaxillary gland androgen regulated protein 2 isoform 1 precursor

      See identical proteins and their annotated locations for NP_067264.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes isoform (1).
      Source sequence(s)
      AC154123, AC163331
      Consensus CDS
      CCDS39137.1
      UniProtKB/Swiss-Prot
      O35985
      Related
      ENSMUSP00000084271.4, ENSMUST00000087043.8
      Conserved Domains (1) summary
      pfam15621
      Location:1111
      PROL5-SMR; Proline-rich submaxillary gland androgen-regulated family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      88234415..88256912
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030254268.1XP_030110128.1  submaxillary gland androgen regulated protein 2 isoform X1

      Related
      ENSMUSP00000142444.2, ENSMUST00000199635.5
      Conserved Domains (1) summary
      pfam15621
      Location:1116
      PROL5-SMR; Proline-rich submaxillary gland androgen-regulated family
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