fgl2a fibrinogen-like 2a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: fgl2aprovided by ZNC
Official Full Name: fibrinogen-like 2aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-9506
See related: Ensembl:ENSDARG00000019861 AllianceGenome:ZFIN:ZDB-GENE-030131-9506
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fgl2; wu:fj83c10; zgc:136619; si:ch211-276e22.3
Summary: Predicted to enable signaling receptor binding activity. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Orthologous to human FGL2 (fibrinogen like 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	4	NC_007115.7 (20178694..20181964, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	4	NC_007115.6 (20457719..20460989, complement)

Chromosome 4 - NC_007115.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Component	Evidence Code	Pubs
is_active_in collagen-containing extracellular matrix	IBA Inferred from Biological aspect of Ancestor more info
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: fibrinogen-like 2a

Names: fibrinogen-like 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001025539.2 → NP_001020710.1 fibrinogen-like 2a precursor

See identical proteins and their annotated locations for NP_001020710.1

Status: PROVISIONAL

Source sequence(s)

BX855588

UniProtKB/TrEMBL

Q1ECY1, Q5TYU3

Related

ENSDARP00000023829.6, ENSDART00000022539.8

Conserved Domains (1) summary

cd00087
Location:219 → 447

FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...