POK Vps52 / Sac2 family [Arabidopsis thaliana (thale cress)] - Gene

Summary

Gene symbol: POK
Gene description: Vps52 / Sac2 family
Primary source: Araport:AT1G71270
Locus tag: AT1G71270
See related: TAIR:AT1G71270
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ARABIDOPSIS THALIANA VPS52 HOMOLOG; ATVPS52; F3I17.8; F3I17_8; POKY POLLEN TUBE; T-DNA TRANSMISSION DEFECT 8; TTD8; VPS52
Summary: Encodes a homolog of the yeast Vps52p/SAC2. Involved in pollen tube germination and growth. Located in multiple endomembrane organelles including the golgi. The yeast protein has been shown to be located at the late Golgi and to function in a complex involved in retrograde trafficking of vesicles between the early endosomal compartment and the trans-Golgi network.
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Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

Data indicatethat POK/AtVPS52 (VPS52) is an important virulence target.
Title: An Aphid Effector Targets Trafficking Protein VPS52 in a Host-Specific Manner to Promote Virulence.
associates with Golgi and post-Golgi compartments
Title: The POK/AtVPS52 protein localizes to several distinct post-Golgi compartments in sporophytic and gametophytic cells.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_105796.3

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within pollen tube growth	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within sexual reproduction	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of GARP complex	IDA Inferred from Direct Assay more info	PubMed
located_in Golgi apparatus	IDA Inferred from Direct Assay more info	PubMed
located_in Golgi apparatus	ISM Inferred from Sequence Model more info
located_in Golgi membrane	IDA Inferred from Direct Assay more info	PubMed
located_in endomembrane system	IDA Inferred from Direct Assay more info	PubMed

NP_565015.1

POKY POLLEN TUBE (POK); CONTAINS InterPro DOMAIN/s: Vps52/Sac2 (InterPro:IPR007258); BEST Arabidopsis thaliana protein match is: Vps52 / Sac2 family (TAIR:AT1G71300.1); Has 820 Blast hits to 773 proteins in 240 species: Archae - 10; Bacteria - 70; Metazoa - 261; Fungi - 156; Plants - 82; Viruses - 2; Other Eukaryotes - 239 (source: NCBI BLink).