U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    PABIR1 PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1 [ Homo sapiens (human) ]

    Gene ID: 116224, updated on 13-May-2022

    Summary

    Official Symbol
    PABIR1provided by HGNC
    Official Full Name
    PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1provided by HGNC
    Primary source
    HGNC:HGNC:23490
    See related
    Ensembl:ENSG00000187866 MIM:617249; AllianceGenome:HGNC:23490
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    C9orf42; FAM122A
    Summary
    Enables protein serine/threonine phosphatase inhibitor activity. Involved in mitotic G2/M transition checkpoint; positive regulation of cell growth; and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See PABIR1 in Genome Data Viewer
    Location:
    9q21.11
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    110 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (68780065..68785566)
    110 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (80953589..80959090)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (71394981..71400482)

    Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene TMEM252 divergent transcript Neighboring gene uncharacterized LOC105376071 Neighboring gene dermatan sulfate epimerase pseudogene Neighboring gene phosphatidylinositol-4-phosphate 5-kinase type 1 beta Neighboring gene adaptor related protein complex 3 subunit mu 2 pseudogene Neighboring gene RNA, U6 small nuclear 820, pseudogene

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC17347

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein serine/threonine phosphatase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein serine/threonine phosphatase inhibitor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    PPP2R1A-PPP2R2A-interacting phosphatase regulator 1
    Names
    PABIR family member 1
    family with sequence similarity 122A
    protein FAM122A

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_138333.5NP_612206.5  PPP2R1A-PPP2R2A-interacting phosphatase regulator 1

      Status: VALIDATED

      Source sequence(s)
      AL354794, BC013062, BX110658
      Consensus CDS
      CCDS6623.2
      Related
      ENSP00000377807.5, ENST00000394264.7

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

      Range
      68780065..68785566
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060933.1 Alternate T2T-CHM13v2.0

      Range
      80953589..80959090
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)