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    MYH10 myosin heavy chain 10 [ Bos taurus (cattle) ]

    Gene ID: 317655, updated on 3-Apr-2024

    Summary

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    Official Symbol
    MYH10provided by VGNC
    Official Full Name
    myosin heavy chain 10provided by VGNC
    Primary source
    VGNC:VGNC:31794
    See related
    BGD:BT23905; Ensembl:ENSBTAG00000021151
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 19
    Exon count:
    45
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (28061573..28183702, complement)

    Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene basic proline-rich protein-like Neighboring gene ubiquitin-conjugating enzyme E2 B-like Neighboring gene nudE neurodevelopment protein 1 like 1 Neighboring gene ring finger protein 222 Neighboring gene uncharacterized LOC132343043 Neighboring gene small nucleolar RNA SNORA79 Neighboring gene U6 spliceosomal RNA Neighboring gene coiled-coil domain containing 42

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Neuronal cell expression of inserted isoforms of vertebrate nonmuscle myosin heavy chain II-B. Itoh K, et al. J Biol Chem, 1995 Jun 16. PMID 7782316
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cytoskeletal motor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of myosin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    myosin-10
    Names
    NMMHC II-b
    NMMHC-B
    NMMHC-IIB
    cellular myosin heavy chain, type B
    myosin heavy chain, non-muscle IIb
    myosin, heavy polypeptide 10, non-muscle
    non-muscle myosin heavy chain B
    non-muscle myosin heavy chain IIb
    nonmuscle myosin heavy chain B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174834.1 → NP_777259.1  myosin-10

      See identical proteins and their annotated locations for NP_777259.1

      Status: PROVISIONAL

      Source sequence(s)
      AB022023
      UniProtKB/Swiss-Prot
      Q27991
      UniProtKB/TrEMBL
      A0A452DIZ9
      Related
      ENSBTAP00000090309.1, ENSBTAT00000098818.1
      Conserved Domains (8) summary
      cd14920
      Location:99 → 771
      MYSc_Myh10; class II myosin heavy chain 10, motor domain
      pfam00063
      Location:87 → 771
      Myosin_head; Myosin head (motor domain)
      pfam01576
      Location:848 → 1928
      Myosin_tail_1; Myosin tail
      pfam02736
      Location:34 → 72
      Myosin_N; Myosin N-terminal SH3-like domain
      pfam11853
      Location:1062 → 1093
      DUF3373; Protein of unknown function (DUF3373)
      cl19511
      Location:1111 → 1222
      DUF2317; Uncharacterized protein conserved in bacteria (DUF2317)
      cl19818
      Location:1645 → 1696
      DUF106; Integral membrane protein DUF106
      cl24005
      Location:1769 → 1867
      DUF2570; Protein of unknown function (DUF2570)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      28061573..28183702 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059877752.1 → XP_059733735.1  myosin-10 isoform X1

    2. XM_005220298.5 → XP_005220355.1  myosin-10 isoform X1

      See identical proteins and their annotated locations for XP_005220355.1

      UniProtKB/TrEMBL
      A0A452DIZ9
      Conserved Domains (8) summary
      cd14920
      Location:99 → 802
      MYSc_Myh10; class II myosin heavy chain 10, motor domain
      pfam00063
      Location:87 → 802
      Myosin_head; Myosin head (motor domain)
      pfam01576
      Location:879 → 1959
      Myosin_tail_1; Myosin tail
      pfam02736
      Location:34 → 72
      Myosin_N; Myosin N-terminal SH3-like domain
      pfam11853
      Location:1093 → 1124
      DUF3373; Protein of unknown function (DUF3373)
      cl19511
      Location:1142 → 1253
      DUF2317; Uncharacterized protein conserved in bacteria (DUF2317)
      cl19818
      Location:1676 → 1727
      DUF106; Integral membrane protein DUF106
      cl24005
      Location:1800 → 1898
      DUF2570; Protein of unknown function (DUF2570)

    3. XM_005220299.5 → XP_005220356.1  myosin-10 isoform X2

      UniProtKB/TrEMBL
      A0A452DIZ9
      Conserved Domains (8) summary
      cd14920
      Location:99 → 792
      MYSc_Myh10; class II myosin heavy chain 10, motor domain
      pfam00063
      Location:87 → 792
      Myosin_head; Myosin head (motor domain)
      pfam01576
      Location:869 → 1949
      Myosin_tail_1; Myosin tail
      pfam02736
      Location:34 → 72
      Myosin_N; Myosin N-terminal SH3-like domain
      pfam11853
      Location:1083 → 1114
      DUF3373; Protein of unknown function (DUF3373)
      cl19511
      Location:1132 → 1243
      DUF2317; Uncharacterized protein conserved in bacteria (DUF2317)
      cl19818
      Location:1666 → 1717
      DUF106; Integral membrane protein DUF106
      cl24005
      Location:1790 → 1888
      DUF2570; Protein of unknown function (DUF2570)

    4. XM_059877753.1 → XP_059733736.1  myosin-10 isoform X3

      Related
      ENSBTAP00000065840.2, ENSBTAT00000075528.2

    5. XM_005220297.5 → XP_005220354.1  myosin-10 isoform X1

      See identical proteins and their annotated locations for XP_005220354.1

      UniProtKB/TrEMBL
      A0A452DIZ9
      Related
      ENSBTAP00000075953.1, ENSBTAT00000132144.1
      Conserved Domains (8) summary
      cd14920
      Location:99 → 802
      MYSc_Myh10; class II myosin heavy chain 10, motor domain
      pfam00063
      Location:87 → 802
      Myosin_head; Myosin head (motor domain)
      pfam01576
      Location:879 → 1959
      Myosin_tail_1; Myosin tail
      pfam02736
      Location:34 → 72
      Myosin_N; Myosin N-terminal SH3-like domain
      pfam11853
      Location:1093 → 1124
      DUF3373; Protein of unknown function (DUF3373)
      cl19511
      Location:1142 → 1253
      DUF2317; Uncharacterized protein conserved in bacteria (DUF2317)
      cl19818
      Location:1676 → 1727
      DUF106; Integral membrane protein DUF106
      cl24005
      Location:1800 → 1898
      DUF2570; Protein of unknown function (DUF2570)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q27991.2 GenPept UniProtKB/Swiss-Prot:Q27991

    Gene LinkOut

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