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    MYH10 myosin heavy chain 10 [ Bos taurus (cattle) ]

    Gene ID: 317655, updated on 22-May-2022

    Summary

    Official Symbol
    MYH10provided by VGNC
    Official Full Name
    myosin heavy chain 10provided by VGNC
    Primary source
    VGNC:VGNC:31794
    See related
    BGD:BT23905; Ensembl:ENSBTAG00000021151
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
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    Genomic context

    See MYH10 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    43
    Annotation release Status Assembly Chr Location
    106 current ARS-UCD1.2 (GCF_002263795.1) 19 NC_037346.1 (28061491..28183071, complement)
    105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 19 AC_000176.1 (28679649..28801223, complement)

    Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene ubiquitin-conjugating enzyme E2 B pseudogene Neighboring gene nudE neurodevelopment protein 1 like 1 Neighboring gene ring finger protein 222 Neighboring gene small nucleolar RNA SNORA79 Neighboring gene U6 spliceosomal RNA Neighboring gene coiled-coil domain containing 42

    Genomic regions, transcripts, and products

    Pathways from PubChem

    General gene information

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables ADP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA stem-loop binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables mRNA 5'-UTR binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in actin filament-based movement IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of protein secretion IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cell cortex IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cleavage furrow IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in lamellipodium IEA
    Inferred from Electronic Annotation
    more info
     
    located_in midbody IEA
    Inferred from Electronic Annotation
    more info
     
    located_in myosin II filament IEA
    Inferred from Electronic Annotation
    more info
     
    part_of polysome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in stress fiber IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    myosin-10
    Names
    NMMHC II-b
    NMMHC-B
    NMMHC-IIB
    cellular myosin heavy chain, type B
    myosin heavy chain, non-muscle IIb
    myosin, heavy polypeptide 10, non-muscle
    non-muscle myosin heavy chain B
    non-muscle myosin heavy chain IIb
    nonmuscle myosin heavy chain B

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174834.1NP_777259.1  myosin-10

      See identical proteins and their annotated locations for NP_777259.1

      Status: PROVISIONAL

      Source sequence(s)
      AB022023
      UniProtKB/Swiss-Prot
      Q27991
      Related
      ENSBTAP00000065840.1, ENSBTAT00000075528.1
      Conserved Domains (8) summary
      cd14920
      Location:99771
      MYSc_Myh10; class II myosin heavy chain 10, motor domain
      pfam00063
      Location:87771
      Myosin_head; Myosin head (motor domain)
      pfam01576
      Location:8481928
      Myosin_tail_1; Myosin tail
      pfam02736
      Location:3472
      Myosin_N; Myosin N-terminal SH3-like domain
      pfam11853
      Location:10621093
      DUF3373; Protein of unknown function (DUF3373)
      cl19511
      Location:11111222
      DUF2317; Uncharacterized protein conserved in bacteria (DUF2317)
      cl19818
      Location:16451696
      DUF106; Integral membrane protein DUF106
      cl24005
      Location:17691867
      DUF2570; Protein of unknown function (DUF2570)

    RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD1.2 Primary Assembly

    Genomic

    1. NC_037346.1 Reference ARS-UCD1.2 Primary Assembly

      Range
      28061491..28183071 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005220299.4XP_005220356.1  myosin-10 isoform X2

      Conserved Domains (8) summary
      cd14920
      Location:99792
      MYSc_Myh10; class II myosin heavy chain 10, motor domain
      pfam00063
      Location:87792
      Myosin_head; Myosin head (motor domain)
      pfam01576
      Location:8691949
      Myosin_tail_1; Myosin tail
      pfam02736
      Location:3472
      Myosin_N; Myosin N-terminal SH3-like domain
      pfam11853
      Location:10831114
      DUF3373; Protein of unknown function (DUF3373)
      cl19511
      Location:11321243
      DUF2317; Uncharacterized protein conserved in bacteria (DUF2317)
      cl19818
      Location:16661717
      DUF106; Integral membrane protein DUF106
      cl24005
      Location:17901888
      DUF2570; Protein of unknown function (DUF2570)
    2. XM_005220297.4XP_005220354.1  myosin-10 isoform X1

      See identical proteins and their annotated locations for XP_005220354.1

      Conserved Domains (8) summary
      cd14920
      Location:99802
      MYSc_Myh10; class II myosin heavy chain 10, motor domain
      pfam00063
      Location:87802
      Myosin_head; Myosin head (motor domain)
      pfam01576
      Location:8791959
      Myosin_tail_1; Myosin tail
      pfam02736
      Location:3472
      Myosin_N; Myosin N-terminal SH3-like domain
      pfam11853
      Location:10931124
      DUF3373; Protein of unknown function (DUF3373)
      cl19511
      Location:11421253
      DUF2317; Uncharacterized protein conserved in bacteria (DUF2317)
      cl19818
      Location:16761727
      DUF106; Integral membrane protein DUF106
      cl24005
      Location:18001898
      DUF2570; Protein of unknown function (DUF2570)
    3. XM_015458671.2XP_015314157.1  myosin-10 isoform X3

      Conserved Domains (8) summary
      cd14920
      Location:99781
      MYSc_Myh10; class II myosin heavy chain 10, motor domain
      pfam00063
      Location:87781
      Myosin_head; Myosin head (motor domain)
      pfam01576
      Location:8581938
      Myosin_tail_1; Myosin tail
      pfam02736
      Location:3472
      Myosin_N; Myosin N-terminal SH3-like domain
      pfam11853
      Location:10721103
      DUF3373; Protein of unknown function (DUF3373)
      cl19511
      Location:11211232
      DUF2317; Uncharacterized protein conserved in bacteria (DUF2317)
      cl19818
      Location:16551706
      DUF106; Integral membrane protein DUF106
      cl24005
      Location:17791877
      DUF2570; Protein of unknown function (DUF2570)
    4. XM_005220298.4XP_005220355.1  myosin-10 isoform X1

      See identical proteins and their annotated locations for XP_005220355.1

      Conserved Domains (8) summary
      cd14920
      Location:99802
      MYSc_Myh10; class II myosin heavy chain 10, motor domain
      pfam00063
      Location:87802
      Myosin_head; Myosin head (motor domain)
      pfam01576
      Location:8791959
      Myosin_tail_1; Myosin tail
      pfam02736
      Location:3472
      Myosin_N; Myosin N-terminal SH3-like domain
      pfam11853
      Location:10931124
      DUF3373; Protein of unknown function (DUF3373)
      cl19511
      Location:11421253
      DUF2317; Uncharacterized protein conserved in bacteria (DUF2317)
      cl19818
      Location:16761727
      DUF106; Integral membrane protein DUF106
      cl24005
      Location:18001898
      DUF2570; Protein of unknown function (DUF2570)