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    TROAP trophinin associated protein [ Homo sapiens (human) ]

    Gene ID: 10024, updated on 6-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    METTL3 regulatory TROAP can regulate the progression of non-small cell lung cancer through PI3K/AKT and EMT signaling pathway.

    METTL3 regulatory TROAP can regulate the progression of non-small cell lung cancer through PI3K/AKT and EMT signaling pathway.
    Xu M, Yu J, Liu X, Jia W, Duan Y, Ma D, Ma J, Lei W, Tai W.

    08/30/2023
    TROAP Promotes the Proliferation, Migration, and Metastasis of Kidney Renal Clear Cell Carcinoma with the Help of STAT3.

    TROAP Promotes the Proliferation, Migration, and Metastasis of Kidney Renal Clear Cell Carcinoma with the Help of STAT3.
    Wang J, Wan H, Mi Y, Wu S, Li J, Zhu L., Free PMC Article

    06/15/2023
    Tastin promotes non-small-cell lung cancer progression through the ErbB4, PI3K/AKT, and ERK1/2 pathways.

    Tastin promotes non-small-cell lung cancer progression through the ErbB4, PI3K/AKT, and ERK1/2 pathways.
    Yue A, Chen M, Dai S, Zhang Y, Wei W, Fan L, Wang F, Zhang F, Yu H, Lu Y, Lei Y., Free PMC Article

    06/14/2023
    MiR-532-3p suppresses cell viability, migration and invasion of clear cell renal cell carcinoma through targeting TROAP.

    MiR-532-3p suppresses cell viability, migration and invasion of clear cell renal cell carcinoma through targeting TROAP.
    Gao B, Wang L, Zhang Y, Zhang N, Han M, Liu H, Sun D, Liu Y., Free PMC Article

    03/12/2022
    TROAP switches DYRK1 activity to drive hepatocellular carcinoma progression.

    TROAP switches DYRK1 activity to drive hepatocellular carcinoma progression.
    Li L, Wei JR, Song Y, Fang S, Du Y, Li Z, Zeng TT, Zhu YH, Li Y, Guan XY., Free PMC Article

    10/9/2021
    Study found that TROAP expression correlates with patient survival and speculated that it may be involved in prostate cancer progression.

    TROAP regulates prostate cancer progression via the WNT3/survivin signalling pathways.
    Ye J, Chu C, Chen M, Shi Z, Gan S, Qu F, Pan X, Yang Q, Tian Y, Wang L, Yang W, Cui X.

    09/12/2020
    The present study suggests that TROAP plays an important role in promoting the proliferation, invasion, and metastasis of breast cancer.

    TROAP Promotes Breast Cancer Proliferation and Metastasis.
    Li K, Zhang R, Wei M, Zhao L, Wang Y, Feng X, Yang Y, Yang S, Zhang L., Free PMC Article

    12/7/2019
    Elevated TROAP expression is an independent predictor of poor survival in liver cancer.

    High Trophinin-Associated Protein Expression Is an Independent Predictor of Poor Survival in Liver Cancer.
    Jiao Y, Li Y, Lu Z, Liu Y.

    02/9/2019
    the present study provided evidence that TROAP serves a role in GC cells by promoting cell proliferation, cell cycle progression and invasion in vitro. Combined analysis of cell lines and datasets from a public database, demonstrated that TROAP overexpression may be used as a predictor of poor survival in patients with GC.

    Decreased expression of TROAP suppresses cellular proliferation, migration and invasion in gastric cancer.
    Jing K, Mao Q, Ma P.

    11/10/2018
    these results indicate that TROAP suppresses cellular growth and migration in hepatocellular carcinoma

    Downregulated Trophinin-Associated Protein Plays a Critical Role in Human Hepatocellular Carcinoma Through Upregulation of Tumor Cell Growth and Migration.
    Lian Y, Fan W, Huang Y, Wang H, Wang J, Zhou L, Wu X, Deng M, Huang Y., Free PMC Article

    10/6/2018
    the major function of tastin during mitosis is to maintain the structural and dynamic features of centrosomes, thereby contributing to spindle bipolarity.

    Tastin is required for bipolar spindle assembly and centrosome integrity during mitosis.
    Yang S, Liu X, Yin Y, Fukuda MN, Zhou J.

    01/21/2010
    plays an important role in mammalian cells by associating with the microtubular cytoskeleton

    Human tastin, a proline-rich cytoplasmic protein, associates with the microtubular cytoskeleton.
    Nadano D, Nakayama J, Matsuzawa S, Sato TA, Matsuda T, Fukuda MN., Free PMC Article

    01/21/2010
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