METTL3 regulatory TROAP can regulate the progression of non-small cell lung cancer through PI3K/AKT and EMT signaling pathway. | METTL3 regulatory TROAP can regulate the progression of non-small cell lung cancer through PI3K/AKT and EMT signaling pathway. Xu M, Yu J, Liu X, Jia W, Duan Y, Ma D, Ma J, Lei W, Tai W. | 08/30/2023 |
TROAP Promotes the Proliferation, Migration, and Metastasis of Kidney Renal Clear Cell Carcinoma with the Help of STAT3. | TROAP Promotes the Proliferation, Migration, and Metastasis of Kidney Renal Clear Cell Carcinoma with the Help of STAT3. Wang J, Wan H, Mi Y, Wu S, Li J, Zhu L., Free PMC Article | 06/15/2023 |
Tastin promotes non-small-cell lung cancer progression through the ErbB4, PI3K/AKT, and ERK1/2 pathways. | Tastin promotes non-small-cell lung cancer progression through the ErbB4, PI3K/AKT, and ERK1/2 pathways. Yue A, Chen M, Dai S, Zhang Y, Wei W, Fan L, Wang F, Zhang F, Yu H, Lu Y, Lei Y., Free PMC Article | 06/14/2023 |
MiR-532-3p suppresses cell viability, migration and invasion of clear cell renal cell carcinoma through targeting TROAP. | MiR-532-3p suppresses cell viability, migration and invasion of clear cell renal cell carcinoma through targeting TROAP. Gao B, Wang L, Zhang Y, Zhang N, Han M, Liu H, Sun D, Liu Y., Free PMC Article | 03/12/2022 |
TROAP switches DYRK1 activity to drive hepatocellular carcinoma progression. | TROAP switches DYRK1 activity to drive hepatocellular carcinoma progression. Li L, Wei JR, Song Y, Fang S, Du Y, Li Z, Zeng TT, Zhu YH, Li Y, Guan XY., Free PMC Article | 10/9/2021 |
Study found that TROAP expression correlates with patient survival and speculated that it may be involved in prostate cancer progression. | TROAP regulates prostate cancer progression via the WNT3/survivin signalling pathways. Ye J, Chu C, Chen M, Shi Z, Gan S, Qu F, Pan X, Yang Q, Tian Y, Wang L, Yang W, Cui X. | 09/12/2020 |
The present study suggests that TROAP plays an important role in promoting the proliferation, invasion, and metastasis of breast cancer. | TROAP Promotes Breast Cancer Proliferation and Metastasis. Li K, Zhang R, Wei M, Zhao L, Wang Y, Feng X, Yang Y, Yang S, Zhang L., Free PMC Article | 12/7/2019 |
Elevated TROAP expression is an independent predictor of poor survival in liver cancer. | High Trophinin-Associated Protein Expression Is an Independent Predictor of Poor Survival in Liver Cancer. Jiao Y, Li Y, Lu Z, Liu Y. | 02/9/2019 |
the present study provided evidence that TROAP serves a role in GC cells by promoting cell proliferation, cell cycle progression and invasion in vitro. Combined analysis of cell lines and datasets from a public database, demonstrated that TROAP overexpression may be used as a predictor of poor survival in patients with GC. | Decreased expression of TROAP suppresses cellular proliferation, migration and invasion in gastric cancer. Jing K, Mao Q, Ma P. | 11/10/2018 |
these results indicate that TROAP suppresses cellular growth and migration in hepatocellular carcinoma | Downregulated Trophinin-Associated Protein Plays a Critical Role in Human Hepatocellular Carcinoma Through Upregulation of Tumor Cell Growth and Migration. Lian Y, Fan W, Huang Y, Wang H, Wang J, Zhou L, Wu X, Deng M, Huang Y., Free PMC Article | 10/6/2018 |
the major function of tastin during mitosis is to maintain the structural and dynamic features of centrosomes, thereby contributing to spindle bipolarity. | Tastin is required for bipolar spindle assembly and centrosome integrity during mitosis. Yang S, Liu X, Yin Y, Fukuda MN, Zhou J. | 01/21/2010 |
plays an important role in mammalian cells by associating with the microtubular cytoskeleton | Human tastin, a proline-rich cytoplasmic protein, associates with the microtubular cytoskeleton. Nadano D, Nakayama J, Matsuzawa S, Sato TA, Matsuda T, Fukuda MN., Free PMC Article | 01/21/2010 |