| MiR-182 promotes apoptosis of neural cells in cerebral infarction rats by PI3K/AKT signaling pathway. | MiR-182 promotes apoptosis of neural cells in cerebral infarction rats by PI3K/AKT signaling pathway.
Yang R, Zeng C. | 01/5/2024 |
| Pentylenetetrazole-induced kindling rat model: miR-182 and miR-27b-3p mediated neuroprotective effect of thymoquinone in the hippocampus. | Pentylenetetrazole-induced kindling rat model: miR-182 and miR-27b-3p mediated neuroprotective effect of thymoquinone in the hippocampus.
Pala M, Meral I, Pala Acikgoz N, Gorucu Yilmaz Ş, Taslidere E, Okur SK, Acar S, Akbas F. | 07/30/2022 |
| Inhibition of miR-182-5p attenuates ROS and protects against myocardial ischemia-reperfusion injury by targeting STK17A. | Inhibition of miR-182-5p attenuates ROS and protects against myocardial ischemia-reperfusion injury by targeting STK17A.
Li X, Jin Y., Free PMC Article | 07/23/2022 |
| LncRNA PCAT19 Regulates Neuropathic Pain via Regulation of miR-182-5p/JMJD1A in a Rat Model of Chronic Constriction Injury. | LncRNA PCAT19 Regulates Neuropathic Pain via Regulation of miR-182-5p/JMJD1A in a Rat Model of Chronic Constriction Injury.
Huo M, Zheng X, Bai N, Xu R, Yang G, Zhao Z. | 04/23/2022 |
| MiR-182 Promotes Ischemia/Reperfusion-Induced Acute Kidney Injury in Rat by Targeting FoxO3. | MiR-182 Promotes Ischemia/Reperfusion-Induced Acute Kidney Injury in Rat by Targeting FoxO3.
Du Y, Ning JZ. | 11/27/2021 |
| HAGLR aggravates neuropathic pain and promotes inflammatory response and apoptosis of lipopolysaccharide-treated SH-SY5Y cells by sequestering miR-182-5p from ATAT1 and activating NLRP3 inflammasome. | HAGLR aggravates neuropathic pain and promotes inflammatory response and apoptosis of lipopolysaccharide-treated SH-SY5Y cells by sequestering miR-182-5p from ATAT1 and activating NLRP3 inflammasome.
Zhang Q, Zhou L, Xie H, Zhang H, Gao X. | 11/22/2021 |
| LncRNA CHRF aggravates myocardial ischemia/reperfusion injury by enhancing autophagy via modulation of the miR-182-5p/ATG7 pathway. | LncRNA CHRF aggravates myocardial ischemia/reperfusion injury by enhancing autophagy via modulation of the miR-182-5p/ATG7 pathway.
Mo Y, Wu H, Zheng X, Xu L, Liu L, Liu Z. | 07/31/2021 |
| MiR-182 inhibits oxidative stress and epithelial cell apoptosis in lens of cataract rats through PI3K/Akt signaling pathway. | MiR-182 inhibits oxidative stress and epithelial cell apoptosis in lens of cataract rats through PI3K/Akt signaling pathway.
Yao L, Yan H. | 06/26/2021 |
| MicroRNA-182 inhibits osteogenic differentiation of bone marrow mesenchymal stem cells by targeting Smad1. | MicroRNA-182 inhibits osteogenic differentiation of bone marrow mesenchymal stem cells by targeting Smad1.
Zheng HB, Wu M, Zhang G, Chen KL. | 05/22/2021 |
| miR-182 prevented ototoxic deafness induced by co-administration of kanamycin and furosemide in rats. | miR-182 prevented ototoxic deafness induced by co-administration of kanamycin and furosemide in rats.
Chen J, Liu Z, Yan H, Xing W, Mi W, Wang R, Li W, Chen F, Qiu J, Zha D. | 04/24/2021 |
| MiRNA-182 regulates the cardiomyocyte apoptosis in heart failure. | MiRNA-182 regulates the cardiomyocyte apoptosis in heart failure.
Zhou F, Fu WD, Chen L. | 09/26/2020 |
| Validation of sequencing results by real-time PCR confirmed the upregulation of the majority of these miRNAs in tumors, including miR-182, as well as miR-224-5p as the most dysregulated of these miRNAs (over 400-fold). The longitudinal analysis of levels of miR-182 in sera demonstrated significant and persistent increases (5.13-fold; 95% CI: 4.59-5.70). | Serum miR-182 is a predictive biomarker for dichotomization of risk of hepatocellular carcinoma in rats.
Livingstone MC, Johnson NM, Roebuck BD, Kensler TW, Groopman JD., Free PMC Article | 01/25/2020 |
| The study aimed to investigate the impact of miR-182 and FOXO1 on S. japonica-induced hepatic fibrosis. Microarray analysis was performed to screen out differential expressed miRNAs and mRNAs. Rat hepatic fibrosis model and human hepatocellular cell line LX-2 were used to study the effect of miR-182 and FOXO1 | Effect of miR-182 on hepatic fibrosis induced by Schistosomiasis japonica by targeting FOXO1 through PI3K/AKT signaling pathway.
Huang Y, Fan X, Tao R, Song Q, Wang L, Zhang H, Kong H, Huang J. | 10/5/2019 |
| the present study shows that down-regulated miR-182-5p promotes the proliferation and differentiation of osteoblasts in Osteoporosis (OP) rats through Rap1/MAPK signaling pathway activation by up-regulating ADCY6, which may represent a novel target for OP treatment | Decreased microRNA-182-5p helps alendronate promote osteoblast proliferation and differentiation in osteoporosis via the Rap1/MAPK pathway.
Pan BL, Tong ZW, Li SD, Wu L, Liao JL, Yang YX, Li HH, Dai YJ, Li JE, Pan L., Free PMC Article | 07/27/2019 |
| Data suggest that miR-182-5p exhibits potential neuroprotective effects in the cerebral ischemia-reperfusion injury via the regulation of the Toll-like receptor 4 (TLR4)-mediated inflammatory response. | MicroRNA-182-5p attenuates cerebral ischemia-reperfusion injury by targeting Toll-like receptor 4.
Wang J, Xu Z, Chen X, Li Y, Chen C, Wang C, Zhu J, Wang Z, Chen W, Xiao Z, Xu R. | 06/1/2019 |
| Thus, it can be concluded that rno-miR-183-96-182 cluster being significantly up regulated and associated with chronic liver disease might play a role in fibrosis maintenance and progression. A panel of rno-miR-182-5p and ALT being significant predictors of fibrosis might improve histological stratification of fibrosis staging. | Association of rno-miR-183-96-182 cluster with diethyinitrosamine induced liver fibrosis in Wistar rats.
Chandel R, Saxena R, Das A, Kaur J. | 12/22/2018 |
| the knockdown of CIAPIN1 with small interfering RNAs (siRNAs) efficiently abolished the protective effects of miR-182-5p inhibitor on HICA, demonstrating that miR-182-5p plays a pro-apoptotic role in cardiomyocytes under hypoxic conditions by downregulating CIAPIN1. | Inhibition of miR-182-5p protects cardiomyocytes from hypoxia-induced apoptosis by targeting CIAPIN1.
Zhang Y, Fang J, Ma H. | 12/1/2018 |
| miR-182 exacerbated acute kidney injury by targeting and regulation of TCF7L2/Wnt/beta-catenin signaling. | miR-182 enhances acute kidney injury by promoting apoptosis involving the targeting and regulation of TCF7L2/Wnt/β-catenins pathway.
Li H, Ma Y, Chen B, Shi J. | 10/20/2018 |
| A luciferase reporter assay confirmed that SORT1 is the direct target of miR-182. Our study suggests that SORT1 plays a vital role in the development of arterial calcification and is regulated by miR-182. | The miR-182/SORT1 axis regulates vascular smooth muscle cell calcification in vitro and in vivo.
Zhang Z, Jiang W, Yang H, Lin Q, Qin X. | 10/6/2018 |
| results suggest that the retina-enriched miRNAs (miR-183/96/182 cluster and miR-124) could serve as convenient and predictive biomarkers of retinal toxicity in drug development | Editor's Highlight: Plasma miR-183/96/182 Cluster and miR-124 are Promising Biomarkers of Rat Retinal Toxicity.
Peng Q, Collette W 3rd, Giddabasappa A, David J, Twamley M, Kalabat D, Aguirre SA, Huang W. | 02/24/2018 |
| miR-182-3p is a novel smooth muscle cell phenotypic modulator which targets MYADM expression. | Oncological miR-182-3p, a Novel Smooth Muscle Cell Phenotype Modulator, Evidences From Model Rats and Patients.
Sun L, Bai Y, Zhao R, Sun T, Cao R, Wang F, He G, Zhang W, Chen Y, Ye P, Du G. | 06/24/2017 |
| in vivo inhibition of miR-182 by antisense oligonucleotide improved kidney function and morphology after Acute kidney injury. | miR-182-5p Inhibition Ameliorates Ischemic Acute Kidney Injury.
Wilflingseder J, Jelencsics K, Bergmeister H, Sunzenauer J, Regele H, Eskandary F, Reindl-Schwaighofer R, Kainz A, Oberbauer R. | 05/27/2017 |
| These data suggest that miR182 may be a novel smooth muscle cell phenotypic marker and a modulator that may be used to prevent smooth muscle cell dedifferentiation via FGF9/PDGFRbeta signaling. | MicroRNA-182 prevents vascular smooth muscle cell dedifferentiation via FGF9/PDGFRβ signaling.
Dong N, Wang W, Tian J, Xie Z, Lv B, Dai J, Jiang R, Huang D, Fang S, Tian J, Li H, Yu B., Free PMC Article | 04/29/2017 |
| Results reveal a potential molecular regulation of miR-182 on BDNF and the pronounced antidepressant behavioral consequences of this regulation | miR-182 (microRNA-182) suppression in the hippocampus evokes antidepressant-like effects in rats.
Li Y, Li S, Yan J, Wang D, Yin R, Zhao L, Zhu Y, Zhu X. | 09/17/2016 |
| miRNA-182 may be involved in the pathogenesis of circadian rhythm disturbance after hypoxic-ischemic brain damage (HIBD). | [Expression profiles of miRNA-182 and Clock mRNA in the pineal gland of neonatal rats with hypoxic-ischemic brain damage].
Han X, Ding X, Xu LX, Liu MH, Feng X., Free PMC Article | 07/30/2016 |