The Protective Effect of Picroside II on Isoflurane-Induced Neuronal Injury in Rats via Downregulating miR-195. | The Protective Effect of Picroside II on Isoflurane-Induced Neuronal Injury in Rats via Downregulating miR-195. Li H, Du W, Yuan Y, Xue J, Li Q, Wang L. | 07/9/2022 |
MiR-195-5p represses inflammation, apoptosis, oxidative stress, and endoplasmic reticulum stress in sepsis-induced myocardial injury by targeting activating transcription factor 6. | MiR-195-5p represses inflammation, apoptosis, oxidative stress, and endoplasmic reticulum stress in sepsis-induced myocardial injury by targeting activating transcription factor 6. Xia H, Zhao H, Yang W, Luo X, Wei J, Xia H. | 04/16/2022 |
Effects of miR-195 on diabetic nephropathy rats through targeting TLR4 and blocking NF-kappaB pathway. | Effects of miR-195 on diabetic nephropathy rats through targeting TLR4 and blocking NF-κB pathway. Zhu LL, Wang HY, Tang T. | 09/18/2021 |
MiR-195 alleviates ulcerative colitis in rats via MAPK signaling pathway. | MiR-195 alleviates ulcerative colitis in rats via MAPK signaling pathway. Bai XS, Bai G, Tang LD, Li Y, Huan Y, Wang H. | 03/20/2021 |
miR-195-5p alleviates acute kidney injury through repression of inflammation and oxidative stress by targeting vascular endothelial growth factor A. | miR-195-5p alleviates acute kidney injury through repression of inflammation and oxidative stress by targeting vascular endothelial growth factor A. Xu Y, Jiang W, Zhong L, Li H, Bai L, Chen X, Lin Y, Zheng D., Free PMC Article | 03/13/2021 |
High-intensity interval training (HIIT) effectively enhances heart function via miR-195 dependent cardiomyopathy reduction in high-fat high-fructose diet-induced diabetic rats. | High-intensity interval training (HIIT) effectively enhances heart function via miR-195 dependent cardiomyopathy reduction in high-fat high-fructose diet-induced diabetic rats. Khakdan S, Delfan M, Heydarpour Meymeh M, Kazerouni F, Ghaedi H, Shanaki M, Kalaki-Jouybari F, Gorgani-Firuzjaee S, Rahimipour A. | 02/13/2021 |
MiR-195 regulates CD40 to maintain Th17/Treg balance in rats with non-alcoholic fatty liver disease. | MiR-195 regulates CD40 to maintain Th17/Treg balance in rats with non-alcoholic fatty liver disease. Li Y, Jiang HT, Han LB, Xiao L, Gan JH. | 11/21/2020 |
Results provide evidence that miRNA-195 plays a role as an interacting paracrine factor between apoptosis-resistant pulmonary microvascular endothelial cells and pulmonary arterial smooth muscle cells, potentially through the HIF-1a/miRNA-195/ Smad7 pathway. | Anti-apoptosis endothelial cell-secreted microRNA-195-5p promotes pulmonary arterial smooth muscle cell proliferation and migration in pulmonary arterial hypertension. Zeng Z, Yao J, Li Y, Xue Y, Zou Y, Shu Z, Jiao Z. | 10/20/2018 |
The results demonstrated that miRNA-195 activated hepatic stellate cells (HSCs) by targeting Smad7. | MicroRNA-195 Activates Hepatic Stellate Cells In Vitro by Targeting Smad7. Song LY, Ma YT, Wu CF, Wang CJ, Fang WJ, Liu SK., Free PMC Article | 03/17/2018 |
miR-195 is involved in chronic brain hypoperfusion-induced dendritic degeneration and neuron death through activation of the N-APP/DR6/caspase pathway. | MicroRNA-195 prevents dendritic degeneration and neuron death in rats following chronic brain hypoperfusion. Chen X, Jiang XM, Zhao LJ, Sun LL, Yan ML, Tian Y, Zhang S, Duan MJ, Zhao HM, Li WR, Hao YY, Wang LB, Xiong QJ, Ai J., Free PMC Article | 03/10/2018 |
miR-195 downregulation in chronic brain hypoperfusion involved PP2A inactivity, which was mediated by the post-transcriptional regulation PME-1, APP, and beta-site APP cleaving enzyme 1 expression. | Knockdown of microRNA-195 contributes to protein phosphatase-2A inactivation in rats with chronic brain hypoperfusion. Liu CD, Wang Q, Zong DK, Pei SC, Yan Y, Yan ML, Sun LL, Hao YY, Mao M, Xing WJ, Ren H, Ai J. | 10/21/2017 |
identified that miR-195 expression was upregulated in myocardial I/R injury, and miR-195 overexpression may promote cardiomyocyte apoptosis by targeting Bcl-2 and inducing mitochondrial apoptotic pathway | Roles of MicroRNA-195 in cardiomyocyte apoptosis induced by myocardial ischemia-reperfusion injury. Gao CK, Liu H, Cui CJ, Liang ZG, Yao H, Tian Y. | 12/31/2016 |
reduced miR-195 expression partially protects rats from spinal cord injury, primarily by targeting HIF-1alpha. | Decreased miR-195 Expression Protects Rats from Spinal Cord Injury Primarily by Targeting HIF-1α. Tao B, Shi K. | 12/17/2016 |
Our findings demonstrated that the down-regulation of miR-195 plays a key role in the increased vulnerability to dementia via the regulation of multiple targets following chronic brain hypoperfusion | Activation of Cdk5/p25 and tau phosphorylation following chronic brain hypoperfusion in rats involves microRNA-195 down-regulation. Sun LH, Ban T, Liu CD, Chen QX, Wang X, Yan ML, Hu XL, Su XL, Bao YN, Sun LL, Zhao LJ, Pei SC, Jiang XM, Zong DK, Ai J. | 12/19/2015 |
miR-195 regulates SIRT1-mediated tissue damage in diabetic retinopathy | miR-195 regulates SIRT1-mediated changes in diabetic retinopathy. Mortuza R, Feng B, Chakrabarti S. | 12/20/2014 |
A novel pathway regulating neuroinflammation and neuropathic pain is identified with miR-195/autophagy signaling. | Increased miR-195 aggravates neuropathic pain by inhibiting autophagy following peripheral nerve injury. Shi G, Shi J, Liu K, Liu N, Wang Y, Fu Z, Ding J, Jia L, Yuan W. | 11/2/2013 |