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    Mir195 microRNA 195 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100314281, updated on 13-Apr-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    The Protective Effect of Picroside II on Isoflurane-Induced Neuronal Injury in Rats via Downregulating miR-195.

    The Protective Effect of Picroside II on Isoflurane-Induced Neuronal Injury in Rats via Downregulating miR-195.
    Li H, Du W, Yuan Y, Xue J, Li Q, Wang L.

    07/9/2022
    MiR-195-5p represses inflammation, apoptosis, oxidative stress, and endoplasmic reticulum stress in sepsis-induced myocardial injury by targeting activating transcription factor 6.

    MiR-195-5p represses inflammation, apoptosis, oxidative stress, and endoplasmic reticulum stress in sepsis-induced myocardial injury by targeting activating transcription factor 6.
    Xia H, Zhao H, Yang W, Luo X, Wei J, Xia H.

    04/16/2022
    Effects of miR-195 on diabetic nephropathy rats through targeting TLR4 and blocking NF-kappaB pathway.

    Effects of miR-195 on diabetic nephropathy rats through targeting TLR4 and blocking NF-κB pathway.
    Zhu LL, Wang HY, Tang T.

    09/18/2021
    MiR-195 alleviates ulcerative colitis in rats via MAPK signaling pathway.

    MiR-195 alleviates ulcerative colitis in rats via MAPK signaling pathway.
    Bai XS, Bai G, Tang LD, Li Y, Huan Y, Wang H.

    03/20/2021
    miR-195-5p alleviates acute kidney injury through repression of inflammation and oxidative stress by targeting vascular endothelial growth factor A.

    miR-195-5p alleviates acute kidney injury through repression of inflammation and oxidative stress by targeting vascular endothelial growth factor A.
    Xu Y, Jiang W, Zhong L, Li H, Bai L, Chen X, Lin Y, Zheng D., Free PMC Article

    03/13/2021
    High-intensity interval training (HIIT) effectively enhances heart function via miR-195 dependent cardiomyopathy reduction in high-fat high-fructose diet-induced diabetic rats.

    High-intensity interval training (HIIT) effectively enhances heart function via miR-195 dependent cardiomyopathy reduction in high-fat high-fructose diet-induced diabetic rats.
    Khakdan S, Delfan M, Heydarpour Meymeh M, Kazerouni F, Ghaedi H, Shanaki M, Kalaki-Jouybari F, Gorgani-Firuzjaee S, Rahimipour A.

    02/13/2021
    MiR-195 regulates CD40 to maintain Th17/Treg balance in rats with non-alcoholic fatty liver disease.

    MiR-195 regulates CD40 to maintain Th17/Treg balance in rats with non-alcoholic fatty liver disease.
    Li Y, Jiang HT, Han LB, Xiao L, Gan JH.

    11/21/2020
    Results provide evidence that miRNA-195 plays a role as an interacting paracrine factor between apoptosis-resistant pulmonary microvascular endothelial cells and pulmonary arterial smooth muscle cells, potentially through the HIF-1a/miRNA-195/ Smad7 pathway.

    Anti-apoptosis endothelial cell-secreted microRNA-195-5p promotes pulmonary arterial smooth muscle cell proliferation and migration in pulmonary arterial hypertension.
    Zeng Z, Yao J, Li Y, Xue Y, Zou Y, Shu Z, Jiao Z.

    10/20/2018
    The results demonstrated that miRNA-195 activated hepatic stellate cells (HSCs) by targeting Smad7.

    MicroRNA-195 Activates Hepatic Stellate Cells In Vitro by Targeting Smad7.
    Song LY, Ma YT, Wu CF, Wang CJ, Fang WJ, Liu SK., Free PMC Article

    03/17/2018
    miR-195 is involved in chronic brain hypoperfusion-induced dendritic degeneration and neuron death through activation of the N-APP/DR6/caspase pathway.

    MicroRNA-195 prevents dendritic degeneration and neuron death in rats following chronic brain hypoperfusion.
    Chen X, Jiang XM, Zhao LJ, Sun LL, Yan ML, Tian Y, Zhang S, Duan MJ, Zhao HM, Li WR, Hao YY, Wang LB, Xiong QJ, Ai J., Free PMC Article

    03/10/2018
    miR-195 downregulation in chronic brain hypoperfusion involved PP2A inactivity, which was mediated by the post-transcriptional regulation PME-1, APP, and beta-site APP cleaving enzyme 1 expression.

    Knockdown of microRNA-195 contributes to protein phosphatase-2A inactivation in rats with chronic brain hypoperfusion.
    Liu CD, Wang Q, Zong DK, Pei SC, Yan Y, Yan ML, Sun LL, Hao YY, Mao M, Xing WJ, Ren H, Ai J.

    10/21/2017
    identified that miR-195 expression was upregulated in myocardial I/R injury, and miR-195 overexpression may promote cardiomyocyte apoptosis by targeting Bcl-2 and inducing mitochondrial apoptotic pathway

    Roles of MicroRNA-195 in cardiomyocyte apoptosis induced by myocardial ischemia-reperfusion injury.
    Gao CK, Liu H, Cui CJ, Liang ZG, Yao H, Tian Y.

    12/31/2016
    reduced miR-195 expression partially protects rats from spinal cord injury, primarily by targeting HIF-1alpha.

    Decreased miR-195 Expression Protects Rats from Spinal Cord Injury Primarily by Targeting HIF-1α.
    Tao B, Shi K.

    12/17/2016
    Our findings demonstrated that the down-regulation of miR-195 plays a key role in the increased vulnerability to dementia via the regulation of multiple targets following chronic brain hypoperfusion

    Activation of Cdk5/p25 and tau phosphorylation following chronic brain hypoperfusion in rats involves microRNA-195 down-regulation.
    Sun LH, Ban T, Liu CD, Chen QX, Wang X, Yan ML, Hu XL, Su XL, Bao YN, Sun LL, Zhao LJ, Pei SC, Jiang XM, Zong DK, Ai J.

    12/19/2015
    miR-195 regulates SIRT1-mediated tissue damage in diabetic retinopathy

    miR-195 regulates SIRT1-mediated changes in diabetic retinopathy.
    Mortuza R, Feng B, Chakrabarti S.

    12/20/2014
    A novel pathway regulating neuroinflammation and neuropathic pain is identified with miR-195/autophagy signaling.

    Increased miR-195 aggravates neuropathic pain by inhibiting autophagy following peripheral nerve injury.
    Shi G, Shi J, Liu K, Liu N, Wang Y, Fu Z, Ding J, Jia L, Yuan W.

    11/2/2013
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