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    HOXB13 homeobox B13 [ Homo sapiens (human) ]

    Gene ID: 10481, updated on 5-Mar-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Characterization of HOXB13 expression patterns in localized and metastatic castration-resistant prostate cancer.

    Characterization of HOXB13 expression patterns in localized and metastatic castration-resistant prostate cancer.
    Patel RA, Sayar E, Coleman I, Roudier MP, Hanratty B, Low JY, Jaiswal N, Ajkunic A, Dumpit R, Ercan C, Salama N, O'Brien VP, Isaacs WB, Epstein JI, De Marzo AM, Trock BJ, Luo J, Brennen WN, Tretiakova M, Vakar-Lopez F, True LD, Goodrich DW, Corey E, Morrissey C, Nelson PS, Hurley PJ, Gulati R, Haffner MC.,

    12/16/2023
    Hierarchical Phosphorylation of HOXB13 by mTOR Dictates Its Activity and Oncogenic Function in Prostate Cancer.

    Hierarchical Phosphorylation of HOXB13 by mTOR Dictates Its Activity and Oncogenic Function in Prostate Cancer.
    Chen Y, Dufour CR, Han L, Li T, Xia H, Giguère V., Free PMC Article

    10/5/2023
    Immunoreactivity of HOXB13 in Neuroendocrine Neoplasms Is a Sensitive and Specific Marker of Rectal Well-Differentiated Neuroendocrine Tumors.

    Immunoreactivity of HOXB13 in Neuroendocrine Neoplasms Is a Sensitive and Specific Marker of Rectal Well-Differentiated Neuroendocrine Tumors.
    Soukup J, Manethova M, Stejskal V, Hornychova H, Cesak T, Netuka D, Ryska A, Gabalec F.

    09/23/2023
    Germline Variants in DNA Damage Repair Genes and HOXB13 Among Black Patients With Early-Onset Prostate Cancer.

    Germline Variants in DNA Damage Repair Genes and HOXB13 Among Black Patients With Early-Onset Prostate Cancer.
    Trendowski MR, Sample C, Baird T, Sadeghpour A, Moon D, Ruterbusch JJ, Beebe-Dimmer JL, Cooney KA., Free PMC Article

    12/17/2022
    Acetylated HOXB13 Regulated Super Enhancer Genes Define Therapeutic Vulnerabilities of Castration-Resistant Prostate Cancer.

    Acetylated HOXB13 Regulated Super Enhancer Genes Define Therapeutic Vulnerabilities of Castration-Resistant Prostate Cancer.
    Nguyen DT, Yang W, Renganathan A, Weimholt C, Angappulige DH, Nguyen T, Sprung RW, Andriole GL, Kim EH, Mahajan NP, Mahajan K., Free PMC Article

    10/1/2022
    Excessive activation of HOXB13/PIMREG axis promotes hepatocellular carcinoma progression and drug resistance.

    Excessive activation of HOXB13/PIMREG axis promotes hepatocellular carcinoma progression and drug resistance.
    Tang C, Qiu S, Mou W, Xu J, Wang P.

    08/27/2022
    Comprehensive network analysis of dysregulated genes revealed MNX1-AS1/hsa-miR-4697-3p/HOXB13 axis in ovarian cancer chemotherapy response.

    Comprehensive network analysis of dysregulated genes revealed MNX1-AS1/hsa-miR-4697-3p/HOXB13 axis in ovarian cancer chemotherapy response.
    Wu A, Liu J, Zhang X, Niu C, Shu G, Yin G., Free PMC Article

    08/13/2022
    HOXB13 suppresses de novo lipogenesis through HDAC3-mediated epigenetic reprogramming in prostate cancer.

    HOXB13 suppresses de novo lipogenesis through HDAC3-mediated epigenetic reprogramming in prostate cancer.
    Lu X, Fong KW, Gritsina G, Wang F, Baca SC, Brea LT, Berchuck JE, Spisak S, Ross J, Morrissey C, Corey E, Chandel NS, Catalona WJ, Yang X, Freedman ML, Zhao JC, Yu J., Free PMC Article

    05/28/2022
    [miR-20a-5p inhibits proliferation of lung cancer A549 cells by down-regulating HOXB13].

    [miR-20a-5p inhibits proliferation of lung cancer A549 cells by down-regulating HOXB13].
    Liu H, Wang J, Shen J, Wu X, Li Y., Free PMC Article

    05/14/2022
    A Rare Germline HOXB13 Variant Contributes to Risk of Prostate Cancer in Men of African Ancestry.

    A Rare Germline HOXB13 Variant Contributes to Risk of Prostate Cancer in Men of African Ancestry.
    Darst BF, Hughley R, Pfennig A, Hazra U, Fan C, Wan P, Sheng X, Xia L, Andrews C, Chen F, Berndt SI, Kote-Jarai Z, Govindasami K, Bensen JT, Ingles SA, Rybicki BA, Nemesure B, John EM, Fowke JH, Huff CD, Strom SS, Isaacs WB, Park JY, Zheng W, Ostrander EA, Walsh PC, Carpten J, Sellers TA, Yamoah K, Murphy AB, Sanderson M, Crawford DC, Gapstur SM, Bush WS, Aldrich MC, Cussenot O, Petrovics G, Cullen J, Neslund-Dudas C, Kittles RA, Xu J, Stern MC, Chokkalingam AP, Multigner L, Parent ME, Menegaux F, Cancel-Tassin G, Kibel AS, Klein EA, Goodman PJ, Stanford JL, Drake BF, Hu JJ, Clark PE, Blanchet P, Casey G, Hennis AJM, Lubwama A, Thompson IM Jr, Leach RJ, Gundell SM, Pooler L, Mohler JL, Fontham ETH, Smith GJ, Taylor JA, Brureau L, Blot WJ, Biritwum R, Tay E, Truelove A, Niwa S, Tettey Y, Varma R, McKean-Cowdin R, Torres M, Jalloh M, Magueye Gueye S, Niang L, Ogunbiyi O, Oladimeji Idowu M, Popoola O, Adebiyi AO, Aisuodionoe-Shadrach OI, Nwegbu M, Adusei B, Mante S, Darkwa-Abrahams A, Yeboah ED, Mensah JE, Anthony Adjei A, Diop H, Cook MB, Chanock SJ, Watya S, Eeles RA, Chiang CWK, Lachance J, Rebbeck TR, Conti DV, Haiman CA., Free PMC Article

    04/30/2022
    The HOXB13 variant X285K is associated with clinical significance and early age at diagnosis in African American prostate cancer patients.

    The HOXB13 variant X285K is associated with clinical significance and early age at diagnosis in African American prostate cancer patients.
    Na R, Wei J, Sample CJ, Gielzak M, Choi S, Cooney KA, Rabizadeh D, Walsh PC, Zheng LS, Xu J, Isaacs WB., Free PMC Article

    03/12/2022
    Somatic HOXB13 Expression Correlates with Metastatic Progression in Men with Localized Prostate Cancer Following Radical Prostatectomy.

    Somatic HOXB13 Expression Correlates with Metastatic Progression in Men with Localized Prostate Cancer Following Radical Prostatectomy.
    Weiner AB, Faisal FA, Davicioni E, Karnes RJ, Griend DJV, Lotan TL, Schaeffer EM., Free PMC Article

    02/5/2022
    Loss of 9p21 Regulatory Hub Promotes Kidney Cancer Progression by Upregulating HOXB13.

    Loss of 9p21 Regulatory Hub Promotes Kidney Cancer Progression by Upregulating HOXB13.
    Baietti MF, Zhao P, Crowther J, Sewduth RN, De Troyer L, Debiec-Rychter M, Sablina AA.

    01/29/2022
    HOXB13 suppresses proliferation, migration and invasion, and promotes apoptosis of gastric cancer cells through transcriptional activation of VGLL4 to inhibit the involvement of TEAD4 in the Hippo signaling pathway.

    HOXB13 suppresses proliferation, migration and invasion, and promotes apoptosis of gastric cancer cells through transcriptional activation of VGLL4 to inhibit the involvement of TEAD4 in the Hippo signaling pathway.
    Geng H, Liu G, Hu J, Li J, Wang D, Zou S, Xu X., Free PMC Article

    01/15/2022
    Neuroendocrine prostate cancer has distinctive, non-prostatic HOX code that is represented by the loss of HOXB13 expression.

    Neuroendocrine prostate cancer has distinctive, non-prostatic HOX code that is represented by the loss of HOXB13 expression.
    Cheng S, Yang S, Shi Y, Shi R, Yeh Y, Yu X., Free PMC Article

    11/22/2021
    Prostate cancer risk variants of the HOXB genetic locus.

    Prostate cancer risk variants of the HOXB genetic locus.
    Dupont WD, Breyer JP, Johnson SH, Plummer WD, Smith JR., Free PMC Article

    11/13/2021
    Upregulated long noncoding RNA LincIN promotes tumor progression via the regulation of nuclear factor 90/microRNA7/HOXB13 in esophageal squamous cell carcinoma.

    Upregulated long non‑coding RNA LincIN promotes tumor progression via the regulation of nuclear factor 90/microRNA‑7/HOXB13 in esophageal squamous cell carcinoma.
    Tan Z, Zhou P, Zhu Z, Wang Y, Guo Z, Shen M, Xiao Y, Shen W, Wu D., Free PMC Article

    11/13/2021
    HOXB13 and TFF3 can contribute to the prognostic stratification of prostate adenocarcinoma.

    HOXB13 and TFF3 can contribute to the prognostic stratification of prostate adenocarcinoma.
    Timofte AD, Giuşcă SE, Lozneanu L, Manole MB, Prutianu I, Gafton B, Rusu A, Căruntu ID., Free PMC Article

    10/30/2021
    Differential expression of NKX 3.1 and HOXB 13 in bone metastases originating from prostatic carcinoma among the Egyptian males.

    Differential expression of NKX 3.1 and HOXB 13 in bone metastases originating from prostatic carcinoma among the Egyptian males.
    Abouhashem NS, Salah S.

    08/21/2021
    Long Noncoding RNA HOXA11-AS and Transcription Factor HOXB13 Modulate the Expression of Bone Metastasis-Related Genes in Prostate Cancer.

    Long Noncoding RNA HOXA11-AS and Transcription Factor HOXB13 Modulate the Expression of Bone Metastasis-Related Genes in Prostate Cancer.
    Misawa A, Kondo Y, Takei H, Takizawa T., Free PMC Article

    07/31/2021
    LncRNA SNHG14 regulates the DDP-resistance of non-small cell lung cancer cell through miR-133a/HOXB13 pathway.

    LncRNA SNHG14 regulates the DDP-resistance of non-small cell lung cancer cell through miR-133a/HOXB13 pathway.
    Xu L, Xu Y, Yang M, Li J, Xu F, Chen BL., Free PMC Article

    07/17/2021
    HOXB13 promotes gastric cancer cell migration and invasion via IGF-1R upregulation and subsequent activation of PI3K/AKT/mTOR signaling pathway.

    HOXB13 promotes gastric cancer cell migration and invasion via IGF-1R upregulation and subsequent activation of PI3K/AKT/mTOR signaling pathway.
    Guo C, Chu H, Gong Z, Zhang B, Li C, Chen J, Huang L.

    07/10/2021
    The HOXB13 p.Gly84Glu variant observed in an extended five generation high-risk prostate cancer pedigree supports risk association for multiple cancer sites.

    The HOXB13 p.Gly84Glu variant observed in an extended five generation high-risk prostate cancer pedigree supports risk association for multiple cancer sites.
    Cannon-Albright LA, Stevens J, Teerlink CC, Agarwal N., Free PMC Article

    06/26/2021
    Germline HOXB13 G84E mutation carriers and risk to twenty common types of cancer: results from the UK Biobank.

    Germline HOXB13 G84E mutation carriers and risk to twenty common types of cancer: results from the UK Biobank.
    Wei J, Shi Z, Na R, Wang CH, Resurreccion WK, Zheng SL, Hulick PJ, Cooney KA, Helfand BT, Isaacs WB, Xu J., Free PMC Article

    03/28/2021
    HOXB13 controls cell state through super-enhancers.

    HOXB13 controls cell state through super-enhancers.
    Aspuria PJ, Cheon DJ, Gozo MC, Beach JA, Recouvreux MS, Walts AE, Karlan BY, Orsulic S.

    01/9/2021
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