| Importin 7 enhances protective autophagy induced by nuclear translocation of homeobox A10 in oral squamous cell carcinoma. | Importin 7 enhances protective autophagy induced by nuclear translocation of homeobox A10 in oral squamous cell carcinoma.
Chen S, Pan J. | 05/3/2024 |
| IPO7 promotes pancreatic cancer progression via regulating ERBB pathway. | IPO7 promotes pancreatic cancer progression via regulating ERBB pathway.
Li M, Xu D, Zhan Y, Tan S., Free PMC Article | 06/11/2022 |
| The sequence [EKRKI(E/R)(K/L/R/S/T)] is a nuclear localization signal for importin 7 binding (NLS7). | The sequence [EKRKI(E/R)(K/L/R/S/T)] is a nuclear localization signal for importin 7 binding (NLS7).
Panagiotopoulos AA, Polioudaki C, Ntallis SG, Dellis D, Notas G, Panagiotidis CA, Theodoropoulos PA, Castanas E, Kampa M. | 07/3/2021 |
| Pediatric ependymoma: GNAO1, ASAH1, IMMT and IPO7 protein expression and 5-year prognosis correlation. | Pediatric ependymoma: GNAO1, ASAH1, IMMT and IPO7 protein expression and 5-year prognosis correlation.
Pérez-Ramírez M, García-Méndez A, Siordia-Reyes AG, Chavarría A, Gómez C, García-Hernández N. | 11/21/2020 |
| AKT and 14-3-3 proteins down-regulate the activity of several BCR-associated components, including BTK, BLNK and SYK and also inhibit SYK's interaction with Importin 7 | Protein kinase B (AKT) regulates SYK activity and shuttling through 14-3-3 and importin 7.
Mohammad DK, Nore BF, Gustafsson MO, Mohamed AJ, Smith CIE. | 11/26/2017 |
| Importins, Impbeta, Kapbeta2, Imp4, Imp5, Imp7, Imp9, and Impalpha, show the H3 tail binding more tightly than the H4 tail. The H3 tail binds Kapbeta2 and Imp5 with KD values of 77 and 57 nm, respectively, and binds the other five Importins more weakly. | Recognition Elements in the Histone H3 and H4 Tails for Seven Different Importins.
Soniat M, Cağatay T, Chook YM., Free PMC Article | 05/20/2017 |
| Depletion of IPO7 by IPO7 siRNA reduced nuclear accumulation of GLI1. In addition, FOXM1 induced nuclear import of GLI1 by promoting IPO7 expression. | Forkhead Box M1 Is Essential for Nuclear Localization of Glioma-associated Oncogene Homolog 1 in Glioblastoma Multiforme Cells by Promoting Importin-7 Expression.
Xue J, Zhou A, Tan C, Wu Y, Lee HT, Li W, Xie K, Huang S., Free PMC Article | 10/24/2015 |
| Importin 7 as a soluble nuclear transport factor that is required for efficient import of the protein component of human telomerase. | Importin 7 and Nup358 promote nuclear import of the protein component of human telomerase.
Frohnert C, Hutten S, Wälde S, Nath A, Kehlenbach RH., Free PMC Article | 01/3/2015 |
| Importin 7 contributes to the regulation of androgen receptor import by restraining import until androgen is detected in the cytoplasm. | Androgen induces a switch from cytoplasmic retention to nuclear import of the androgen receptor.
Ni L, Llewellyn R, Kesler CT, Kelley JB, Spencer A, Snow CJ, Shank L, Paschal BM., Free PMC Article | 02/1/2014 |
| imp7 is a part of an intrinsic pathway that promotes nuclear import of exogenous and endogenous DNA in mammalian cells. | Importin-7 mediates nuclear trafficking of DNA in mammalian cells.
Dhanoya A, Wang T, Keshavarz-Moore E, Fassati A, Chain BM., Free PMC Article | 06/15/2013 |
| Importin 7 (IPO7)is regulated positively by c-Myc and negatively by p53. | Importin 7 and exportin 1 link c-Myc and p53 to regulation of ribosomal biogenesis.
Golomb L, Bublik DR, Wilder S, Nevo R, Kiss V, Grabusic K, Volarevic S, Oren M., Free PMC Article | 04/7/2012 |
| essential for Egr-1 nuclear translocation | Nuclear import of early growth response-1 involves importin-7 and the novel nuclear localization signal serine-proline-serine.
Chen J, Liu MY, Parish CR, Chong BH, Khachigian L. | 10/8/2011 |
| Data show that ARHI could compete for Ran-importin binding and induce disruption of importin-binding to cargo proteins, including STAT3. | ARHI (DIRAS3), an imprinted tumour suppressor gene, binds to importins and blocks nuclear import of cargo proteins.
Huang S, Chang IS, Lin W, Ye W, Luo RZ, Lu Z, Lu Y, Zhang K, Liao WS, Tao T, Bast RC Jr, Chen X, Yu Y., Free PMC Article | 03/8/2010 |
| importins 4 and 7 accomplish nuclear import of HIF-1alpha more efficiently than the classical importin alpha/beta NLS receptor | Transport of hypoxia-inducible factor HIF-1alpha into the nucleus involves importins 4 and 7.
Chachami G, Paraskeva E, Mingot JM, Braliou GG, Görlich D, Simos G. | 01/21/2010 |
| Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) | A genome-wide association study of hypertension and blood pressure in African Americans.
Adeyemo A, Gerry N, Chen G, Herbert A, Doumatey A, Huang H, Zhou J, Lashley K, Chen Y, Christman M, Rotimi C., Free PMC Article | 12/2/2009 |
| Although imp7 may not be essential for HIV-1 infection, our results suggest that imp7 facilitates nuclear trafficking of DNA and that HIV-1 exploits imp7 to maximize nuclear import of its DNA genome. | HIV-1 exploits importin 7 to maximize nuclear import of its DNA genome.
Zaitseva L, Cherepanov P, Leyens L, Wilson SJ, Rasaiyaah J, Fassati A., Free PMC Article | 01/21/2010 |
| TGF-beta-induced and basal state spontaneous nuclear import of Smad4 require importin 7 and 8. | Preferential utilization of Imp7/8 in nuclear import of Smads.
Yao X, Chen X, Cottonham C, Xu L., Free PMC Article | 01/21/2010 |
| When the import assay was performed with a low concentration of each importin- subtype, NPI2/importin-7 elicited more efficient transport activity of the human herpesvirus 6 U69 protein | Characterization of the human herpesvirus 6 U69 gene product and identification of its nuclear localization signal.
Isegawa Y, Miyamoto Y, Yasuda Y, Semi K, Tsujimura K, Fukunaga R, Ohshima A, Horiguchi Y, Yoneda Y, Sugimoto N., Free PMC Article | 01/21/2010 |
| These results identify EZI as a novel cargo protein for importin-7 and demonstrate a nucleocytoplasmic shuttling mechanism that is mediated by importin-7-dependent nuclear localization and CRM1-independent nuclear export. | Nucleocytoplasmic shuttling of the zinc finger protein EZI Is mediated by importin-7-dependent nuclear import and CRM1-independent export mechanisms.
Saijou E, Itoh T, Kim KW, Iemura S, Natsume T, Miyajima A. | 01/21/2010 |
| role of IMP7 in nuclear transport of H1 histones | The requirement of H1 histones for a heterodimeric nuclear import receptor.
Bäuerle M, Doenecke D, Albig W. | 01/21/2010 |
| Nuclear import of HIV-1 intracellular reverse transcription is mediated by IPO7. | Nuclear import of HIV-1 intracellular reverse transcription complexes is mediated by importin 7.
Fassati A, Görlich D, Harrison I, Zaytseva L, Mingot JM., Free PMC Article | 01/21/2010 |