m[6]A-dependent upregulation of DDX21 by super-enhancer-driven IGF2BP2 and IGF2BP3 facilitates progression of acute myeloid leukaemia. | m(6)A-dependent upregulation of DDX21 by super-enhancer-driven IGF2BP2 and IGF2BP3 facilitates progression of acute myeloid leukaemia. Zhao Y, Zhou Y, Qian Y, Wei W, Lin X, Mao S, Sun J, Jin J., Free PMC Article | 04/8/2024 |
Knockdown of RNA-binding protein IMP3 suppresses oral squamous cell carcinoma proliferation by destabilizing E2F5 transcript. | Knockdown of RNA-binding protein IMP3 suppresses oral squamous cell carcinoma proliferation by destabilizing E2F5 transcript. Wang Z, Zhang H, Li F, Huang C., Free PMC Article | 03/26/2024 |
NONO promotes gallbladder cancer cell proliferation by enhancing oncogenic RNA splicing of DLG1 through interaction with IGF2BP3/RBM14. | NONO promotes gallbladder cancer cell proliferation by enhancing oncogenic RNA splicing of DLG1 through interaction with IGF2BP3/RBM14. Yang ZY, Zhao C, Liu SL, Pan LJ, Zhu YD, Zhao JW, Wang HK, Ye YY, Qiang J, Shi LQ, Mei JW, Xie Y, Gong W, Shu YJ, Dong P, Xiang SS. | 03/26/2024 |
Depletion of the N[6]-Methyladenosine (m6A) reader protein IGF2BP3 induces ferroptosis in glioma by modulating the expression of GPX4. | Depletion of the N(6)-Methyladenosine (m6A) reader protein IGF2BP3 induces ferroptosis in glioma by modulating the expression of GPX4. Deng L, Di Y, Chen C, Xia J, Lei B, Li N, Zhang Q., Free PMC Article | 03/14/2024 |
The RNA m[6]A reader IGF2BP3 regulates NFAT1/IRF1 axis-mediated anti-tumor activity in gastric cancer. | The RNA m(6)A reader IGF2BP3 regulates NFAT1/IRF1 axis-mediated anti-tumor activity in gastric cancer. Ge L, Rui Y, Wang C, Wu Y, Wang H, Wang J., Free PMC Article | 03/12/2024 |
Insulin-like growth factor 2 mRNA-binding protein 3 enhanced melanoma migration through regulation of AKT1 and RELA expression. | Insulin-like growth factor 2 mRNA-binding protein 3 enhanced melanoma migration through regulation of AKT1 and RELA expression. Sheen YS, Syu YJ, Chang YC, Hsieh PH, Liao YH, Lin MH, Chen CY, Chu CY, Chu CY. | 03/1/2024 |
IGF2BP3 enhances lipid metabolism in cervical cancer by upregulating the expression of SCD. | IGF2BP3 enhances lipid metabolism in cervical cancer by upregulating the expression of SCD. Han C, Hu C, Liu T, Sun Y, Hu F, He Y, Zhang J, Chen J, Ding J, Fan J, Zhang X, Wang J, Qiao X, Jiang D, Yang K, Yang S., Free PMC Article | 02/21/2024 |
Regulation of ULK1 by WTAP/IGF2BP3 axis enhances mitophagy and progression in epithelial ovarian cancer. | Regulation of ULK1 by WTAP/IGF2BP3 axis enhances mitophagy and progression in epithelial ovarian cancer. Wang J, Zheng F, Wang D, Yang Q., Free PMC Article | 02/21/2024 |
Hypoxia increases the biogenesis of IGF2BP3-bound circular RNAs. | Hypoxia increases the biogenesis of IGF2BP3-bound circular RNAs. Kaushik K, Kumar H, Mehta S, Palanichamy JK. | 02/13/2024 |
Association of the m[6] A reader IGF2BP3 with tumor progression and brain-specific metastasis in breast cancer. | Association of the m(6) A reader IGF2BP3 with tumor progression and brain-specific metastasis in breast cancer. Li Y, Cao J, Wang J, Wu W, Jiang L, Sun X. | 02/5/2024 |
circRARS synergises with IGF2BP3 to regulate RNA methylation recognition to promote tumour progression in renal cell carcinoma. | circRARS synergises with IGF2BP3 to regulate RNA methylation recognition to promote tumour progression in renal cell carcinoma. Liu Y, Chen K, Shou Y, Li S, Wang J, Zhang Q, Huang Z, Xu J, Li M, Liu D, Liang H, Yang H, Zhang X., Free PMC Article | 12/20/2023 |
The m6A reader IGF2BP3 preserves NOTCH3 mRNA stability to sustain Notch3 signaling and promote tumor metastasis in nasopharyngeal carcinoma. | The m6A reader IGF2BP3 preserves NOTCH3 mRNA stability to sustain Notch3 signaling and promote tumor metastasis in nasopharyngeal carcinoma. Chen B, Huang R, Xia T, Wang C, Xiao X, Lu S, Chen X, Ouyang Y, Deng X, Miao J, Zhao C, Wang L., Free PMC Article | 11/30/2023 |
The IGF2BP3-COPS7B Axis Facilitates mRNA Translation to Drive Colorectal Cancer Progression. | The IGF2BP3-COPS7B Axis Facilitates mRNA Translation to Drive Colorectal Cancer Progression. Tang J, Wang S, Weng M, Guo Q, Ren L, He Y, Cui Z, Cong M, Qin M, Yu J, Su R, Li X. | 11/6/2023 |
Parkin regulates IGF2BP3 through ubiquitination in the tumourigenesis of cervical cancer. | Parkin regulates IGF2BP3 through ubiquitination in the tumourigenesis of cervical cancer. Sun X, Ye G, Li J, Shou H, Bai G, Zhang J., Free PMC Article | 10/30/2023 |
IGF2BP3 mediates the mRNA degradation of NF1 to promote triple-negative breast cancer progression via an m6A-dependent manner. | IGF2BP3 mediates the mRNA degradation of NF1 to promote triple-negative breast cancer progression via an m6A-dependent manner. Zhang X, Shi L, Sun HD, Wang ZW, Xu F, Wei JF, Ding Q., Free PMC Article | 09/29/2023 |
RNA N6-methyladenosine reader IGF2BP3 promotes acute myeloid leukemia progression by controlling stabilization of EPOR mRNA. | RNA N6-methyladenosine reader IGF2BP3 promotes acute myeloid leukemia progression by controlling stabilization of EPOR mRNA. Fan J, Zhuang M, Fan W, Hou M., Free PMC Article | 09/27/2023 |
Extracellular vesicle-associated IGF2BP3 tunes Ewing sarcoma cell migration and affects PI3K/Akt pathway in neighboring cells. | Extracellular vesicle-associated IGF2BP3 tunes Ewing sarcoma cell migration and affects PI3K/Akt pathway in neighboring cells. Mancarella C, Giusti V, Caldoni G, Laginestra MA, Parra A, Toracchio L, Giordano G, Roncuzzi L, Piazzi M, Blalock W, Columbaro M, De Feo A, Scotlandi K., Free PMC Article | 09/20/2023 |
IGF2BP3-EGFR-AKT axis promotes breast cancer MDA-MB-231 cell growth. | IGF2BP3-EGFR-AKT axis promotes breast cancer MDA-MB-231 cell growth. Jing X, Han C, Li Q, Li F, Zhang J, Jiang Q, Zhao F, Guo C, Chen J, Jiang T, Wang X, Chen Y, Huang C. | 09/18/2023 |
IGF2BP3 promotes the progression of colorectal cancer and mediates cetuximab resistance by stabilizing EGFR mRNA in an m[6]A-dependent manner. | IGF2BP3 promotes the progression of colorectal cancer and mediates cetuximab resistance by stabilizing EGFR mRNA in an m(6)A-dependent manner. Chen LJ, Liu HY, Xiao ZY, Qiu T, Zhang D, Zhang LJ, Han FY, Chen GJ, Xu XM, Zhu JH, Ding YQ, Wang SY, Ye YP, Jiao HL., Free PMC Article | 09/11/2023 |
Acyl-CoA Medium-Chain Synthetase-3 (ACSM3) Is Regulated by Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3) and Inhibits Proliferation, Motility and Stem Cell Properties of Breast Invasive Carcinoma. | Acyl-CoA Medium-Chain Synthetase-3 (ACSM3) Is Regulated by Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3) and Inhibits Proliferation, Motility and Stem Cell Properties of Breast Invasive Carcinoma. Zhu W, Wei X, Fang M. | 08/30/2023 |
LncRNA FOXD3-AS1/miR-128-3p axis-mediated IGF2BP3 in glioma stimulates cancer angiogenesis and progression. | LncRNA FOXD3-AS1/miR-128-3p axis-mediated IGF2BP3 in glioma stimulates cancer angiogenesis and progression. Zhao H, Wang Y, Liang C, Xie M. | 08/19/2023 |
A novel tumour enhancer function of Insulin-like growth factor II mRNA-binding protein 3 in colorectal cancer. | A novel tumour enhancer function of Insulin-like growth factor II mRNA-binding protein 3 in colorectal cancer. Di Fusco D, Di Grazia A, Di Maggio G, Segreto MT, Iannucci A, Maresca C, De Stefano A, Sica G, Stolfi C, Monteleone G, Monteleone I., Free PMC Article | 08/10/2023 |
m[6] A-Dependent Modulation via IGF2BP3/MCM5/Notch Axis Promotes Partial EMT and LUAD Metastasis. | m(6) A-Dependent Modulation via IGF2BP3/MCM5/Notch Axis Promotes Partial EMT and LUAD Metastasis. Yang X, Bai Q, Chen W, Liang J, Wang F, Gu W, Liu L, Li Q, Chen Z, Zhou A, Long J, Tian H, Wu J, Ding X, Zhou N, Li M, Yang Y, Cai J., Free PMC Article | 07/28/2023 |
Bile duct adenoma and small-sized small duct type intrahepatic cholangiocarcinoma show distinct differences in genetic alterations, expression of IMP3 and EZH2 and stromal and inflammatory components. | Bile duct adenoma and small-sized small duct type intrahepatic cholangiocarcinoma show distinct differences in genetic alterations, expression of IMP3 and EZH2 and stromal and inflammatory components. Sasaki M, Sato Y, Nakanuma Y. | 07/27/2023 |
Metabolic Reprogramming Driven by IGF2BP3 Promotes Acquired Resistance to EGFR Inhibitors in Non-Small Cell Lung Cancer. | Metabolic Reprogramming Driven by IGF2BP3 Promotes Acquired Resistance to EGFR Inhibitors in Non-Small Cell Lung Cancer. Lin Z, Li J, Zhang J, Feng W, Lu J, Ma X, Ding W, Ouyang S, Lu J, Yue P, Wan G, Liu P, Zhang X. | 07/7/2023 |