| Whole-exome sequencing combined with postoperative data identify c.1614dup (CAMKK2) as a novel candidate monogenic obesity variant. | Whole-exome sequencing combined with postoperative data identify c.1614dup (CAMKK2) as a novel candidate monogenic obesity variant.
Wang Y, Yang C, Wen J, Ju L, Ren Z, Zhang T, Liu Y., Free PMC Article | 03/14/2024 |
| CaMKK2 as an emerging treatment target for bipolar disorder. | CaMKK2 as an emerging treatment target for bipolar disorder.
Kaiser J, Nay K, Horne CR, McAloon LM, Fuller OK, Muller AG, Whyte DG, Means AR, Walder K, Berk M, Hannan AJ, Murphy JM, Febbraio MA, Gundlach AL, Scott JW., Free PMC Article | 03/12/2024 |
| Targeting CaMKK2 Inhibits Actin Cytoskeletal Assembly to Suppress Cancer Metastasis. | Targeting CaMKK2 Inhibits Actin Cytoskeletal Assembly to Suppress Cancer Metastasis.
Mukherjee D, Previs RA, Haines C, Al Abo M, Juras PK, Strickland KC, Chakraborty B, Artham S, Whitaker RS, Hebert K, Fontenot J, Patierno SR, Freedman JA, Lau FH, Burow ME, Chang CY, McDonnell DP., Free PMC Article | 09/6/2023 |
| Expression in skin biopsies supports genetic evidence linking CAMKK2, P2X7R and P2X4R with HIV-associated sensory neuropathy. | Expression in skin biopsies supports genetic evidence linking CAMKK2, P2X7R and P2X4R with HIV-associated sensory neuropathy.
Gaff J, Octaviana F, Jackaman C, Kamerman P, Papadimitriou J, Lee S, Mountford J, Price P., Free PMC Article | 08/10/2023 |
| The role of CaMKK2 in Golgi-associated vesicle trafficking. | The role of CaMKK2 in Golgi-associated vesicle trafficking.
Kennedy G, Gibson O, T O'Hare D, Mills IG, Evergren E., Free PMC Article | 02/28/2023 |
| Neuronal CaMKK2 promotes immunosuppression and checkpoint blockade resistance in glioblastoma. | Neuronal CaMKK2 promotes immunosuppression and checkpoint blockade resistance in glioblastoma.
Tomaszewski WH, Waibl-Polania J, Chakraborty M, Perera J, Ratiu J, Miggelbrink A, McDonnell DP, Khasraw M, Ashley DM, Fecci PE, Racioppi L, Sanchez-Perez L, Gunn MD, Sampson JH., Free PMC Article | 11/5/2022 |
| Traumatic-noise-induced hair cell death and hearing loss is mediated by activation of CaMKKbeta. | Traumatic-noise-induced hair cell death and hearing loss is mediated by activation of CaMKKβ.
Wu F, Hill K, Fang Q, He Z, Zheng H, Wang X, Xiong H, Sha SH., Free PMC Article | 04/30/2022 |
| Brief Report: Polymorphisms in CAMKK2 may Influence Domain-Specific Neurocognitive Function in HIV+ Indonesians Receiving ART. | Brief Report: Polymorphisms in CAMKK2 may Influence Domain-Specific Neurocognitive Function in HIV+ Indonesians Receiving ART.
Gaff J, Estiasari R, Diafiri D, Halstrom S, Kamerman P, Price P. | 03/12/2022 |
| CAMKK2 regulates mitochondrial function by controlling succinate dehydrogenase expression, post-translational modification, megacomplex assembly, and activity in a cell-type-specific manner. | CAMKK2 regulates mitochondrial function by controlling succinate dehydrogenase expression, post-translational modification, megacomplex assembly, and activity in a cell-type-specific manner.
Sabbir MG, Taylor CG, Zahradka P., Free PMC Article | 02/26/2022 |
| CaMKK2 facilitates Golgi-associated vesicle trafficking to sustain cancer cell proliferation. | CaMKK2 facilitates Golgi-associated vesicle trafficking to sustain cancer cell proliferation.
Stewart LM, Gerner L, Rettel M, Stein F, Burrows JF, Mills IG, Evergren E., Free PMC Article | 02/5/2022 |
| Targeting CAMKK2 and SOC Channels as a Novel Therapeutic Approach for Sensitizing Acute Promyelocytic Leukemia Cells to All-Trans Retinoic Acid. | Targeting CAMKK2 and SOC Channels as a Novel Therapeutic Approach for Sensitizing Acute Promyelocytic Leukemia Cells to All-Trans Retinoic Acid.
Merhi F, Alvarez-Valadez K, Trepiana J, Lescoat C, Groppi A, Dupuy JW, Soubeyran P, Kroemer G, Vacher P, Djavaheri-Mergny M., Free PMC Article | 01/22/2022 |
| NCAPD2 inhibits autophagy by regulating Ca(2+)/CAMKK2/AMPK/mTORC1 pathway and PARP-1/SIRT1 axis to promote colorectal cancer. | NCAPD2 inhibits autophagy by regulating Ca(2+)/CAMKK2/AMPK/mTORC1 pathway and PARP-1/SIRT1 axis to promote colorectal cancer.
Jing Z, He X, Jia Z, Sa Y, Yang B, Liu P. | 01/8/2022 |
| Hyperactivation of MEK/ERK pathway by Ca(2+) /calmodulin-dependent protein kinase kinase 2 promotes cellular proliferation by activating cyclin-dependent kinases and minichromosome maintenance protein in gastric cancer cells. | Hyperactivation of MEK/ERK pathway by Ca(2+) /calmodulin-dependent protein kinase kinase 2 promotes cellular proliferation by activating cyclin-dependent kinases and minichromosome maintenance protein in gastric cancer cells.
Najar MA, Aravind A, Dagamajalu S, Sidransky D, Ashktorab H, Smoot DT, Gowda H, Prasad TSK, Modi PK, Chatterjee A. | 12/25/2021 |
| CARS senses cysteine deprivation to activate AMPK for cell survival. | CARS senses cysteine deprivation to activate AMPK for cell survival.
Yuan M, Yan R, Zhang Y, Qiu Y, Jiang Z, Liu H, Wang Y, Sun L, Zhang H, Gao P., Free PMC Article | 12/18/2021 |
| Immunohistochemical evidence of P2X7R, P2X4R and CaMKK2 in pyramidal neurons of frontal cortex does not align with Alzheimer's disease. | Immunohistochemical evidence of P2X7R, P2X4R and CaMKK2 in pyramidal neurons of frontal cortex does not align with Alzheimer's disease.
Gaff J, Jackaman C, Papadimitriou J, Waters S, McLean C, Price P. | 09/4/2021 |
| Association analysis between CAMKK2 rs1063843 and patients with schizophrenia in a Han Chinese population. | Association analysis between CAMKK2 rs1063843 and patients with schizophrenia in a Han Chinese population.
Qian L, Zhou D, Zhang F, Chen X, Yang B, Dong K, Wang Z, Zhang K. | 08/28/2021 |
| CAMKK2-CAMK4 signaling regulates transferrin trafficking, turnover, and iron homeostasis. | CAMKK2-CAMK4 signaling regulates transferrin trafficking, turnover, and iron homeostasis.
Sabbir MG., Free PMC Article | 08/14/2021 |
| Inhibition of CAMKK2 impairs autophagy and castration-resistant prostate cancer via suppression of AMPK-ULK1 signaling. | Inhibition of CAMKK2 impairs autophagy and castration-resistant prostate cancer via suppression of AMPK-ULK1 signaling.
Lin C, Blessing AM, Pulliam TL, Shi Y, Wilkenfeld SR, Han JJ, Murray MM, Pham AH, Duong K, Brun SN, Shaw RJ, Ittmann MM, Frigo DE., Free PMC Article | 07/31/2021 |
| Molecular Profiling Associated with Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2)-Mediated Carcinogenesis in Gastric Cancer. | Molecular Profiling Associated with Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2)-Mediated Carcinogenesis in Gastric Cancer.
Najar MA, Modi PK, Ramesh P, Sidransky D, Gowda H, Prasad TSK, Chatterjee A. | 07/31/2021 |
| Effects of Single-Nucleotide Polymorphisms in Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2): A Comprehensive Study. | Effects of Single-Nucleotide Polymorphisms in Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2): A Comprehensive Study.
Khalid Z, Almaghrabi O., Free PMC Article | 07/10/2021 |
| The role of CAMKK2 polymorphisms in HIV-associated sensory neuropathy in South Africans. | The role of CAMKK2 polymorphisms in HIV-associated sensory neuropathy in South Africans.
Gaff J, Pillay P, Cherry C, Laws SM, Price P, Kamerman P. | 06/26/2021 |
| MiR-1271 regulates glioblastoma cell proliferation and invasion by directly targeting the CAMKK2 gene. | MiR-1271 regulates glioblastoma cell proliferation and invasion by directly targeting the CAMKK2 gene.
Huang YK, Su YF, Lieu AS, Loh JK, Li CY, Wu CH, Kuo KL, Lin CL. | 05/1/2021 |
| CaMKK2 is inactivated by cAMP-PKA signaling and 14-3-3 adaptor proteins. | CaMKK2 is inactivated by cAMP-PKA signaling and 14-3-3 adaptor proteins.
Langendorf CG, O'Brien MT, Ngoei KRW, McAloon LM, Dhagat U, Hoque A, Ling NXY, Dite TA, Galic S, Loh K, Parker MW, Oakhill JS, Kemp BE, Scott JW., Free PMC Article | 03/13/2021 |
| Protein kinase A negatively regulates VEGF-induced AMPK activation by phosphorylating CaMKK2 at serine 495. | Protein kinase A negatively regulates VEGF-induced AMPK activation by phosphorylating CaMKK2 at serine 495.
Spengler K, Zibrova D, Woods A, Langendorf CG, Scott JW, Carling D, Heller R. | 02/27/2021 |
| Functional analysis of an R311C variant of Ca(2+) -calmodulin-dependent protein kinase kinase-2 (CaMKK2) found as a de novo mutation in a patient with bipolar disorder. | Functional analysis of an R311C variant of Ca(2+) -calmodulin-dependent protein kinase kinase-2 (CaMKK2) found as a de novo mutation in a patient with bipolar disorder.
Xy Ling N, Langendorf CG, Hoque A, Galic S, Loh K, Kemp BE, Gundlach AL, Oakhill JS, Scott JW. | 02/6/2021 |