| PLIN5 interacts with FATP4 at membrane contact sites to promote lipid droplet-to-mitochondria fatty acid transport. | PLIN5 interacts with FATP4 at membrane contact sites to promote lipid droplet-to-mitochondria fatty acid transport.
Miner GE, So CM, Edwards W, Ragusa JV, Wine JT, Wong Gutierrez D, Airola MV, Herring LE, Coleman RA, Klett EL, Cohen S., | 08/3/2023 |
| SLC27A4-mediated selective uptake of mono-unsaturated fatty acids promotes ferroptosis defense in hepatocellular carcinoma. | SLC27A4-mediated selective uptake of mono-unsaturated fatty acids promotes ferroptosis defense in hepatocellular carcinoma.
Li Z, Liao X, Hu Y, Li M, Tang M, Zhang S, Mo S, Li X, Chen S, Qian W, Feng R, Yu R, Xu Y, Yuan S, Xie C, Li J. | 05/31/2023 |
| The positive feedback between ACSL4 expression and O-GlcNAcylation contributes to the growth and survival of hepatocellular carcinoma. | The positive feedback between ACSL4 expression and O-GlcNAcylation contributes to the growth and survival of hepatocellular carcinoma.
Wang J, Wang Z, Yuan J, Wang J, Shen X., Free PMC Article | 02/27/2021 |
| Physical Activity During Pregnancy Is Associated with Increased Placental FATP4 Protein Expression. | Physical Activity During Pregnancy Is Associated with Increased Placental FATP4 Protein Expression.
Hutchinson KA, Vuong NH, Mohammad S, Everest C, Leung ML, Bhattacharjee J, Adamo KB. | 12/19/2020 |
| Impacts of deletion and ichthyosis prematurity syndrome-associated mutations in fatty acid transport protein 4 on the function of RPE65. | Impacts of deletion and ichthyosis prematurity syndrome-associated mutations in fatty acid transport protein 4 on the function of RPE65.
Li S, Green JF, Jin M., Free PMC Article | 10/10/2020 |
| High FATP4 expression was associated with poor prognosis in clear cell renal cell carcinoma. | High Membranous Expression of Fatty Acid Transport Protein 4 Is Associated with Tumorigenesis and Tumor Progression in Clear Cell Renal Cell Carcinoma.
Kim YS, Jung J, Jeong H, Lee JH, Oh HE, Lee ES, Choi JW., Free PMC Article | 08/31/2019 |
| high SLC27A4 is associated with tumor progression in breast cancer cells. | Solute Carrier Family 27 Member 4 (SLC27A4) Enhances Cell Growth, Migration, and Invasion in Breast Cancer Cells.
Yen MC, Chou SK, Kan JY, Kuo PL, Hou MF, Hsu YL., Free PMC Article | 02/9/2019 |
| Case Report: ichthyosis prematurity syndrome caused by novel homozygous mutation in SLC27A4. | Ichthyosis Prematurity Syndrome due to a Novel SLC27A4 Homozygous Mutation in an Italian Patient.
Diociaiuti A, Rosati E, Paglietti MG, Vacca P, Boldrini R, Pisaneschi E, Castiglia D, Novelli A, El Hachem M. | 01/19/2019 |
| SLC27A4 gene mutation is responsible in the diagnosis of ichthyosis prematurity syndrome in a premature infant. | Ichthyosis prematurity syndrome mimics keratitis-ichthyosis-deafness syndrome at birth: Use of electron microscopy and genetic testing.
Youssef MJ, Wolz MM, Harris MN, Richard G, Bridges AG, Wieland CN, Hand JL. | 07/1/2017 |
| expand the mutational repertory of FATP4 with three undescribed pathogenic mutations in two families | Novel mutations in FATP4 gene in two families with ichthyosis prematurity syndrome.
Bueno E, Cañueto J, García-Patos V, Vicente MA, Bodet-Castillo D, Hernández-Ruíz ME, González-Sarmiento R. | 05/6/2017 |
| The results have interesting implications that SLC27A4/ATG4B complex might be conducive to the occurrence of autophagy in human cancer cells, which is meaningful investigations toward the aim of developing autophagy-targeting drugs and have significant values in clinical application. | SLC27A4 regulate ATG4B activity and control reactions to chemotherapeutics-induced autophagy in human lung cancer cells.
Wu S, Su J, Qian H, Guo T. | 02/18/2017 |
| no association between placental expression and maternal body mass index | Protein expression of fatty acid transporter 2 is polarized to the trophoblast basal plasma membrane and increased in placentas from overweight/obese women.
Lager S, Ramirez VI, Gaccioli F, Jang B, Jansson T, Powell TL., Free PMC Article | 01/14/2017 |
| we resequenced the SLC27A3 and SLC27A4 genes using 267 autism spectrum disorders(ASD) patient and 1140 control samples and detected 47 and 30 variants for the SLC27A3 and SLC27A4, revealing that they are highly polymorphic with multiple rare variants. | Investigation of the fatty acid transporter-encoding genes SLC27A3 and SLC27A4 in autism.
Maekawa M, Iwayama Y, Ohnishi T, Toyoshima M, Shimamoto C, Hisano Y, Toyota T, Balan S, Matsuzaki H, Iwata Y, Takagai S, Yamada K, Ota M, Fukuchi S, Okada Y, Akamatsu W, Tsujii M, Kojima N, Owada Y, Okano H, Mori N, Yoshikawa T., Free PMC Article | 09/10/2016 |
| We describe two siblings with ichthyosis prematurity syndrome and report a recurrent homozygous mutation (c.1430T>A) that is predicted to lead to a p.Val477Asp substitution in fatty acid transport protein 4. | Ichthyosis prematurity syndrome: a case report and review of known mutations.
Kiely C, Devaney D, Fischer J, Lenane P, Irvine AD. | 05/16/2015 |
| the cell surface protein CD36/FAT directly facilitates fatty acid transport across the plasma membrane, whereas the intracellular acyl-CoA synthetases FATP4 and ACSL1 enhance fatty acid uptake indirectly by metabolic trapping | Protein mediated fatty acid uptake: synergy between CD36/FAT-facilitated transport and acyl-CoA synthetase-driven metabolism.
Schneider H, Staudacher S, Poppelreuther M, Stremmel W, Ehehalt R, Füllekrug J. | 05/10/2014 |
| the clinical implications of defects in these transporters and relevant animal models, including the FATP4 animal models and ichthyosis prematurity syndrome, a congenital ichthyosis caused by FATP4 deficiency. [review] | Fatty acid transporters in skin development, function and disease.
Lin MH, Khnykin D., Free PMC Article | 04/19/2014 |
| FATP4, ichthyin and TGM1 interact in lipid processing essential for maintaining the epidermal barrier function | Interactions between FATP4 and ichthyin in epidermal lipid processing may provide clues to the pathogenesis of autosomal recessive congenital ichthyosis.
Li H, Vahlquist A, Törmä H. | 09/28/2013 |
| FATP4 plays crucial roles in the development and maturation of both sebaceous and meibomian glands, as well as in the formation and composition of sebum | Requirement of fatty acid transport protein 4 for development, maturation, and function of sebaceous glands in a mouse model of ichthyosis prematurity syndrome.
Lin MH, Hsu FF, Miner JH., Free PMC Article | 04/20/2013 |
| FATP1 and FATP4 proteins perform different functional roles in handling long chain fatty acids in skeletal muscle | Enhanced fatty acid oxidation and FATP4 protein expression after endurance exercise training in human skeletal muscle.
Jeppesen J, Jordy AB, Sjøberg KA, Füllekrug J, Stahl A, Nybo L, Kiens B., Free PMC Article | 05/19/2012 |
| even though hypoxia regulates the expression of FATP2 and FATP4 in human trophoblasts, mouse Fatp2 and Fatp4 are not essential for intrauterine fetal growth. | The expression and function of fatty acid transport protein-2 and -4 in the murine placenta.
Mishima T, Miner JH, Morizane M, Stahl A, Sadovsky Y., Free PMC Article | 02/25/2012 |
| Mutation in FATP4 in a patient with self-healing congenital verruciform hyperkeratosis.( | A novel mutation in the fatty acid transport protein 4 gene in a patient initially described as affected by self-healing congenital verruciform hyperkeratosis.
Morice-Picard F, Léauté-Labrèze C, Décor A, Boralevi F, Lacombe D, Taieb A, Fischer J. | 11/27/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (2) articlesGenetic variability of the fatty acid synthase pathway is not associated with prostate cancer risk in the European Prospective Investigation on Cancer (EPIC).
Campa D, Hüsing A, Chang-Claude J, Dostal L, Boeing H, Kröger J, Tjønneland A, Roswall N, Overvad K, Dahm CC, Rodríguez L, Sala N, Pérez MJ, Larrañaga N, Chirlaque MD, Ardanaz E, Khaw KT, Wareham N, Allen NE, Travis RC, Trichopoulou A, Naska A, Bamia C, Palli D, Sieri S, Tumino R, Sacerdote C, van Kranen HJ, Bas Bueno-de-Mesquita H, Stattin P, Johansson M, Chajes V, Rinaldi S, Romieu I, Siddiq A, Norat T, Riboli E, Kaaks R, Canzian F. L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.
Yokoyama K, Urashima M, Ohkido I, Kono T, Yoshida T, Muramatsu M, Niu T, Hosoya T. | 06/30/2010 |
| Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) | Identification of type 2 diabetes-associated combination of SNPs using support vector machine.
Ban HJ, Heo JY, Oh KS, Park KJ., Free PMC Article | 06/30/2010 |
| Mutations in FATP4 gene cause the ichthyosis prematurity syndrome. | Mutations in the fatty acid transport protein 4 gene cause the ichthyosis prematurity syndrome.
Klar J, Schweiger M, Zimmerman R, Zechner R, Li H, Törmä H, Vahlquist A, Bouadjar B, Dahl N, Fischer J., Free PMC Article | 01/21/2010 |
| Data suggest that endogenous FATP4 does not function to translocate fatty acids across the plasma membrane, but functions more as a very long-chain acyl-CoA synthetase. | The fatty acid transport protein (FATP) family: very long chain acyl-CoA synthetases or solute carriers?
Jia Z, Pei Z, Maiguel D, Toomer CJ, Watkins PA. | 01/21/2010 |