Tubular deficiency of ABCA1 augments cholesterol- and Na[+]-dependent effects on systemic blood pressure in male mice. | Tubular deficiency of ABCA1 augments cholesterol- and Na(+)-dependent effects on systemic blood pressure in male mice. Carneiro de Oliveira K, Wei Y, Repetti RL, Meth J, Majumder N, Sapkota A, Gusella GL, Rohatgi R. | 02/5/2024 |
Paradoxical effect of Abeta on protein levels of ABCA1 in astrocytes, microglia, and neurons isolated from C57BL/6 mice: an in vitro and in silico study to elucidate the effect of Abeta on ABCA1 in the brain cells. | Paradoxical effect of Aβ on protein levels of ABCA1 in astrocytes, microglia, and neurons isolated from C57BL/6 mice: an in vitro and in silico study to elucidate the effect of Aβ on ABCA1 in the brain cells. Zarezade V, Nazeri Z, Azizidoost S, Cheraghzadeh M, Babaahmadi-Rezaei H, Kheirollah A. | 01/5/2024 |
Macrophage Gpx4 deficiency aggravates foam cell formation by regulating the expression of scavenger receptors, ABCA1, and ABCG1. | Macrophage Gpx4 deficiency aggravates foam cell formation by regulating the expression of scavenger receptors, ABCA1, and ABCG1. Zhou J, Wu S, Chen X, Hou L, Zhong Q, Luo W, Dai C, Dai X. | 08/9/2023 |
Cholesterol homeostasis regulated by ABCA1 is critical for retinal ganglion cell survival. | Cholesterol homeostasis regulated by ABCA1 is critical for retinal ganglion cell survival. Yang J, Chen Y, Zou T, Xue B, Yang F, Wang X, Huo Y, Yan B, Xu Y, He S, Yin Y, Wang J, Zhu X, Zhang L, Zhou Y, Tai Z, Shuai P, Yu M, Luo Q, Cheng Y, Gong B, Zhu X, Zhang J, Sun X, Lin Y, Zhang H, Yang Z. | 02/24/2023 |
ABCA1-Mediated EMT Promotes Papillary Thyroid Cancer Malignancy through the ERK/Fra-1/ZEB1 Pathway. | ABCA1-Mediated EMT Promotes Papillary Thyroid Cancer Malignancy through the ERK/Fra-1/ZEB1 Pathway. Park JH, Myung JK, Lee SJ, Kim H, Kim S, Lee SB, Jang H, Jang WI, Park S, Yang H, Shim S, Kim MJ., Free PMC Article | 02/11/2023 |
ABCA1 deficiency-mediated glomerular cholesterol accumulation exacerbates glomerular endothelial injury and dysfunction in diabetic kidney disease. | ABCA1 deficiency-mediated glomerular cholesterol accumulation exacerbates glomerular endothelial injury and dysfunction in diabetic kidney disease. Zhang J, Wu Y, Zhang J, Zhang R, Wang Y, Liu F. | 01/11/2023 |
MiR-145 is upregulated in the retarded preimplantation embryos and modulates cholesterol levels in mice preimplantation embryos through targeting Abca1. | MiR-145 is upregulated in the retarded preimplantation embryos and modulates cholesterol levels in mice preimplantation embryos through targeting Abca1. Jian O, MengXia N, Shiyu X, QingXia M, QinYan Z, Jie D, Wei W, Jiaojiao W, Hong L, Yining H., Free PMC Article | 12/24/2022 |
Specific Loss of ABCA1 (ATP-Binding Cassette Transporter A1) Suppresses TCR (T-Cell Receptor) Signaling and Provides Protection Against Atherosclerosis. | Specific Loss of ABCA1 (ATP-Binding Cassette Transporter A1) Suppresses TCR (T-Cell Receptor) Signaling and Provides Protection Against Atherosclerosis. Zhao Y, Zhang L, Liu L, Zhou X, Ding F, Yang Y, Du S, Wang H, Van Eck M, Wang J. | 11/26/2022 |
Apolipoprotein A-I Inhibits Transendothelial Transport of Apolipoprotein B-Carrying Lipoproteins and Enhances Its Associated High-Density Lipoprotein Formation. | Apolipoprotein A-I Inhibits Transendothelial Transport of Apolipoprotein B-Carrying Lipoproteins and Enhances Its Associated High-Density Lipoprotein Formation. Guo Z, Zhang N, Yang H., Free PMC Article | 10/29/2022 |
CTRP15 promotes macrophage cholesterol efflux and attenuates atherosclerosis by increasing the expression of ABCA1. | CTRP15 promotes macrophage cholesterol efflux and attenuates atherosclerosis by increasing the expression of ABCA1. Tan WH, Peng ZL, You T, Sun ZL. | 08/27/2022 |
Proteus mirabilis Vesicles Induce Mitochondrial Apoptosis by Regulating miR96-5p/Abca1 to Inhibit Osteoclastogenesis and Bone Loss. | Proteus mirabilis Vesicles Induce Mitochondrial Apoptosis by Regulating miR96-5p/Abca1 to Inhibit Osteoclastogenesis and Bone Loss. Wang T, Mo L, Ou J, Fang Q, Wu H, Wu Y, Nandakumar KS., Free PMC Article | 05/14/2022 |
Hormone-sensitive lipase deficiency affects the expression of SR-BI, LDLr, and ABCA1 receptors/transporters involved in cellular cholesterol uptake and efflux and disturbs fertility in mouse testis. | Hormone-sensitive lipase deficiency affects the expression of SR-BI, LDLr, and ABCA1 receptors/transporters involved in cellular cholesterol uptake and efflux and disturbs fertility in mouse testis. Casado ME, Huerta L, Marcos-Díaz A, Ortiz AI, Kraemer FB, Lasunción MA, Busto R, Martín-Hidalgo A. | 01/8/2022 |
Amyloid beta increases ABCA1 and HMGCR protein expression, and cholesterol synthesis and accumulation in mice neurons and astrocytes. | Amyloid beta increases ABCA1 and HMGCR protein expression, and cholesterol synthesis and accumulation in mice neurons and astrocytes. Azizidoost S, Babaahmadi-Rezaei H, Nazeri Z, Cheraghzadeh M, Kheirollah A. | 01/1/2022 |
Thrombin-Par1 signaling axis disrupts COP9 signalosome subunit 3-mediated ABCA1 stabilization in inducing foam cell formation and atherogenesis. | Thrombin-Par1 signaling axis disrupts COP9 signalosome subunit 3-mediated ABCA1 stabilization in inducing foam cell formation and atherogenesis. Boro M, Govatati S, Kumar R, Singh NK, Pichavaram P, Traylor JG Jr, Orr AW, Rao GN., Free PMC Article | 12/18/2021 |
High density lipoproteins mediate in vivo protection against staphylococcal phenol-soluble modulins. | High density lipoproteins mediate in vivo protection against staphylococcal phenol-soluble modulins. Hommes JW, Kratofil RM, Wahlen S, de Haas CJC, Hildebrand RB, Hovingh GK, Otto M, van Eck M, Hoekstra M, Korporaal SJA, Surewaard BGJ., Free PMC Article | 11/6/2021 |
Protective role of ABCA1 in ischemic preconditioning is mediated by downregulation of miR-33-5p and miR-135-5p. | Protective role of ABCA1 in ischemic preconditioning is mediated by downregulation of miR-33-5p and miR-135-5p. Sung HY, Choi EN, Han J, Chae YJ, Im SW, Kim HS, Park EM, Ahn JH., Free PMC Article | 10/30/2021 |
Role of Tim4 in the regulation of ABCA1(+) adipose tissue macrophages and post-prandial cholesterol levels. | Role of Tim4 in the regulation of ABCA1(+) adipose tissue macrophages and post-prandial cholesterol levels. Magalhaes MS, Smith P, Portman JR, Jackson-Jones LH, Bain CC, Ramachandran P, Michailidou Z, Stimson RH, Dweck MR, Denby L, Henderson NC, Jenkins SJ, Bénézech C., Free PMC Article | 08/7/2021 |
Apolipoprotein A-I in mouse cerebrospinal fluid derives from the liver and intestine via plasma high-density lipoproteins assembled by ABCA1 and LCAT. | Apolipoprotein A-I in mouse cerebrospinal fluid derives from the liver and intestine via plasma high-density lipoproteins assembled by ABCA1 and LCAT. Tsujita M, Vaisman B, Chengyu L, Vickers KC, Okuhira KI, Braesch-Andersen S, Remaley AT., Free PMC Article | 07/24/2021 |
Myocardin suppression increases lipid retention and atherosclerosis via downregulation of ABCA1 in vascular smooth muscle cells. | Myocardin suppression increases lipid retention and atherosclerosis via downregulation of ABCA1 in vascular smooth muscle cells. Xia XD, Yu XH, Chen LY, Xie SL, Feng YG, Yang RZ, Zhao ZW, Li H, Wang G, Tang CK. | 07/3/2021 |
Malaria in pregnancy regulates P-glycoprotein (P-gp/Abcb1a) and ABCA1 efflux transporters in the Mouse Visceral Yolk Sac. | Malaria in pregnancy regulates P-glycoprotein (P-gp/Abcb1a) and ABCA1 efflux transporters in the Mouse Visceral Yolk Sac. Martinelli LM, Fontes KN, Reginatto MW, Andrade CBV, Monteiro VRS, Gomes HR, Silva-Filho JL, Pinheiro AAS, Vago AR, Almeida FRCL, Bloise FF, Matthews SG, Ortiga-Carvalho TM, Bloise E., Free PMC Article | 05/15/2021 |
ABCA1 Exerts Tumor-Suppressor Function in Myeloproliferative Neoplasms. | ABCA1 Exerts Tumor-Suppressor Function in Myeloproliferative Neoplasms. Viaud M, Abdel-Wahab O, Gall J, Ivanov S, Guinamard R, Sore S, Merlin J, Ayrault M, Guilbaud E, Jacquel A, Auberger P, Wang N, Levine RL, Tall AR, Yvan-Charvet L., Free PMC Article | 03/27/2021 |
Silencing SGK1 alleviates osteoarthritis through epigenetic regulation of CREB1 and ABCA1 expression. | Silencing SGK1 alleviates osteoarthritis through epigenetic regulation of CREB1 and ABCA1 expression. Wang Z, Ni S, Zhang H, Fan Y, Xia L, Li N. | 03/6/2021 |
ABCA1/ApoE/HDL Signaling Pathway Facilitates Myelination and Oligodendrogenesis after Stroke. | ABCA1/ApoE/HDL Signaling Pathway Facilitates Myelination and Oligodendrogenesis after Stroke. Li L, Li R, Zacharek A, Wang F, Landschoot-Ward J, Chopp M, Chen J, Cui X., Free PMC Article | 02/13/2021 |
CXCL12 promotes atherosclerosis by downregulating ABCA1 expression via the CXCR4/GSK3beta/beta-catenin(T120)/TCF21 pathway | CXCL12 promotes atherosclerosis by downregulating ABCA1 expression via the CXCR4/GSK3β/β-catenin(T120)/TCF21 pathway. Gao JH, He LH, Yu XH, Zhao ZW, Wang G, Zou J, Wen FJ, Zhou L, Wan XJ, Zhang DW, Tang CK., Free PMC Article | 07/11/2020 |
ABCA1-mediated cholesterol efflux by sphingosine-1-phosphate signaling in macrophages | Regulation of ABCA1-mediated cholesterol efflux by sphingosine-1-phosphate signaling in macrophages. Vaidya M, Jentsch JA, Peters S, Keul P, Weske S, Gräler MH, Mladenov E, Iliakis G, Heusch G, Levkau B., Free PMC Article | 06/20/2020 |