A Complex Interplay of DJ-1, LRRK2, and Nrf2 in the Regulation of Mitochondrial Function in Cypermethrin-Induced Parkinsonism. | A Complex Interplay of DJ-1, LRRK2, and Nrf2 in the Regulation of Mitochondrial Function in Cypermethrin-Induced Parkinsonism. Sarkar A, Singh MP. | 02/15/2024 |
DJ-1: A Potential Biomarker Related to Prognosis, Chemoresistance, and Expression of Microenvironmental Chemokine in HR-Positive Breast Cancer. | DJ-1: A Potential Biomarker Related to Prognosis, Chemoresistance, and Expression of Microenvironmental Chemokine in HR-Positive Breast Cancer. Xie Y, Li Y, Yang M., Free PMC Article | 01/3/2024 |
TrkB inhibition of DJ-1 degradation promotes the growth and maintenance of cancer stem cell characteristics in hepatocellular carcinoma. | TrkB inhibition of DJ-1 degradation promotes the growth and maintenance of cancer stem cell characteristics in hepatocellular carcinoma. Kim MS, Lee WS, Jin W., Free PMC Article | 09/29/2023 |
WTAP-mediated m6A modification on circCMTM3 inhibits hepatocellular carcinoma ferroptosis by recruiting IGF2BP1 to increase PARK7 stability. | WTAP-mediated m6A modification on circCMTM3 inhibits hepatocellular carcinoma ferroptosis by recruiting IGF2BP1 to increase PARK7 stability. Chen S, Xia H, Sheng L. | 06/30/2023 |
Disease-Modifying Effects of Vincamine Supplementation in Drosophila and Human Cell Models of Parkinson's Disease Based on DJ-1 Deficiency. | Disease-Modifying Effects of Vincamine Supplementation in Drosophila and Human Cell Models of Parkinson's Disease Based on DJ-1 Deficiency. Sanz FJ, Solana-Manrique C, Paricio N., Free PMC Article | 06/28/2023 |
PARK7/DJ-1 in microglia: implications in Parkinson's disease and relevance as a therapeutic target. | PARK7/DJ-1 in microglia: implications in Parkinson's disease and relevance as a therapeutic target. Lind-Holm Mogensen F, Scafidi A, Poli A, Michelucci A., Free PMC Article | 05/19/2023 |
Kinetic evidence in favor of glyoxalase III and against deglycase activity of DJ-1. | Kinetic evidence in favor of glyoxalase III and against deglycase activity of DJ-1. Choi J, Tak S, Jung HM, Cha S, Hwang E, Lee D, Lee JH, Ryu KS, Park C., Free PMC Article | 05/8/2023 |
Parkinsonism-Associated Protein DJ-1 Is an Antagonist, Not an Eraser, for Protein Glycation. | Parkinsonism-Associated Protein DJ-1 Is an Antagonist, Not an Eraser, for Protein Glycation. Gao Q, Jacob-Dolan JW, Scheck RA., Free PMC Article | 03/26/2023 |
Parkinson's disease-associated 18 bp promoter variant of DJ-1 alters REST binding and regulates its expression. | Parkinson's disease-associated 18 bp promoter variant of DJ-1 alters REST binding and regulates its expression. Pal P, Roy S, Chowdhury A, Chatterjee R, Ray K, Ray J. | 03/1/2023 |
Searching for Biomarkers in the Blood of Patients at Risk of Developing Parkinson's Disease at the Prodromal Stage. | Searching for Biomarkers in the Blood of Patients at Risk of Developing Parkinson's Disease at the Prodromal Stage. Katunina EA, Blokhin V, Nodel MR, Pavlova EN, Kalinkin AL, Kucheryanu VG, Alekperova L, Selikhova MV, Martynov MY, Ugrumov MV., Free PMC Article | 02/16/2023 |
PARK7/DJ-1 inhibition decreases invasion and proliferation of uveal melanoma cells. | PARK7/DJ-1 inhibition decreases invasion and proliferation of uveal melanoma cells. Lago-Baameiro N, Santiago-Varela M, Camino T, Silva-Rodríguez P, Bande M, Blanco-Teijeiro MJ, Pardo M, Piñeiro A. | 02/11/2023 |
DJ-1 is an essential downstream mediator in PINK1/parkin-dependent mitophagy. | DJ-1 is an essential downstream mediator in PINK1/parkin-dependent mitophagy. Imberechts D, Kinnart I, Wauters F, Terbeek J, Manders L, Wierda K, Eggermont K, Madeiro RF, Sue C, Verfaillie C, Vandenberghe W., Free PMC Article | 01/21/2023 |
DJ-1 activates the AMPK/mTOR pathway by binding RACK1 to induce autophagy and protect the myocardium from ischemia/hypoxia injury. | DJ-1 activates the AMPK/mTOR pathway by binding RACK1 to induce autophagy and protect the myocardium from ischemia/hypoxia injury. Zhao XY, Ren JM, Liu HR, Zhou TT, Wang XY, Liu S, Chen HP. | 12/10/2022 |
Gene-based burden analysis of damaging private variants in PRKN, PARK7 and PINK1 in Parkinson's disease cohorts of European descent. | Gene-based burden analysis of damaging private variants in PRKN, PARK7 and PINK1 in Parkinson's disease cohorts of European descent. Hu J, Waters CH, Spiegelman D, Fon EA, Yu E, Asayesh F, Krohn L, Saini P, Alcalay RN, Hassin-Baer S, Gan-Or Z, Krainc D, Zhang B, Bustos BI, Lubbe SJ, International Parkinson's Disease Genomics Consortium (IPDGC). | 11/5/2022 |
DJ-1 controls T cell differentiation and osteoclastogenesis in rheumatoid arthritis. | DJ-1 controls T cell differentiation and osteoclastogenesis in rheumatoid arthritis. Min HK, Kim SH, Lee JY, Lee SH, Kim HR., Free PMC Article | 08/6/2022 |
Identifying chronic alcoholism drug disulfiram as a potent DJ-1 inhibitor for cancer therapeutics. | Identifying chronic alcoholism drug disulfiram as a potent DJ-1 inhibitor for cancer therapeutics. Wu Q, Zhang M, Wen Y, He P, He Q, Yang B, Jiang L, Yuan M, Cao J. | 07/2/2022 |
DJ-1 activates the Atg5-Atg12-Atg16L1 complex via Sirt1 to influence microglial polarization and alleviate cerebral ischemia/reperfusion-induced inflammatory injury. | DJ-1 activates the Atg5-Atg12-Atg16L1 complex via Sirt1 to influence microglial polarization and alleviate cerebral ischemia/reperfusion-induced inflammatory injury. Zhao N, Li Y, Wang C, Xue Y, Peng L, Wang T, Zhao Y, Xu G, Yu S. | 06/18/2022 |
Moving beyond the Tip of the Iceberg: DJ-1 Implications in Cancer Metabolism. | Moving beyond the Tip of the Iceberg: DJ-1 Implications in Cancer Metabolism. Olivo E, La Chimia M, Ceramella J, Catalano A, Chiaradonna F, Sinicropi MS, Cuda G, Iacopetta D, Scumaci D., Free PMC Article | 05/28/2022 |
Early-Onset Parkinson's Disease and Brain Iron Accumulation Caused by a Novel Homozygous DJ-1 Mutation. | Early-Onset Parkinson's Disease and Brain Iron Accumulation Caused by a Novel Homozygous DJ-1 Mutation. Lin RR, Tao QQ, Wu ZY. | 04/23/2022 |
PARKIN, PINK1, and DJ1 analysis in early-onset Parkinson's disease in Ireland. | PARKIN, PINK1, and DJ1 analysis in early-onset Parkinson's disease in Ireland. Olszewska DA, McCarthy A, Soto-Beasley AI, Walton RL, Ross OA, Lynch T., Free PMC Article | 04/16/2022 |
Early-Onset Parkinson's Disease: A Novel Deletion Comprising the DJ-1 and TNFRSF9 Genes. | Early-Onset Parkinson's Disease: A Novel Deletion Comprising the DJ-1 and TNFRSF9 Genes. Güler S, Gül T, Güler Ş, Haerle MC, Başak AN. | 04/9/2022 |
A longitudinal study of alterations of circulating DJ-1 and miR203a-3p in association to olanzapine medication in a sample of first episode patients with schizophrenia. | A longitudinal study of alterations of circulating DJ-1 and miR203a-3p in association to olanzapine medication in a sample of first episode patients with schizophrenia. Tsoporis JN, Ektesabi AM, Gupta S, Izhar S, Salpeas V, Rizos IK, Kympouropoulos SP, Dos Santos CC, Parker TG, Rizos E. | 04/2/2022 |
DJ-1 upregulates the Nrf2/GPX4 signal pathway to inhibit trophoblast ferroptosis in the pathogenesis of preeclampsia. | DJ-1 upregulates the Nrf2/GPX4 signal pathway to inhibit trophoblast ferroptosis in the pathogenesis of preeclampsia. Liao T, Xu X, Ye X, Yan J., Free PMC Article | 03/19/2022 |
DJ-1 activates the noncanonical NF-kappaB pathway via interaction with Cezanne to inhibit the apoptosis and promote the proliferation of Ishikawa cells. | DJ-1 activates the noncanonical NF-κB pathway via interaction with Cezanne to inhibit the apoptosis and promote the proliferation of Ishikawa cells. Zhu QZ, Liu HY, Zhao XY, Qiu LJ, Zhou TT, Wang XY, Chen HP, Xiao ZQ. | 01/29/2022 |
Frequency of mutations in PRKN, PINK1, and DJ1 in Patients With Early-Onset Parkinson Disease from neighboring countries in Central Europe. | Frequency of mutations in PRKN, PINK1, and DJ1 in Patients With Early-Onset Parkinson Disease from neighboring countries in Central Europe. Milanowski ŁM, Lindemann JA, Hoffman-Zacharska D, Soto-Beasley AI, Barcikowska M, Boczarska-Jedynak M, Deutschlander A, Kłodowska G, Dulski J, Fedoryshyn L, Friedman A, Jamrozik Z, Janik P, Karpinsky K, Koziorowski D, Krygowska-Wajs A, Jasińska-Myga B, Opala G, Potulska-Chromik A, Pulyk A, Rektorova I, Sanotsky Y, Siuda J, Sławek J, Śmiłowska K, Szczechowski L, Rudzińska-Bar M, Walton RL, Ross OA, Wszolek ZK., Free PMC Article | 01/29/2022 |